Patents by Inventor Mark Donnelly

Mark Donnelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150064736
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 5, 2015
    Applicant: DANISCO US INC.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20140141448
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 22, 2014
    Applicant: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 8597901
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: December 3, 2013
    Assignee: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 8216811
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: July 10, 2012
    Assignee: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 7922483
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: April 12, 2011
    Assignee: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 7563609
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: March 18, 2008
    Date of Patent: July 21, 2009
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20080248546
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: March 18, 2008
    Publication date: October 9, 2008
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 7374917
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: May 20, 2008
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 7200640
    Abstract: The present invention discloses a system and method of searching, exploring or otherwise navigating the contents of a collection of networked documents or pages. In a preferred embodiment, this system provides a user with a multimedia display format which intuitively indicates, without the user opening a document or web page, the characteristics of the document or web pages. Additionally, this system permits a user to move between such documents without extensively entering explicit search terms. With this system, the contents of Internet web pages may be evaluated by incrementally adjusting through a multimedia display of a continuum of IP addresses or a continuum of related web pages, which are identified as having keywords that match any of a collection of keywords generated from an initially-inputted keyword. This system further comprises a dial or rotary control that allows the user to select, in a continuous fashion, among such displayed, Internet web pages.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: April 3, 2007
    Inventors: James M. Cole, Mark Donnelly, Medea E. Minnich, William H. Humm
  • Publication number: 20070015245
    Abstract: The present invention provides soluble cytochrome p450 reductase (CPR) proteins from Candida sp. having an altered N-terminal region which results in reduced hydrophobicity of the N-terminal region. Also provided are host cells comprising the subject soluble CPR proteins. In addition, the present invention provides nucleotide and corresponding amino acid sequences for soluble CPR proteins and vectors comprising the nucleotide sequences. Methods for producing a soluble CPR, for increasing production of a dicarboxylic acid, and for detecting a cytochrome P450 are also provided.
    Type: Application
    Filed: June 5, 2006
    Publication date: January 18, 2007
    Inventor: Mark Donnelly
  • Patent number: 7083960
    Abstract: The present invention provides soluble cytochrome p450 reductase (CPR) proteins from Candida sp. having an altered N-terminal region which results in reduced hydrophobicity of the N-terminal region. Also provided are host cells comprising the subject soluble CPR proteins. In addition, the present invention provides nucleotide and corresponding amino acid sequences for soluble CPR proteins and vectors comprising the nucleotide sequences. Methods for producing a soluble CPR, for increasing production of a dicarboxylic acid, and for detecting a cytochrome P450 are also provided.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: August 1, 2006
    Assignee: Cognis Corporation
    Inventor: Mark Donnelly
  • Publication number: 20060099710
    Abstract: A vector designed to include two tags wherein the first tag improves protein expression, folding and solubility, and the second tag promotes affinity purification, and two distinct recognition sequences for highly specific proteases. Uses of the vector include in vivo protein production.
    Type: Application
    Filed: August 3, 2005
    Publication date: May 11, 2006
    Inventors: Mark Donnelly, Andrzej Joachimiak
  • Publication number: 20050158762
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: December 17, 2004
    Publication date: July 21, 2005
    Inventors: Mark Donnelly, William Eschenfeldt, Jonathan Trent
  • Patent number: 6864075
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: March 8, 2005
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20050050163
    Abstract: The present invention discloses a system and method of searching, exploring or otherwise navigating the contents of a collection of networked documents or pages. In a preferred embodiment, this system provides a user with a multimedia display format which intuitively indicates, without the user opening a document or web page, the characteristics of the document or web pages. Additionally, this system permits a user to move between such documents without extensively entering explicit search terms. With this system, the contents of Internet web pages may be evaluated by incrementally adjusting through a multimedia display of a continuum of related web pages, which are identified as having keywords that match any of a collection of keywords generated from an initially-inputted keyword. This system further comprises a dial or rotary control that allows the user to select, in a continuous fashion, among such displayed, Internet web pages.
    Type: Application
    Filed: September 28, 2004
    Publication date: March 3, 2005
    Inventors: James Cole, Medea Minnich, William Humm, Mark Donnelly, Susan Donnelly
  • Publication number: 20040077038
    Abstract: The present invention provides methods for the production of proteins, particularly toxic proteins, in host cells. The invention provides methods which use a fusion protein comprising a chaperonin binding domain in host cells induced or regulated to have increased levels of chaperonin which binds the chaperonin binding domain.
    Type: Application
    Filed: November 13, 2003
    Publication date: April 22, 2004
    Inventors: Mark Donnelly, Andrzej Joachimiak
  • Patent number: 6677139
    Abstract: The present invention provides methods for the production of proteins, particularly toxic proteins, in host cells. The invention provides methods which use a fusion protein comprising a chaperonin binding domain in host cells induced or regulated to have increased levels of chaperonin which binds the chaperonin binding domain.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: January 13, 2004
    Assignee: Genecor International, Inc.
    Inventors: Mark Donnelly, Andrzej Joachimiak
  • Publication number: 20030203449
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: April 17, 2003
    Publication date: October 30, 2003
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20030119145
    Abstract: The present invention provides soluble cytochrome p450 reductase (CPR) proteins from Candida sp. having an altered N-terminal region which results in reduced hydrophobicity of the N-terminal region. Also provided are host cells comprising the subject soluble CPR proteins. In addition, the present invention provides nucleotide and corresponding amino acid sequences for soluble CPR proteins and vectors comprising the nucleotide sequences. Methods for producing a soluble CPR, for increasing production of a dicarboxylic acid, and for detecting a cytochrome P450 are also provided.
    Type: Application
    Filed: October 15, 2002
    Publication date: June 26, 2003
    Inventor: Mark Donnelly
  • Patent number: 6576452
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: June 10, 2003
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent