Patents by Inventor Mark E Cook

Mark E Cook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7896603
    Abstract: A trailer (10) or container (11) includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carriage assembly (24) rotates the plurality of storage supports. A powered drive (110) rotates the carriage assembly. A powered restrictor (120) limits rotational movement of a respective carriage support during transit. Flexible members 142 and 144 interconnect the drive member and driven members each mounted with respect to a storage support. The container may be transported on a motorized vehicle. A preferred tire support mechanism is provided for use when transporting tires.
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: March 1, 2011
    Inventor: Mark E. Cook
  • Patent number: 7883701
    Abstract: A method for reducing gastrointestinal inflammation, enhancing growth, or improving feed efficiency in a human or non-human animal is disclosed. The method involves administering to the animal an agent that can reduce the formation of the signal transduction complex of endotoxin, TLR4 and CD14 on the cellular surface of a cell in the gastrointestinal tract of the animal. In a preferred embodiment, an antibody against the extracellular domain of TLR4 or CD14 is used to reduce the formation of the complex. A composition that contains the antibody and an ingestible carrier is also disclosed. Further disclosed is a method for producing a peptide for enhancing growth, improving feed efficiency, or both in a human or non-human animal.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: February 8, 2011
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark E. Cook, Mingder Yang, David M. Barnes
  • Publication number: 20100291522
    Abstract: A medical training device with an improved clam shell type torso arrangement. An improved two-piece tiltable head feature, including mechanical mounting structure for secure attachment of an improved lung bag or face shield. The head also includes an improved nose feature to provide a more realistic representation of nasal cartilage, and an improved neck assembly. Additionally, an electro-mechanical indicator device is provided to show real time feedback of the CPR compression rate being administered by a student on the training manikin of the present application. The feedback by the device may be provided preferably by visual indicators, but may also have, or alternatively have, audio indicators or signals, such as words or sounds, to indicate whether or not the student is compressing within the preferred rate range, and/or the degree of variance in the student's compression sequences.
    Type: Application
    Filed: May 19, 2010
    Publication date: November 18, 2010
    Applicant: PRESTAN PRODUCTS LLC
    Inventors: Mark E. Cook, Timothy E. Lint, Christopher E. Bryniarski, John J. Pastrick
  • Patent number: 7750117
    Abstract: It is disclosed here that a protein with a heat-labile specific binding activity can be stabilized with a saccharide compound with regard to the binding activity. To heat-stabilize the protein, it is mixed with a saccharide compound in a liquid suspension and the suspension is then dried to produce a solid that contains the protein and the saccharide. The saccharide compounds that possess the protein heat-stabilization activity include monosaccharides, disaccharides, polysaccharides, alkylated monosaccharides, alkylated disaccharides, alkylated polysaccharides, monosaccharide alcohols and alkylated monosaccharide alcohols.
    Type: Grant
    Filed: February 11, 2004
    Date of Patent: July 6, 2010
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark E. Cook, Mingder Yang, Mark R. Etzel
  • Publication number: 20100036274
    Abstract: Methods are disclosed for distinguishing whether an animal is experiencing a bacterial infection or a viral infection. One monitors breath taken from the animal over time to measure the relative amount of a first breath stable isotope to a second breath stable isotope therein over time. A quick change in the isotope ratios within several hours from the likely infection is indicative of a bacterial infection. A delayed change in the isotope ratios, followed by periodic repeated alterations in the ratios, is indicative of viral infection. The methods are particularly efficient when using cavity ringdown spectroscopy for the monitoring. They may be used for monitoring a patient already admitted to a hospital, or for monitoring a patient initially complaining of adverse symptoms, or for triage, or for collectively monitoring a population of animals.
