Abstract: A yoga mat comprising a folding hinge, said yoga mat designed to be folded in the middle and then rolled up in such a way that the edges of the mat line up when it is folded and then rolled.

Abstract: Methods and systems are provided for adjusting vehicle grille shutters based on a direction of motion of the grille shutters. In one example, a method includes adjusting a motor coupled to the grille shutters based on the direction of motion of the grille shutters, a desired opening of the grille shutters, and vehicle speed. Further, the method may include determining the direction of motion of the grille shutters based on a desired motor position relative to an actual motor position.

Abstract: A time reference system for generating a time reference from signals produced by a global navigation satellite constellation has a satellite signal receiver to receive and down-convert code-modulated signals from a plurality of satellites and a correlator to track and decode the down-converted signals to provide signals containing partial pseudo-range measurements for respective satellites. A data processing arrangement receives assistance data from an external source and performs data-bit synchronization in which bit edges of a low frequency data bit stream carried by the received satellite signals are identified, to perform a preliminary position-velocity-time solution to provide an approximate time reference, and to perform auto-correlation of pre-selected data sequences in the data stream to resolve time ambiguities thereby to compute a precise time reference signal in weak received signal conditions.

Abstract: A time reference system for generating a time reference from signals produced by a global navigation satellite constellation has a satellite signal receiver to receive and down-convert code-modulated signals from a plurality of satellites and a correlator to track and decode the down-converted signals to provide signals containing partial pseudo-range measurements for respective satellites. A data processing arrangement receives assistance data from an external source and performs data-bit synchronisation in which bit edges of a low frequency data bit stream carried by the received satellite signals are identified, to perform a preliminary position-velocity-time solution to provide an approximate time reference, and to perform auto-correlation of pre-selected data sequences in the data stream to resolve time ambiguities thereby to compute a precise time reference signal in weak received signal conditions.

Abstract: Compositions comprising at least one C4-C30 olefin or oxidation product thereof and kerosene or an aromatic solvent are particularly effective for use in removing asphaltene and asphaltene-containing organic deposits and in preventing or reducing the precipitation and deposition of asphaltenes from hydrocarbon fluids. When added to heavy oils comprising asphaltenes, alone or in combination with dispersants and further inhibitors, the invented compositions lower viscosity and pour point, and aid in preventing asphaltene precipitation during transport and in combustion.

Abstract: A refrigerator or a freezer comprises a primary refrigeration system (11) which is augmented with a passive secondary refrigeration loop (15) having a condenser (30) in thermal contact with a primary fluid line (12) at the location between a primary compressor (16) and a primary condenser (18) and preferably placed outside a building so that the passive secondary refrigeration loop (15) provides cooling to the primary refrigeration system (11) when the outside temperature is sufficiently low The condenser (30) of the passive secondary refrigeration loop (15) is positioned above the points where the primary fluid line (12) connects with mlet (32) and outlet (34) lines of the secondary loop condenser (30)

Abstract: The present invention relates to human Rho-kinase I (ROCK I), ROCK I binding pockets, ROCK I-like binding pockets. More particularly, the present invention provides a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen for and design compounds, including inhibitory compounds, that bind to ROCK I protein or ROCK I protein homologues, or complexes thereof. The invention also relates to crystallizable compositions and crystals comprising ROCK I kinase domain and ROCK I kinase domain complexed with an inhibitor of that domain. The invention also relates to methods of identifying inhibitors of the ROCK I kinase domain.

Abstract: The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological or histological analysis to contrast the nuclear portion of the cell from the cytoplasmic portion, and systems and methods for illuminating a cytological sample. The analysis can be automated or manual.

Abstract: The present invention relates to human Rho-kinase I (ROCK I), ROCK I binding pockets, ROCK I-like binding pockets. More particularly, the present invention provides a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen for and design compounds, including inhibitory compounds, that bind to ROCK I protein or ROCK I protein homologues, or complexes thereof. The invention also relates to crystallizable compositions and crystals comprising ROCK I kinase domain and ROCK I kinase domain complexed with an inhibitor of that domain. The invention also relates to methods of identifying inhibitors of the ROCK I kinase domain.

