Abstract: An inserter assembly (200) for deploying an intravesical device into a urinary bladder of a patient includes a placement catheter (210), a receiving funnel (220), and a stylet (230). The placement catheter defines a lumen extending from a proximal catheter end to an exit opening. The receiving funnel is secured to the placement catheter. The stylet is removably received through the receiving funnel within the lumen. The stylet includes a stylet body and a paddle (238). The stylet body is dimensioned to drive the intravesical device through the lumen and the exit opening into the bladder. The paddle is fixed to the stylet body about the proximal stylet end and is engageable with the receiving funnel. The paddle optionally includes a fitting (242) being lockably engageable with the receiving funnel to removably secure the stylet to the placement catheter.

Abstract: The present invention relates to antibody-drug conjugates comprising (i) an antibody or antigen-binding fragment thereof, (ii) a polymer comprising a particular repeat unit comprising an amino acid derivative, which is covalently bound to one or more biologically active moieties, such as small molecule drugs, optionally via a linker, and (iii) a polymer-antibody linker moiety which is covalently bound to both the polymer and the antibody or antigen-binding fragment thereof. Additionally, the present invention relates to pharmaceutical compositions comprising the antibody-drug conjugates and to use of the antibody-drug conjugates in medicine.

Abstract: An adjustable weight plate to be used with a standard or Olympic barbell handle, comprising a wide opening that is easy to fill with sand or other loose filler material, multiple inner compartments to separate out the sand and equalize the weight, and reinforcing dividers to strengthen the weight plate. The adjustable weight plate also comprises a metal collar to strengthen the inner radius of the weight plate, and an easy-fill funnel to fill the weight plate with sand.

Abstract: A blending system includes a blender base and a container. The blender base includes a housing that houses a motor. The container is attachable to the blender base. The blending system includes a user device that communicates with the blender base. The user device may communicate with a remote computing device. The user device generates instructions and recipes for the blender base.

Abstract: An adjustable weight plate to be used with a standard or Olympic barbell handle, comprising a wide opening that is easy to fill with sand or other loose filler material, multiple inner compartments to separate out the sand and equalize the weight, and reinforcing dividers to strengthen the weight plate. The adjustable weight plate also comprises a metal collar to strengthen the inner radius of the weight plate, and an easy-fill funnel to fill the weight plate with sand.

Abstract: Techniques are described for collecting descriptions of an entity from different data sources and using a numeric comparison and textual centrality measure to automatically select a best description. In one implementation, a method includes: retrieving a real property description dataset, the real property description dataset including descriptions from multiple data sources that describe the real property; extracting, from each of the descriptions, numbers that identify the property; performing a numerical comparison of the numbers extracted from each of the descriptions to determine if any descriptions needs to be discarded from further consideration; applying a text cleaning process to normalize the descriptions; and performing a textual centrality measure of remaining descriptions to determine a level agreement of each of the remaining descriptions with each of the other remaining descriptions; and using at least the textual centrality measure to select a description.

Abstract: A blending system includes a blender base and a container. The blender base includes a housing that houses a motor. The container is attachable to the blender base. The blending system includes a user device that communicates with the blender base. The user device may communicate with a remote computing device. The user device generates instructions and recipes for the blender base.

Abstract: A blending system includes a blender base and a container. The blender base includes a housing that houses a motor. The container is attachable to the blender base. The blending system includes a user device that communicates with the blender base. The user device may communicate with a remote computing device. The user device generates instructions and recipes for the blender base.

Abstract: The present invention provides, among other things, improved therapeutic compositions comprising a C3 fusion protein and methods of making and using the same. In particular, the present invention provides improved methods for the treatment of spinal cord injury and other CNS trauma and/or facilitate axon growth or other tissue repair.

Abstract: The present invention provides, among other things, improved therapeutic compositions comprising a C3 fusion protein and methods of making and using the same. In particular, the present invention provides improved methods for the treatment of spinal cord injury and other CNS trauma and/or facilitate axon growth or other tissue repair.

