Abstract: A laser device is disclosed that provides at least an ultraviolet laser beam and preferably both an ultraviolet laser beam and a visible laser beam. The laser device includes a semiconductor laser device (e.g. a laser diode) to generate visible laser light which is coupled into a frequency doubling crystal taking the form of a single crystal thin film frequency-doubling waveguide structure. The single crystal thin film frequency-doubling waveguide converts a portion of the visible light emitted by the laser diode into ultraviolet light. Both visible and ultraviolet laser light is emitted from the waveguide. As an example, the single crystal thin film frequency-doubling frequency doubling waveguide includes a frequency doubling crystal region composed of ?-BaB2O4 (?-BBO), a cladding region composed of materials that are transparent or nearly transparent at the wavelength of the ultraviolet laser light beam and a supporting substrate composed of any material.

Abstract: A system and method for processing a plurality of data storage and retrieval management or manifest files in a virtual data storage system. A plurality of individual management/manifest files, which are each used to track data management information stored on a data storage device, are merged into a single management or manifest file that can then be used to subsequently manage the input or import of data such as logical volumes from one or more physical media. This single management/manifest file could be used, for example, in a media import operation for importing a media cartridge or device into a media library such as a data storage library.

Abstract: A method of assessing the viability of a cell comprises incubating the cell in a culture medium. The culture medium includes a plurality of amino acids and the change in concentration in the medium of at least one amino acid is determined.

Abstract: A system for easily transferring an intraocular lens (IOL) from a lens case to an inserter, and then into a patient's eye. The lens case has a transfer mechanism therein which retains the IOL until engagement with the inserter. The transfer mechanism may include jaws having a closed configuration for retaining the IOL and an open configuration for releasing the IOL. Engagement of the inserter with the lens case automatically opens the jaws and transfers the IOL to the inserter. The IOL is transferred into a load chamber of a nosepiece rotatably coupled to a handpiece. After transfer of the IOL, the nosepiece is rotated from a load position to a delivery position. The IOL may have an optic and a haptic coupled to the optic, and the lens case may be capable of configuring the haptic as desired to facilitate its transfer into an inserter and/or into the eye. For instance, the lens case may fold one or both of the haptics over the optic.

Abstract: A lens case for storing an intraocular lens contains a housing for storing an intraocular lens and a support member configured to support the intraocular lens. The support member includes a plurality of jaws, the jaws having a closed configuration for holding the intraocular lens and an open configuration for releasing the intraocular lens. The lens case further comprises a passage formed when the jaws are in the open configuration, the passage including an opening in the lens case for transfer of the intraocular lens into an intraocular lens inserter. The lens case may further comprise an intraocular lens that is disposed between the jaws, the intraocular lens comprising an optic and a haptic coupled to the optic. The lens case may be configured to maintain the haptic in either a first position in which a distal portion of the haptic is disposed farther from the optic or a second position in which the distal portion of the haptic is disposed closer to optic.

Abstract: A lens and cartridge packaging system and method of use which simplify the removal and transfer of an IOL to an IOL insertion device is disclosed. The packaging system enables a user to easily load an IOL into a cartridge without the use of forceps. In addition, the packaging system also allows a user to fold and insert the IOL into a cartridge without damaging the IOL and/or compromising IOL sterility. In addition, the related methods of use minimize and/or eliminate damage to the IOL during unpackaging, folding, transfer and loading procedures.

Abstract: Apparatus for delivering brachytherapy to a target tissue region includes an elongate body including a proximal end, a distal end sized for introduction into a tissue tract and carrying a plurality of elongate members including pathways for receiving a source of radiation. The elongate members are movable between collapsed and expanded configurations. During use, a tract is created through tissue, and the elongate body carrying the elongate members is advanced through the tract into a target location with the elongate members in the collapsed configuration. The elongate members are directed to the expanded configuration at the target location, and radiation is delivered to treat tissue at the target location, e.g., by introducing one or more radiation sources along the pathways.

Abstract: A lens and cartridge packaging system and method of use which simplify the removal and transfer of an IOL to an IOL insertion device is disclosed. The packaging system enables a user to easily load an IOL into a cartridge without the use of forceps. In addition, the packaging system also allows a user to fold and insert the IOL into a cartridge without damaging the IOL and/or compromising IOL sterility. In addition, the related methods of use minimize and/or eliminate damage to the IOL during unpackaging, folding, transfer and loading procedures.

Abstract: A cartridge for delivering an intraocular lens into the eye of a subject that comprises a body disposed along a longitudinal axis having a distal end and a proximal end, and a tapered lumen disposed along the longitudinal axis having an aperture at the distal end of the body. The aperture and at least a portion of the tapered lumen each consist of an upper portion and a lower portion. The upper portions of the aperture and lumen each have a first width and a cross-section that is generally arcuate. The lower portions of the aperture and lumen each have a cross-section that is generally horizontally disposed and have a second width that is greater than the first width of the aperture and lumen. The cartridge may be loaded with an intraocular lens using a packaging system. The intraocular lens may be placed into the eye of a subject using a corresponding inserter having a pushrod with a saddle disposed at the tip thereof. The intraocular lens is preferably draped over the saddle during insertion.

