Abstract: A structure directing agent is removed from a microporous solid at a temperature below the temperature that would cause the structure directing agent to decompose by cleaving the structure directing agent within the pores of the microporous solid, at a temperature below the temperature that would cause the structure directing agent to decompose, into two or more fragments and removing the fragments from the pores of the microporous solid at a temperature below the temperature that would cause the structure directing agent or its fragments to decompose.

Abstract: The invention provides methods of identifying one or more nucleic acids in a sample. The nucleic acids, for example, expressed genes in a cell, can be identified by contacting the nucleic acids with oligonucleotides having detector tags, and selector tags to form tagged oligonucleotides. Each nucleic acid can be uniquely identified by mass-spectrophotometric analysis of the detector tag.

Abstract: The present invention relates to new crystalline, molecular sieve CIT-6 that has the topology of zeolite beta. CIT-6 can be in an all-silica form, in a form wherein zinc is in the crystal framework, or a form containing silicon oxide and non-silicon oxides. In a preferred embodiment, CIT-6 has a crystal size of less than one micron and a water adsorption capacity of less than 0.05 g/g.

Abstract: The present invention relates to new crystalline, molecular sieve CIT-6 that has the topology of zeolite beta. CIT-6 can be in an all-silica form, in a form wherein zinc is in the crystal framework, or a form containing silicon oxide and non-silicon oxides. In a preferred embodiment, CIT-6 has a crystal size of less than one micron and a water adsorption capacity of less than 0.05 g/g.

Abstract: A machine for automatically applying lane dressing travels up and down the lane to apply dressing according to a certain predetermined and preselected pattern. A single dispensing head travels back and forth across the lane as the machine moves linearly along the lane so that dressing is transferred to a buffer brush that engages the lane surface and applies the dressing thereto. The oil pattern is determined by actuation and deactuation of the dispensing head as it traverses the lane, such control of the head being provided by a special pattern control device in the nature of a cylindrical pattern tube that extends alongside the path of travel of the dispensing head. A sensor on the dispensing head detects pattern structure on the control device to responsively actuate and deactuate the head. In a preferred form, such structure takes the form of a series of metallic strips extending parallel to the path of travel of the dispensing head and spaced circumferentially around the periphery of the pattern tube.

Abstract: This application discloses cyclodextrin-modified materials for carrying drugs and other active agents, such as nucleic acids. Compositions are also disclosed of cyclodextrin-modified materials that release such active agents under controlled conditions. The invention also discloses compositions of cyclodextrin-modified polymer carriers that are coupled to biorecognition molecules for assisting the delivery of drugs to their site of action.

Abstract: This application discloses compositions of carbohydrate-modified polymers, such as polyethylenimine modified with cyclodextrin moieties, for carrying drugs and other active agents, such as nucleic acids. Compositions are also disclosed of carbohydrate-modified polymer carriers that release such agents under controlled conditions. The invention also discloses compositions of carbohydrate-modified polymer carriers that are coupled to biorecognition molecules for targeting the delivery of drugs to their site of action.

Abstract: The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein.

Abstract: The present invention provides methods and compositions for attenuating expression of a target gene in vivo. In general, the method includes administering RNAi constructs (such as small-interfering RNAs (i.e., siRNAs) that are targeted to particular mRNA sequences, or nucleic acid material that can produce siRNAs in a cell), in an amount sufficient to attenuate expression of a target gene by an RNA interference mechanism, e.g., in a sequence-dependent, PKR-independent manner. In particular, the subject method can be used to alter the growth, survival or differentiation of cells for therapeutic and cosmetic purposes.

Abstract: A structure directing agent is removed from a microporous solid at a temperature below the temperature that would cause the structure directing agent to decompose by cleaving the structure directing agent within the pores of the microporous solid, at a temperature below the temperature that would cause the structure directing agent to decompose, into two or more fragments and removing the fragments from the pores of the microporous solid at a temperature below the temperature that would cause the structure directing agent or its fragments to decompose.

Abstract: A lane maintenance machine having wicks that absorb dressing from a reservoir and transfer it to the applicator of the machine has a gravity-fed dressing supply system that maintains the dressing at a substantially constant level within the wick reservoir. A small pilot chamber upstream from the reservoir and in open communication therewith at the same elevation as the reservoir has its fluid level directly controlled by a float sensor to in turn indirectly control the level within the wick reservoir. The float sensor within the pilot chamber provides a signal to a controller when the level within the pilot chamber drops below a predetermined point so that a control valve between the pilot chamber and the main supply tank opens to allow a makeup volume of dressing to flow by gravity from the main tank into the pilot chamber.