Abstract: A blending system includes a container or housing, a blade assembly, and an insert are described herein. The insert is disposed in or on the container or housing. The blade assembly includes a drive shaft. The drive shaft is rotatable. A magnet is attached to the drive shaft. Rotation of the magnet induces current in the insert. The current induces heat.

Abstract: The present invention provides, among other things, improved therapeutic compositions comprising a C3 fusion protein and methods of making and using the same. In particular, the present invention provides improved methods for the treatment of spinal cord injury and other CNS trauma and/or facilitate axon growth or other tissue repair.

Abstract: Techniques are described for collecting descriptions of an entity from different data sources and using a numeric comparison and textual centrality measure to automatically select a best description. In one implementation, a method includes: retrieving a real property description dataset, the real property description dataset including descriptions from multiple data sources that describe the real property; extracting, from each of the descriptions, numbers that identify the property; performing a numerical comparison of the numbers extracted from each of the descriptions to determine if any descriptions needs to be discarded from further consideration; applying a text cleaning process to normalize the descriptions; and performing a textual centrality measure of remaining descriptions to determine a level agreement of each of the remaining descriptions with each of the other remaining descriptions; and using at least the textual centrality measure to select a description.

Abstract: An automated medical apparatus for providing medical care in remote areas to a patient is provided. The apparatus includes a container having corrugated steel enclosure on all sides and transportable using a standardized commercial shipping mechanism, the container having a door with a handle and lock mechanism for secure entry and secure accommodation of the patient for treatment. The container has integrated into an inner ceiling side of the container, a plurality of automated dispensers, the dispensers configured for dispensing sterilization material upon determining by the apparatus that the door has been opened and closed, a first time and a second time respectively, such that the patient is assumed to have completed the treatment and exited the container. Further, the apparatus includes a power management device, a processor, a medical device interface, and a patient interface.

Abstract: The invention provides a dressing system for a wound comprising an absorbent pad; at least one sensor for detecting wound or dressing data, wherein the at least one sensor is a moisture sensor; a flexible electronic circuit communicable with the sensor; a backing film adapted to cooperate with the absorbent pad, wherein the electronic circuit and the at least one sensor is printed directly on the backing film; and a communications module adapted to communicate the wound data from the electronic circuit to a user or clinician. The invention provides a simple to use disposable dressing wound system that is effective in providing dressing wound data that provides an indicator of the status of the wound as well as information that the dressing wound system needs to be replaced.

Abstract: Methods and systems are provided for adjusting vehicle grille shutters based on a direction of motion of the grille shutters. In one example, a method includes adjusting a motor coupled to the grille shutters based on the direction of motion of the grille shutters, a desired opening of the grille shutters, and vehicle speed. Further, the method may include determining the direction of motion of the grille shutters based on a desired motor position relative to an actual motor position.

Abstract: An automated grill cleaning system for automatically cleaning a grill in a cooker includes a cooking unit that may be used to cook. The cooking unit has a housing and a grill is positioned in the housing. The housing has an outer wall. A cleaning unit is coupled to the cooking unit and the cleaning unit is positioned on the outer wall. The cleaning unit selectively engages the grill. The cleaning unit urges itself to travel along the grill to abrade debris from the grill.

Abstract: A blending system includes a blender base and a container. The blender base includes a housing that houses a motor. The container is attachable to the blender base. The blending system includes a user device that communicates with the blender base. The user device may communicate with a remote computing device. The user device generates instructions and recipes for the blender base.

Abstract: An automated medical apparatus for providing medical care in remote areas to a patient is provided. The apparatus includes a container having corrugated steel enclosure on all sides and transportable using a standardized commercial shipping mechanism, the container having a door with a handle and lock mechanism for secure entry and secure accommodation of the patient for treatment. The container has integrated into an inner ceiling side of the container, a plurality of automated dispensers, the dispensers configured for dispensing sterilization material upon determining by the apparatus that the door has been opened and closed, a first time and a second time respectively, such that the patient is assumed to have completed the treatment and exited the container. Further, the apparatus includes a power management device, a processor, a medical device interface, and a patient interface.