Abstract: The invention describes novel spiropiperidines of Formula (1A), (1B), and (1C) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use in animals as an antiparasitic. The variables A, R1, R2, R3, R4, v, m, 5, and n are as described herein.

Abstract: The device utilizes a thruster cylinder driven by a enlarged knob and terminating in a thruster plate to clamp to a support. Provision is made to attach a device to the clamp through a rotating index wheel which can lock the device by receiving a tang from a trigger lever at a selected increment of rotation. A second embodiment has two index wheels so that the attached device can be displaced in one of four directions to avoid conflict with other devices on the same support. The second axis is normally used to return a displaced device to an upright orientation.

Abstract: Effective treatments of pain and/or inflammation for extended periods of time are provided. Through the administration of an effective amount of sulindac or a pharmaceutically acceptable salt thereof at or near a target site, one can relieve pain and/or inflammation caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days, at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

Abstract: The stand is attached to a wheeled frame by a cylindrical post received in a frame receiver attached to the frame and a rectangular beam is received in a tapered slot in the receiver and extends horizontally from the cylindrical post. The beam terminates at the end opposite the frame receiver in a vertical post.

Abstract: Effective treatments of pain and inflammation are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce, prevent or treat inflammation and pain and autoimmune disorders. In various embodiments, fluocinolone formulations may be provided within biodegradable polymers to reduce, prevent or treat sciatic pain and/or inflammation. In various embodiments, prevent transplant rejection for at least twenty-five days. In some embodiments, the pain relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

Abstract: Effective treatments of pain and inflammation are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce, prevent or treat inflammation and pain and autoimmune disorders. In various embodiments, fluocinolone formulations may be provided within biodegradable polymers to reduce, prevent or treat sciatic pain and/or inflammation. In various embodiments, prevent transplant rejection for at least twenty-five days. In some embodiments, the pain relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

Abstract: The device utilizes a thruster cylinder driven by a enlarged knob and terminating in a thruster plate to clamp to a support. Provision is made to attach a device to the clamp through a rotating index wheel which can lock the device by receiving a tang from a trigger lever at a selected increment of rotation. A second embodiment has two index wheels so that the attached device can be displaced in one of four directions to avoid conflict with other devices on the same support. The second axis is normally used to return a displaced device to an upright orientation.

Abstract: The device utilizes a thruster cylinder driven by a enlarged knob and terminating in a thruster plate to clamp to a support. Provision is made to attach a device to the clamp through a rotating index wheel which can lock the device by receiving a tang from a trigger lever at a selected increment of rotation. A second embodiment has two index wheels so that the attached device can be displaced in one of four directions to avoid conflict with other devices on the same support. The second axis is normally used to return a displaced device to an upright orientation.

Abstract: Methods and an apparatus are provided for interpolation of pixels in a pixel array having rows and columns of pixels. The apparatus includes a shift register array to shift pixel values of the pixel array, the shift register array including two or more shift registers; an interpolation filter array interconnected to the shift register array, the interpolation filter array including one or more interpolation filters; and a controller configured to provide pixel values in columns of the pixel array from the shift register array to respective interpolation filters in a first mode and configured to provide pixel values in rows of the pixel array from the shift register array to respective interpolation filters in a second mode. The controller may be configured to supply vertical sub-pixel values from the shift register array to the interpolation filters to generate diagonal sub-pixel values.

Abstract: The present invention is a transparent thermoplastic polyurethane (TPU) comprising structural units of: a.) a diisocyanate; b.1) a polyester diol and b.2) a specific polyether diol and c.) a chain extender. The TPU has good combinations of light transmission and clarity, tensile strength, low temperature flexibility, and high moisture vapor transition rates compared to other commercial or known TPUs. A preferred example composition is a TPU that is based on MDI as the diisocyanate monomer, polycaprolactone as a polyester diol, an EO capped EO/PO polyether diol containing less than 20% EO, and butanediol as chain extender. These composition have good combinations of clarity, tensile strength, hydrolytic stability and processability compared to TPUs prepared using either polyester or polyether diols alone or the combination with a higher EO polyether diol.

Abstract: The stand has modules to form a support base with elongated support members with wheels or legs. The stand can either incorporate two spaced load supporting posts or a single post extending from a spanner module that connects between the elongated support members. When two load support members are employed the user can step between the posts. When a single post and spanner are employed the user can step as far as the spanner near the center of support. The support members diverge from their centers provide a wide stance of the wheels or legs for stability. At the upper end of the post or posts a load support platform is carried either directly on a single post or through a cross-piece on a two post configuration. T-shaped slots in the post can be utilized to attach loads to the posts and a panel extending between posts.