Abstract: A machine for automatically applying lane dressing travels up and down the lane to apply dressing according to a certain predetermined and preselected pattern. A single dispensing head travels back and forth across the lane as the machine moves linearly along the lane so that dressing is transferred to a buffer brush that engages the lane surface and applies the dressing thereto. The oil pattern is determined by actuation and deactuation of the dispensing head as it traverses the lane, such control of the head being provided by a special pattern control device in the nature of a cylindrical pattern tube that extends alongside the path of travel of the dispensing head. A sensor on the dispensing head detects pattern structure on the control device to responsively actuate and deactuate the head. In a preferred form, such structure takes the form of a series of metallic strips extending parallel to the path of travel of the dispensing head and spaced circumferentially around the periphery of the pattern tube.

Abstract: A rollable sports ballast base for supporting a sports apparatus support member comprising a base member which has a first edge and a second edge, a top surface and a bottom surface. The bottom surface is adapted to contact a support surface such as a driveway or other playing surface. There is at least one wheel assembly for contacting the support surface. One of the wheel assemblies is retractable from a lowered position to a raised position such that when in the raised position, the bottom surface of the base member substantially contacts the support surface. In the lowered position, both wheel assemblies contact the support surface thereby separating or elevating the base member from the support surface. In another embodiment, the invention consists of a similar rollable sports base for supporting a sports apparatus support member wherein one wheel assembly is retractable and comprises a pivoting connector coupled to the base member and a wheel bracket coupled to the pivoting connector.

Abstract: An outdoor fireplace including a combustion chamber that has a top portion and an ash pan. The top portion and said ash pan are rigidly connected by a plurality of substantially vertical supports. The outdoor fireplace further includes a base, the base providing an upper portion and a support structure. The upper portion substantially spans the area spanned by the ash pan and is connected to the ash pan such that an integral airway is formed between the ash pan and the upper portion.

Abstract: As the cleaning machine travels along the lane from the foul line toward the pin deck area, cleaning liquid is sprayed onto the lane surface in periodic discharges of relatively short duration. A soft, thin web of cloth material immediately behind the spray nozzles is looped under a transverse cushion or backup member and is pressed against the wetted lane surface to spread and meter out the liquid into a thin film that passes beneath the cushion as a bead or shallow pool of the liquid is pushed along ahead of the cushion. The film is subsequently lifted entirely off the lane surface to remove all traces of moisture, oil, and grime by a combination squeegee and vacuum head assembly immediately behind the spreading web assembly. Programmable controls on the machine permit the cleaning functions to be carried out in relation to the position of the machine on the lane.

Abstract: The present invention provides methods and compositions for attenuating expression of a target gene in vivo. In general, the method includes administering RNAi constructs (such as small-interfering RNAs (i.e., siRNAs) that are targeted to particular mRNA sequences, or nucleic acid material that can produce siRNAs in a cell), in an amount sufficient to attenuate expression of a target gene by an RNA interference mechanism, e.g., in a sequence-dependent, PKR-independent manner. In particular, the subject method can be used to alter the growth, survival or differentiation of cells for therapeutic and cosmetic purposes.

Abstract: An active and selective hydrocarbon partial oxidation catalyst comprises an activated partially-reduced polyoxometallate, preferably niobium polyoxomolybdate, that is prepared from a suitable polyoxoanion, which has been exchanged with a suitable cation and activated by heating to an activation effective temperature in the presence of a suitable reducing agent such as pyridinium. C3 and C4 hydrocarbons may be partially oxidized selectively to acrylic acid and maleic acid.

Abstract: A lane maintenance machine having wicks that absorb dressing from a reservoir and transfer it to the applicator of the machine has a gravity-fed dressing supply system that maintains the dressing at a substantially constant level within the wick reservoir. A small pilot chamber upstream from the reservoir and in open communication therewith at the same elevation as the reservoir has its fluid level directly controlled by a float sensor to in turn indirectly control the level within the wick reservoir. The float sensor within the pilot chamber provides a signal to a controller when the level within the pilot chamber drops below a predetermined point so that a control valve between the pilot chamber and the main supply tank opens to allow a makeup volume of dressing to flow by gravity from the main tank into the pilot chamber.

Abstract: The present invention relates to new crystalline, molecular sieve CIT-6 that has the topology of zeolite beta. CIT-6 can be in an all-silica form, in a form wherein zinc is in the crystal framework, or a form containing silicon oxide and non-silicon oxides. In a preferred embodiment, CIT-6 has a crystal size of less than one micron and a water adsorption capacity of less than 0.05 g/g.