    Type: Application
    Filed: October 20, 2008
    Publication date: February 11, 2010
    Inventors: Fariba M. Assadi-Porter, Mark E. Cook, Warren P. Porter, Daniel E. Butz
  • Patent number: 7579002
    Abstract: A method for improving animal body weight uniformity or for increasing animal carcass yield is disclosed. The method involves administering an agent to one or a group of animals wherein the agent can reduce bioavailability of a prostaglandin or leukotriene lipid precursor. In a preferred embodiment, the agent employed is an anti-PLA2 antibody.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: August 25, 2009
    Assignees: Wisconsin Alumni Research Foundation, Michigan State University
    Inventors: Mark E. Cook, Mingder Yang, Kevin Roberson
  • Publication number: 20090104596
    Abstract: The invention is methods and related kits for diagnosing a disease state of cachexia by measuring biomarker profiles from a biological sample. Rapid measurement of early onset or progression of the disease in a subject is determined by measuring biomarker levels from the subject and optionally comparing the biomarker levels to a standard biomarker profile or metabolome phase portrait for the disease. The biomarkers measured in the assay and related kit for cachexia progression include biomarkers selected from the group consisting of lactate, citrate, formate, acetoacetate, 3-hydroxy butrate, alanine, glutamine, glutamate, valine, isoleucine leucine, thrionine, lysine, arginine, tyrosine, phenyl alanine, histidine and tryptophan.
    Type: Application
    Filed: March 24, 2008
    Publication date: April 23, 2009
    Inventors: Fariba Masoumeh Assadi-Porter, Mark E. Cook, Hamid Reza Eghbalnia, Marco Tonelli, Warren Paul Porter, Daniel Elmer Butz
  • Publication number: 20090092639
    Abstract: Methods and compositions for increasing antibody titer in egg yolks and for using the antibodies are disclosed.
    Type: Application
    Filed: December 17, 2008
    Publication date: April 9, 2009
    Inventors: Mark E. Cook, David L. Trott, Mingder Yang
  • Patent number: 7465276
    Abstract: Methods are disclosed for distinguishing whether an animal is experiencing a bacterial infection or a viral infection. One monitors breath taken from the animal over time to measure the relative amount of a first breath stable isotope to a second breath stable isotope therein over time. A quick change in the isotope ratios within several hours from the likely infection is indicative of a bacterial infection. A delayed change in the isotope ratios, followed by periodic repeated alterations in the ratios, is indicative of viral infection. The methods are particularly efficient when using cavity ringdown spectroscopy for the monitoring. They may be used for monitoring a patient already admitted to a hospital, or for monitoring a patient initially complaining of adverse symptoms, or for triage, or for collectively monitoring a population of animals.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: December 16, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Fariba M. Assadi-Porter, Mark E. Cook, Warren P. Porter, Daniel E. Butz
  • Publication number: 20080286079
    Abstract: A trailer (10) or container (11) includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carriage assembly (24) rotates the plurality of storage supports. A powered drive (110) rotates the carriage assembly. A powered restrictor (120) limits rotational movement of a respective carriage support during transit. Flexible members 142 and 144 interconnect the drive member and driven members each mounted with respect to a storage support. The container may be transported on a motorized vehicle. A preferred tire support mechanism is provided for use when transporting tires.
    Type: Application
    Filed: May 22, 2008
    Publication date: November 20, 2008
    Inventor: Mark E. Cook
  • Publication number: 20080102067
    Abstract: Methods and compositions for increasing antibody titer in egg yolks and for using the antibodies are disclosed.
    Type: Application
    Filed: October 25, 2006
    Publication date: May 1, 2008
    Inventors: Mark E. Cook, David L. Trott, Mingder Yang
  • Publication number: 20080089769
    Abstract: A trailer 10 includes a frame (12) having a central axis (14) spaced between rear wheels. A plurality of storage supports (20) are supported on the trailer frame, with each storage support supporting a plurality of objects thereon. A carriage assembly (24) rotates the plurality of storage supports. A powered drive (110) rotates the carriage assembly, and a powered brake (112) prohibits rotation of the carriage assembly when power is not applied to the motor. The power restrictor (120) limits axial movement of a respective carriage support during transit.
