Patents by Inventor Mark E Cook

Mark E Cook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170119016
    Abstract: Described herein are methods of use of purified preen oil, food and feed compositions containing purified preen oil, food and feed additives containing purified preen oil, and pharmaceutical compositions containing purified preen oil. Methods include treatment of chronic joint inflammation in humans and animals by orally administering purified preen oil. Also included are methods of feeding a growing fish by feeding the feeding the growing fish purified preen oil in amounts effective to improve survival and/or stimulate growth in the growing fish. Further included are methods of feeding live prey organisms purified preen oil, and feeding the live prey organisms to growing fish.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 4, 2017
    Inventors: MARK E. COOK, JORDAN SAND, JAKE M. OLSON, TERENCE P. BARRY
  • Publication number: 20160318994
    Abstract: Described herein are methods of preventing and/or treating inflammation in a barrier surface structure in an individual in need thereof by orally administering to the individual an anti-inflammatory amount of secretory IgA.
    Type: Application
    Filed: July 13, 2016
    Publication date: November 3, 2016
    Inventors: Mark E. Cook, Jordan Marshall Sand, Lisa Ann Krugner-Higby, James Mukasa Ntambi
  • Patent number: 9468674
    Abstract: Described herein are methods of preventing and/or treating inflammation in a barrier surface structure in an individual in need thereof by orally administering to the individual an anti-inflammatory amount of secretory IgA.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: October 18, 2016
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Mark E. Cook, Jordan Marshall Sand, Lisa Ann Krugner-Higby, James Mukasa Ntambi
  • Publication number: 20150266921
    Abstract: Disclosed are methods of altering metabolism of phosphate in a livestock via an antibody. The methods involve the development of an antibody against FGF-23 for the purpose of reducing phosphate excretion by an animal.
    Type: Application
    Filed: June 10, 2015
    Publication date: September 24, 2015
    Inventors: Mark E. Cook, Elizabeth A. Bobeck, Kimberly S. Burgess
  • Patent number: 9092995
    Abstract: A medical training device with an improved clam shell type torso arrangement. An improved two-piece tiltable head feature, including mechanical mounting structure for secure attachment of an improved lung bag or face shield. The head also includes an improved nose feature to provide a more realistic representation of nasal cartilage, and an improved neck assembly. Additionally, an electro-mechanical indicator device is provided to show real time feedback of the CPR compression rate being administered by a student on the training manikin of the present application. The feedback by the device may be provided preferably by visual indicators, but may also have, or alternatively have, audio indicators or signals, such as words or sounds, to indicate whether or not the student is compressing within the preferred rate range, and/or the degree of variance in the student's compression sequences.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: July 28, 2015
    Assignee: Prestan Products LLC
    Inventors: John J Pastrick, Christopher E Bryniarski, Mark E Cook, Timothy E Lint
  • Publication number: 20150196248
    Abstract: Described herein are methods of determining energy balance in individuals such as exercising individuals, individuals consuming a 13C-enriched test composition and individuals consuming a fixed diet with a known ?13C. The ?13C pre- and post-exercise, or pre- and post-consumption of the test beverage or fixed diet indicate whether the individual is in neutral or positive energy balance, or in energy deficit. The methods are particularly useful for individuals participating in weight management programs, and individuals under the care of health care professionals.
    Type: Application
    Filed: January 10, 2014
    Publication date: July 16, 2015
    Inventors: Mark E. Cook, Leah D. Whigham, Daniel Elmer Butz, Warren Paul Porter, David H. Abbott, Dale A. Schoeller
  • Patent number: 9078842
    Abstract: Disclosed are methods of altering metabolism of phosphate in a livestock via an antibody. The methods involve the development of an antibody against FGF-23 for the purpose of reducing phosphate excretion by an animal.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: July 14, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark E. Cook, Elizabeth A. Bobeck, Kimberly S. Burgess
  • Publication number: 20150125840
    Abstract: A portable medical training manikin with a hollow torso body with a chest plate having slotted openings provided to enable realistic flexing of the chest plate along hinges engaged with a chest compression piston. The torso body has a realistic skin covering the torso and interconnected at a hinge. A chest compression piston supports and resists chest compressions performed by a user. The chest compression piston is engaged with the central chest plate of the torso body by a quick release mechanism having detent locks for securing the piston engaged with the chest plate. A two-piece tiltable head configuration enables detachment of the back half of the head piece, and inversion for nested stacking within the front half head piece. The hollow torso body is likewise configured for convenient stacking, including the compression pistons, in a carrying container.