Abstract: An insertion system is provided for delivering an intraocular lens into the eye of a subject. The insertion system comprises an inserter for delivering the intraocular lens and a lens case for holding the intraocular lens prior to delivery. The inserter comprises handpiece having a longitudinal axis, a proximal end, and a distal end. The inserter further comprises a nosepiece disposed at the distal end of the inserter, the nosepiece having a rotational axis that is substantially perpendicular to the longitudinal axis and a load chamber with a transfer interface for receiving the intraocular lens. The lens case has a transfer port for transferring the intraocular lens from the lens case into the load chamber. Once the intraocular lens is transferred into the load chamber, the nosepiece is adapted to rotate approximately 180 degrees about the rotational axis between a first position for loading the intraocular lens and a second position for delivering the intraocular lens into the eye.

Abstract: The present invention describes a means for fixing skin care ingredients on the surface of non-woven webs and cellulosic mats. The active ingredients can be released (deposited) onto the skin by normal triggering mechanisms, which include the action of water or urine or by friction or rubbing. The fixative systems described herein provide the ability to control high load levels while not interfering with the wettabliity of the fabric or paper. Additionally, incompatible/reactive ingredients can be treated onto the same web and are kept as separate particles fixed to the surface until released.

Abstract: An air particle sample cassette enables concurrent or sequential collection of air particle samples. The dual air particle sample cassette has top and bottom covers that fit together to provide an airtight seal between them. The airtight seal may be provided by adhesive or otherwise. However, a close fit between the two also aids in obtaining an airtight seal. The top cover has tapering inlets circumscribed by channels. The inlets taper to create increased air speed at the exit slit of the inlets. The inlets have rounded tops for greater collection of air and the circumscribing channels provide means by which plastic caps or otherwise may be used to protect the inlets from collecting air until desired. The sample plate or collecting slide is fitted to the bottom of the top cover and obstructs the direct flow of air to the exit port. The collecting slide is protected from contact with other cassette elements by spacers or sidewalls which generally leave the corners of the bottom cover open.

Abstract: An apparatus for controllably delivering an IOL into the eye of a patient is disclosed. The device is configured for convenient and reliable positioning of a plunger rod assembly at different stages of the IOL injection procedure, such that various aspects of the insertion procedure can be performed precisely and reliably by a user of the device. In addition, the present invention assists the user during the procedure by accurately and consistently positioning the plunger rod assembly prior to ejection of the folded or rolled IOL from the insertion device.

Abstract: An implantable marking device is provided which is designed to percutaneously deliver permanent markers to desired tissue locations within a patient's body, even if the desired locations are laterally disposed relative to the distal end of the delivery device, as is the case for conduit or cavity walls. This provides several advantages to the physician in diagnosis and management of tissue abnormalities, such as a means of localization of a tissue abnormality for follow-up surgical treatment, and a means of tissue abnormality site identification for purposes of ongoing diagnostic follow-up. In one preferred construction, a radiographic clip is configured in the form of a surgical staple. A disposable tissue marker applier, which comprises a flexible tube, pull wire, and squeeze handle, is employed to advance and deploy the clip to a desired tissue location. Either a flexible or a rigid introducer is also provided for providing access to the site to be marked.

Abstract: This invention provides an inventive tissue sampling probe which offers many advantages over probes available in the prior art. Unexpectedly superior results are obtained in connection with the retrieval of intact tissue specimens, because of a unique combination of cutting features, including, for example, the employment of an electrosurgical cutting element and a vacuum assist in one preferred embodiment. A particularly important feature of the invention is the ability to manipulate the electrosurgical cutting element to cleanly sever the distal end of the tissue specimen. In certain embodiments, this is accomplished without any cutting impact on surrounding tissue. The versatility of the invention permits its use in many applications, including, for example, breast biopsies, laparoscopic surgery, and lymphadenectomy procedures.

Abstract: An irrigation/aspiration apparatus is provided for use with surgical instrumentation requiring irrigation and aspiration of fluids and a peristaltic pump. The apparatus includes a housing and a manifold for connecting a transfer tube with aspiration and irrigation lines from the surgical instrumentation and with waste and supply lines. An opening the housing enables access to the transfer tube in order to control fluid flow therein. A diaphragm mounted to the housing and in fluid communication with the aspiration tube enables both pressure measurement and pressure control in the tubing when the housing is inserted into a drawer in the console and in operative engagement with a peristaltic pump head disposed therein.

Abstract: Method and apparatus for producing a vaporized fuel stream from a liquid fuel in which an inert gas is injected into a pressurized storage container containing the liquid fuel to provide a vaporized fuel stream having a substantially constant pressure, flow rate and composition.

Abstract: An irrigation/aspiration apparatus is provided for use with surgical instrumentation requiring irrigation and aspiration of fluids and a peristaltic pump. The apparatus includes a housing and a manifold for connecting a transfer tube with aspiration and irrigation lines from the surgical instrumentation and with waste and supply lines. An opening the housing enables access to the transfer tube in order to control fluid flow therein. A diaphragm mounted to the housing and in fluid communication with the aspiration tube enables both pressure measurement and pressure control in the tubing when the housing is inserted into a drawer in the console and in operative engagement with a peristaltic pump head disposed therein.

Abstract: A method is proposed for better determining the azimuth and inclination of a borehole in which a priori information regarding the magnitude of the earth's gravitational field strength, its magnetic field strength and direction are utilized to constrain the measured components of the earth's gravitational and magnetic field vectors. The constrained fit method adjusts the accelerometer and the magnetometer tri-axis measurements to optimize agreement between the measured data and the a priori magnetic and gravity field strengths and the magnetic dip angle. The adjustment that is selected is that which produces the least increase in the statistical measure .chi..sup.2.