    Type: Application
    Filed: October 3, 2007
    Publication date: April 17, 2008
    Inventor: Mark E. Cook
  • Patent number: 7083909
    Abstract: A composition that contains a gamete or an embryo and animal white yolk is disclosed. Also disclosed are applications of the composition.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: August 1, 2006
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Jackie J. Rutledge, Mark E. Cook, Ricky L. Monson, Crague E. Cook, Niels Jorgensen
  • Patent number: 6908946
    Abstract: The present invention provides a method of using conjugated nonadecadienoic acid (CNA), one of its derivatives, or a combination thereof to inhibit lipoprotein lipase activity associated with a cell, to control body fat in a human or non-human animal, to inhibit cyclooxygenase activity in a cell, to inhibit platelet aggregation in a human or non-human animal, and to prevent or treat a condition or disease related to platelet aggregation.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: June 21, 2005
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark E. Cook, Michael W Pariza, Yeonhwa Park, Guangming Li
  • Publication number: 20030217380
    Abstract: A composition that contains a gamete or an embryo and animal white yolk is disclosed. Also disclosed are applications of the composition.
    Type: Application
    Filed: March 13, 2003
    Publication date: November 20, 2003
    Inventors: Jackie J. Rutledge, Mark E. Cook, Ricky L. Monson, Crague E. Cook, Niels Jorgensen
  • Publication number: 20030133923
    Abstract: A digestive system bezoar in a human or non-human animal susceptible to bezoar formation can be reduced in size by administering to the animal a food grade agent for emulsifying fat in an amount sufficient to reduce the size of the bezoar so that the bezoar can pass out of the animal's digestive system. In a similar method for preventing bezoar formation in a human or non-human animal susceptible to bezoar formation, a food grade agent for emulsifying fat can be administered to the animal in an amount sufficient to prevent formation of bezoars, or at least to prevent formation of bezoars larger than a size that becomes trapped in the animal's digestive system.
    Type: Application
    Filed: March 14, 2003
    Publication date: July 17, 2003
    Inventors: Mark E. Cook, Beth M. Drake, Leonard S. Girsh, Janet R. Jackson
  • Patent number: 6562366
    Abstract: A digestive system bezoar in a human or non-human animal susceptible to bezoar formation can be reduced in size by administering to the animal a food grade agent for emulsifying fat in an amount sufficient to reduce the size of the bezoar so that the bezoar can pass out of the animal's digestive system. In a similar method for preventing bezoar formation in a human or non-human animal susceptible to bezoar formation, a food grade agent for emulsifying fat can be administered to the animal in an amount sufficient to prevent formation of bezoars, or at least to prevent formation of bezoars larger than a size that becomes trapped in the animal's digestive system.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: May 13, 2003
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark E. Cook, Beth M. Drake, Leonard S. Girsh, Janet R. Jackson
  • Publication number: 20030008845
    Abstract: The present invention provides a method of using conjugated nonadecadienoic acid (CNA), one of its derivatives, or a combination thereof to inhibit lipoprotein lipase activity associated with a cell, to control body fat in a human or non-human animal, to inhibit cyclooxygenase activity in a cell, to inhibit platelet aggregation in a human or non-human animal, and to prevent or treat a condition or disease related to platelet aggregation.
    Type: Application
    Filed: May 31, 2002
    Publication date: January 9, 2003
    Inventors: Mark E. Cook, Michael W. Pariza, Yeonhwa Park, Guangming Li
  • Publication number: 20020182202
    Abstract: A digestive system bezoar in a human or non-human animal susceptible to bezoar formation can be reduced in size by administering to the animal a food grade agent for emulsifying fat in an amount sufficient to reduce the size of the bezoar so that the bezoar can pass out of the animal's digestive system. In a similar method for preventing bezoar formation in a human or non-human animal susceptible to bezoar formation, a food grade agent for emulsifying fat can be administered to the animal in an amount sufficient to prevent formation of bezoars, or at least to prevent formation of bezoars larger than a size that becomes trapped in the animal's digestive system.
    Type: Application
    Filed: April 20, 2001
    Publication date: December 5, 2002
    Inventors: Mark E. Cook, Beth M. Drake, Leonard S. Girsh, Janet R. Jackson
  • Patent number: D466215
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: November 26, 2002
    Assignee: Complient Corporation
    Inventors: Steven W. Lindseth, R. Richard Carpenter, John J. Pastrick, Kyle Swen, Brett Lovelady, Mark E. Cook, Curt Bingham