Abstract: The stand has modules to form a support base with elongated support members with wheels or legs. The stand can either incorporate two spaced load supporting posts or a single post extending from a spanner module that connects between the elongated support members. When two load support members are employed the user can step between the posts. When a single post and spanner are employed the user can step as far as the spanner near the center of support. The support members diverge from their centers provide a wide stance of the wheels or legs for stability. At the upper end of the post or posts a load support platform is carried either directly on a single post or through a cross-piece on a two post configuration. T-shaped slots in the post can be utilized to attach loads to the posts and a panel extending between posts.

Abstract: The device utilizes a thruster cylinder driven by a enlarged knob and terminating in a thruster plate to clamp to a support. Provision is made to attach a device to the clamp through a rotating index wheel which can lock the device by receiving a tang from a trigger lever at a selected increment of rotation. A second embodiment has two index wheels so that the attached device can be displaced in one of four directions to avoid conflict with other devices on the same support. The second axis is normally used to return a displaced device to an upright orientation.

Abstract: Effective treatments of pain and/or inflammation for extended periods of time are provided. Through the administration of an effective amount of sulindac or a pharmaceutically acceptable salt thereof at or near a target site, one can relieve pain and/or inflammation caused by diverse sources, including but not limited to spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least three days, at least twenty-five days. In some embodiments, the relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

Abstract: Effective treatments of pain and inflammation are provided. Through the administration of an effective amount of fluocinolone at or near a target site, one can reduce, prevent or treat inflammation and pain and autoimmune disorders. In various embodiments, fluocinolone formulations may be provided within biodegradable polymers to reduce, prevent or treat sciatic pain and/or inflammation. In various embodiments, prevent transplant rejection for at least twenty-five days. In some embodiments, the pain relief can be for at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days.

Abstract: The present invention is a transparent thermoplastic polyurethane (TPU) comprising structural units of: a.) a diisocyanate; b.1) a polyester diol and b.2) a specific polyether diol and c.) a chain extender. The TPU has good combinations of light transmission and clarity, tensile strength, low temperature flexibility, and high moisture vapor transition rates compared to other commercial or known TPUs. A preferred example composition is a TPU that is based on MDI as the diisocyanate monomer, polycaprolactone as a polyester diol, an EO capped EO/PO polyether diol containing less than 20% EO, and butanediol as chain extender. These composition have good combinations of clarity, tensile strength, hydrolytic stability and processability compared to TPUs prepared using either polyester or polyether diols alone or the combination with a higher EO polyether diol.

Abstract: Methods and an apparatus are provided for interpolation of pixels in a pixel array having rows and columns of pixels. The apparatus includes a shift register array to shift pixel values of the pixel array, the shift register array including two or more shift registers; an interpolation filter array interconnected to the shift register array, the interpolation filter array including one or more interpolation filters; and a controller configured to provide pixel values in columns of the pixel array from the shift register array to respective interpolation filters in a first mode and configured to provide pixel values in rows of the pixel array from the shift register array to respective interpolation filters in a second mode. The controller may be configured to supply vertical sub-pixel values from the shift register array to the interpolation filters to generate diagonal sub-pixel values.

Abstract: One example scleral prosthesis includes a first free end and a second free end, each wider than a middle portion of the scleral prosthesis. Multiple first portions form the first end of the scleral prosthesis. The first portions are separated along at least half of a length of the scleral prosthesis. Multiple second portions may form the second end of the scleral prosthesis, and the second portions may be separated along less than a quarter of the length of the scleral prosthesis. An implantation device can be used to facilitate implantation of a scleral prosthesis. The implantation device includes a first end portion configured to be inserted into a scleral tunnel of an eye. The implantation device also includes a second end portion configured to receive the scleral prosthesis. A rod with a tapered and rounded end can be partially inserted into the first end portion of the implantation device.

Abstract: Various ocular fixation devices are disclosed. One ocular fixation device includes first and second rings, where at least one of the rings includes means for fixating ocular tissue of an eye. The means for fixating are arranged to grasp the ocular tissue of the eye and to release the ocular tissue of the eye based on rotation of at least one of the first and second rings. The ocular fixation device may also include one or more structures on which a surgical tool can be mounted on the ocular fixation device at one or more locations. For instance, a dome of the ocular fixation device could include one or more holes that are configured to receive one or more projections from the surgical tool. As another example, a base of the ocular fixation device could include one or more notches configured to receive a projection from the surgical tool.

Abstract: A package in which a dispenser is contained and having at least one support which suspends the dispenser in the package is disclosed. Suspending the dispenser within the package protects it from impacts and deformations of the package, which may otherwise cause it to activate during transit, or if it is provided with a dose-counter, miscount the number of remaining or dispensed.