    Type: Application
    Filed: November 7, 2013
    Publication date: May 7, 2015
    Applicant: PRESTAN PRODUCTS LLC
    Inventors: John J. Pastrick, Christopher E. Bryniarski, Mark E. Cook, Timothy E. Lint, Daniel R. Moon
  • Publication number: 20150086534
    Abstract: Described herein are methods of preventing and/or treating inflammation in a barrier surface structure in an individual in need thereof by orally administering to the individual an anti-inflammatory amount of secretory IgA.
    Type: Application
    Filed: September 24, 2013
    Publication date: March 26, 2015
    Inventors: Mark E. Cook, Jordan Marshall Sand, Lisa Ann Krugner-Higby, James Mukasa Ntambi
  • Patent number: 8852117
    Abstract: Methods are disclosed for distinguishing whether an animal is experiencing a bacterial infection or a viral infection. One monitors breath taken from the animal over time to measure the relative amount of a first breath stable isotope to a second breath stable isotope therein over time. A quick change in the isotope ratios within several hours from the likely infection is indicative of a bacterial infection. A delayed change in the isotope ratios, followed by periodic repeated alterations in the ratios, is indicative of viral infection. The methods are particularly efficient when using cavity ringdown spectroscopy for the monitoring. They may be used for monitoring a patient already admitted to a hospital, or for monitoring a patient initially complaining of adverse symptoms, or for triage, or for collectively monitoring a population of animals.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: October 7, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Fariba M. Assadi-Porter, Mark E. Cook, Warren P. Porter, Daniel E. Butz
  • Publication number: 20140170622
    Abstract: An improved training pad connector device for connecting a disposable electrode training pad to an electrical cable using a very low profile, approximately 0.16 of an inch, which does not interrupt the external surface or dimensions of the training pad. The connector includes a top piece and a bottom piece forming a unitary body for capturing the electrical contacts and extending cable between the interconnected top and bottom pieces, and for engaging the electrode training pad on an extending tab. The top and bottom pieces of the connector and the electrode training pad each include aligned openings for receiving a removable pin. The removable pin engages the connector in an interference fit to secure the pad and connector together.
    Type: Application
    Filed: September 11, 2013
    Publication date: June 19, 2014
    Inventors: John J. Pastrick, Timothy E. Lint, Mark E. Cook
  • Publication number: 20130236925
    Abstract: The methods described herein are based on the observation that oscillations in breath isotope ratio data can be used for the purpose of identifying an “unhealthy” state in an organism such as a human. Described herein are methods of determining the state of health of an individual, such as the transition from healthy to infected, by identifying changes in oscillation modes in breath isotope ratio data. Changes in the frequency and/or amplitude of the oscillation modes are correlated with the heath of the individual. The methods can advantageously be used to provide information about the health of an individual in shorter periods of time than previous methods.
    Type: Application
    Filed: March 7, 2012
    Publication date: September 12, 2013
    Inventors: Hamid R. Eghbalnia, Mark E. Cook, Warren Paul Porter, Daniel Elmer Butz
  • Patent number: 8512676
    Abstract: The methods described herein are based on the observation that oscillations in breath isotope ratio data can be used for the purpose of identifying an “unhealthy” state in an organism such as a human. Described herein are methods of determining the state of health of an individual, such as the transition from healthy to infected, by identifying changes in oscillation modes in breath isotope ratio data. Changes in the frequency and/or amplitude of the oscillation modes are correlated with the heath of the individual. The methods can advantageously be used to provide information about the health of an individual in shorter periods of time than previous methods.
    Type: Grant
    Filed: March 7, 2012
    Date of Patent: August 20, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Hamid R. Eghbalnia, Mark E. Cook, Warren Paul Porter, Daniel Elmer Butz
  • Patent number: 8465293
    Abstract: A medical training device with an improved clam shell type torso arrangement. An improved two-piece tiltable head feature, including mechanical mounting structure for secure attachment of an improved lung bag or face shield. The head also includes an improved nose feature to provide a more realistic representation of nasal cartilage, and an improved neck assembly. Additionally, an electro-mechanical indicator device is provided to show real time feedback of the CPR compression rate being administered by a student on the training manikin of the present application. The feedback by the device may be provided preferably by visual indicators, but may also have, or alternatively have, audio indicators or signals, such as words or sounds, to indicate whether or not the student is compressing within the preferred rate range, and/or the degree of variance in the student's compression sequences.