Abstract: The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological or histological analysis to contrast the nuclear portion of the cell from the cytoplasmic portion, and systems and methods for illuminating a cytological sample. The analysis can be automated or manual.

Abstract: The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological or histological analysis to contrast the nuclear portion of the cell from the cytoplasmic portion, and systems and methods for illuminating a cytological sample. The analysis can be automated or manual.

Abstract: Compositions comprising at least one C4-C30 olefin or oxidation product thereof and kerosene or an aromatic solvent are particularly effective for use in removing asphaltene and asphaltene-containing organic deposits and in preventing or reducing the precipitation and deposition of asphaltenes from hydrocarbon fluids. When added to heavy oils comprising asphaltenes, alone or in combination with dispersants and further inhibitors, the invented compositions lower viscosity and pour point, and aid in preventing asphaltene precipitation during transport and in combustion.

Abstract: A system and method of accurately predicting and reporting a value of a property based on a weighted average of values predicted by at least two prediction models. The system and method include the steps of accessing predicted values, determined by the prediction models, for the property; determining property-specific proportional prediction error distribution information for each predicted value determined by each prediction model; assigning a weight to the predicted value determined by each prediction model by using the property-specific proportional prediction error distribution information; and generating a property-specific weighted average value based on combination of the weight and the predicted value determined by each prediction model and reporting the property-specific weighted average value to minimize prediction error during prediction of the property value.

Abstract: The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site binding pockets of IMPDH. Such data storage material is capable of displaying such molecules and molecular complexes, or their structural homologues, as a graphical three-dimensional representation on a computer screen. This invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. In addition, this invention relates to methods of using the structure coordinates to screen and design compounds, including inhibitory compounds, that bind to IMPDH or homologues thereof. This invention also relates to molecules and molecular complexes which comprise the active site binding pockets of IMPDH or close structural homologues of the active site binding pockets. This invention also relates to compounds and pharmaceutical compositions which are inhibitors of IMPDH.

Abstract: The present invention relates to crystallized molecules and molecular complexes which comprise the active site binding pocket or the FKBP12/FK506 binding pocket of calcineurin or close structural homologues to either binding pocket. This invention also relates to a data storage material encoded with the corresponding structure coordinates of those crystallized molecules or molecular complexes. Such data storage material is capable of displaying such molecules and molecular complexes as a graphical three-dimensional representation on a computer screen. In addition, this invention relates to methods of using the structure coordinates of those molecules or molecular complexes to solve the structure of homologous proteins. This invention also relates to methods of using the structure coordinates to screen and design compounds that bind to calcineurin or homologues thereof.

Abstract: A system and method of accurately predicting and reporting a value of a property based on a weighted average of values predicted by at least two prediction models. The system and method include the steps of accessing predicted values, determined by the prediction models, for the property; determining property-specific proportional prediction error distribution information for each predicted value determined by each prediction model; assigning a weight to the predicted value determined by each prediction model by using the property-specific proportional prediction error distribution information; and generating a property-specific weighted average value based on combination of the weight and the predicted value determined by each prediction model and reporting the property-specific weighted average value to minimize prediction error during prediction of the property value.

Abstract: The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological or histological analysis to contrast the nuclear portion of the cell from the cytoplasmic portion, and systems and methods for illuminating a cytological sample. The analysis can be automated or manual.

Abstract: The present invention relates to the analysis of cytological material. Specifically, the invention relates to stains and methods of producing the stains, methods of staining cells for cytological or histological analysis to contrast the nuclear portion of the cell from the cytoplasmic portion, and systems and methods for illuminating a cytological sample. The analysis can be automated or manual.

Abstract: A filter assembly for fluids such as air and water employs a cleanable filter. The filter is located within a housing having a reservoir, and a steam generator which can be selectively operated to clean the filter.