Abstract: Particular embodiments described herein provide for modular device assemblies and methods for enabling maintenance and servicing, particularly by an unmanned aerial vehicle. A device assembly comprises a plurality of modules, each module having control circuitry, a communications port and contact points to couple the modules. When the modules are coupled, the communications ports are connected to create a bus for communications between the modules. The modular device structure where modules are removable and replaceable allows for an unmanned aerial vehicle to perform maintenance on the device.

Abstract: Particular embodiments described herein provide for modular device assemblies and methods for enabling maintenance and servicing, particularly by an unmanned aerial vehicle. A device assembly comprises a plurality of modules, each module having control circuitry, a communications port and contact points to couple the modules. When the modules are coupled, the communications ports are connected to create a bus for communications between the modules. The modular device structure where modules are removable and replaceable allows for an unmanned aerial vehicle to perform maintenance on the device.

Abstract: There is disclosed in an example, a pourable smart matter having a plurality of compute nodes, the compute nodes having: a mechanical structure having a plurality of faces, the faces having abutting face detectors; a network interface; and one or more logic elements comprising a positional engine to: identify a neighbor compute node abutting at least one of the faces; and build an individual positional profile based at least in part on the identifying. The pourable smart matter may be used, for example, to determine the geometry or volume of a container.

Abstract: Systems and methods are disclosed for managing logistics information related to a container using a container interface display apparatus. A scanner on the container interface display apparatus identifies an item during loading of the container. An association between the container and the item is recorded in memory of the container interface display apparatus as part of managed logistics information related to the container. A scale within the container detects a weight of the item and sends a signal to the container interface display apparatus indicating the detected weight of the item (which is also recorded in memory as part of the managed logistics information related to the container). Electronic logistics monitor information (e.g., at least a portion of the managed logistics information) is then generated on the display screen of the container interface display apparatus.

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.

Abstract: Methods, apparatus, and systems are described for generating a content related notification based upon managed logistics information related to a container using a container interface display apparatus. Such a container interface display apparatus records an update to the managed logistics information maintained in a memory of the container interface display apparatus and then accesses at least a portion of the managed logistics information maintained in the memory after recording the update. The container interface display apparatus then detects a notification event based upon the accessed portion of the managed logistics information. Such notification event is related to status information associated with the container or an item stored within the container.

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

Abstract: Methods, apparatus, and systems are described for managing logistics information related to a container using a container interface display apparatus. The container interface display apparatus may comprise a mountable housing, a display screen, a memory, a scanner, and a wireless communication interface. The housing is coupled to the container to permit the scanner to identify an item being loaded for shipment within the container. The scanner identifies the item, and the apparatus records an association in memory as part of managed logistics information that reflects an established and tracked relationship between the container and the item. The apparatus increments package count information (another part of the managed logistics information) to reflect that the item is loaded within the container. The apparatus generates electronic logistics monitor information on the display screen to include at least a portion of the managed logistics information related to the container.

Abstract: A novel process is provided for the efficient preparation of an asymmetric compound of structural formula I: comprising a copper-catalyzed, carbon-nitrogen cross-coupling step. The process described as part of the present invention can be used to manufacture poly (ADP-ribose) polymerase (PARP) inhibitors, which may be useful for the treatment of cancer. In particular, the present invention describes a process for the manufacture of the PARP inhibitor, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide.

Abstract: In an example, there is disclosed a computing apparatus, having a computing resource; a bespoke sensor for measuring at least one parameter of usage of the computing resource; and one or more logic elements providing a trusted compute meter (TCM) agent to: receive an external workload; provision a workload enclave; execute the external workload within the TCM enclave; and measure resource usage of the external workload via the bespoke sensor. There is also disclosed a computer-readable medium having stored thereon executable instructions for providing a TCM agent, and a method of providing a TCM agent.

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

Abstract: Particular embodiments described herein provide for modular device assemblies and methods for enabling maintenance and servicing, particularly by an unmanned aerial vehicle. A device assembly comprises a plurality of modules, each module having control circuitry, a communications port and contact points to couple the modules. When the modules are coupled, the communications ports are connected to create a bus for communications between the modules. The modular device structure where modules are removable and replaceable allows for an unmanned aerial vehicle to perform maintenance on the device.

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

Abstract: The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.

Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.

Abstract: Particular embodiments described herein provide for modular device assemblies and methods for enabling maintenance and servicing, particularly by an unmanned aerial vehicle. A device assembly comprises a plurality of modules, each module having control circuitry, a communications port and contact points to couple the modules. When the modules are coupled, the communications ports are connected to create a bus for communications between the modules. The modular device structure where modules are removable and replaceable allows for an unmanned aerial vehicle to perform maintenance on the device.

Abstract: A novel process is provided for the efficient preparation of an asymmetric compound of structural formula I: comprising a copper-catalyzed, carbon-nitrogen cross-coupling step. The process described as part of the present invention can be used to manufacture poly (ADP-ribose) polymerase (PARP) inhibitors, which may be useful for the treatment of cancer. In particular, the present invention describes a process for the manufacture of the PARP inhibitor, 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide.

Abstract: The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: which exhibits Acetyl-CoA carboxylase (“ACC”) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

Abstract: The present invention provides solid forms of compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, methods of producing the same, and methods of using the same in the treatment of ACC-mediated diseases.