    Type: Grant
    Filed: May 19, 2010
    Date of Patent: June 18, 2013
    Assignee: Prestan Products LLC
    Inventors: John J. Pastrick, Mark E. Cook, Timothy E. Lint, Christopher E. Bryniarski
  • Patent number: 8435187
    Abstract: Methods are disclosed for distinguishing whether an animal is experiencing a bacterial infection or a viral infection. One monitors breath taken from the animal over time to measure the relative amount of a first breath stable isotope to a second breath stable isotope therein over time. A quick change in the isotope ratios within several hours from the likely infection is indicative of a bacterial infection. A delayed change in the isotope ratios, followed by periodic repeated alterations in the ratios, is indicative of viral infection. The methods are particularly efficient when using cavity ringdown spectroscopy for the monitoring. They may be used for monitoring a patient already admitted to a hospital, or for monitoring a patient initially complaining of adverse symptoms, or for triage, or for collectively monitoring a population of animals.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: May 7, 2013
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Fariba M. Assadi-Porter, Mark E. Cook, Warren P. Porter, Daniel E. Butz
  • Publication number: 20130066224
    Abstract: Methods are disclosed for distinguishing whether an animal is experiencing a bacterial infection or a viral infection. One monitors breath taken from the animal over time to measure the relative amount of a first breath stable isotope to a second breath stable isotope therein over time. A quick change in the isotope ratios within several hours from the likely infection is indicative of a bacterial infection. A delayed change in the isotope ratios, followed by periodic repeated alterations in the ratios, is indicative of viral infection. The methods are particularly efficient when using cavity ringdown spectroscopy for the monitoring. They may be used for monitoring a patient already admitted to a hospital, or for monitoring a patient initially complaining of adverse symptoms, or for triage, or for collectively monitoring a population of animals.
    Type: Application
    Filed: November 8, 2012
    Publication date: March 14, 2013
    Inventors: Fariba M. Assadi-Porter, Mark E. Cook, Warren P. Porter, Daniel E. Butz
  • Patent number: 8026049
    Abstract: The invention is methods and related kits for diagnosing a disease state of cachexia by measuring biomarker profiles from a biological sample. Rapid measurement of early onset or progression of the disease in a subject is determined by measuring biomarker levels from the subject and optionally comparing the biomarker levels to a standard biomarker profile or metabolome phase portrait for the disease. The biomarkers measured in the assay and related kit for cachexia progression include biomarkers selected from the group consisting of lactate, citrate, formate, acetoacetate, 3-hydroxy butrate, alanine, glutamine, glutamate, valine, isoleucine leucine, thrionine, lysine, arginine, tyrosine, phenyl alanine, histidine and tryptophan.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: September 27, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Fariba Masoumeh Assadi-Porter, Mark E. Cook, Hamid Reza Eghbalnia, Marco Tonelli, Warren Paul Porter, Daniel Elmer Butz
  • Publication number: 20110086045
    Abstract: A method for reducing gastrointestinal inflammation, enhancing growth, or improving feed efficiency in a human or non-human animal is disclosed. The method involves administering to the animal an agent that can reduce the formation of the signal transduction complex of endotoxin, TLR4 and CD14 on the cellular surface of a cell in the gastrointestinal tract of the animal. In a preferred embodiment, an antibody against the extracellular domain of TLR4 or CD14 is used to reduce the formation of the complex. A composition that contains the antibody and an ingestible carrier is also disclosed. Further disclosed is a method for producing a peptide for enhancing growth, improving feed efficiency, or both in a human or non-human animal.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 14, 2011
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Mark E. Cook, Mingder Yang, David M. Barnes
  • Patent number: D690818
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: October 1, 2013
    Assignee: Prestan Products LLC
    Inventors: John J. Pastrick, Christopher E. Bryniarski, Mark E. Cook, Timothy E. Lint, Daniel R. Moon
  • Patent number: D717444
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: November 11, 2014
    Assignee: Preston Products LLC
    Inventors: John J. Pastrick, Christopher E. Bryniarski, Mark E. Cook, Timothy E. Lint, Daniel R. Moon