Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.

Abstract: A compounding pharmacy includes at least one clean room for manually mixing pharmaceutical ingredients to form a specialized product. The at least one clean room has a heating, ventilation, and air conditioning with fluid paths that extend from at least one air intake to an exhaust within the at least one clean room. Each of the at least two fluid paths has at least two air dampers that can be selectively opened to allow flow through the respective fluid path or closed to prevent flow through the respective fluid path. Each of the at least two fluid paths include at least one evaporator coil. The at least one evaporator coil includes at least one tube for conveying a cooling fluid and a plurality of fins. The at least one tube and the plurality of fins of the at least one evaporator coil are made of aluminum or an aluminum alloy.

Abstract: A conveyor belt scraper assembly is provided. The conveyor belt scraper assembly includes one or more scrapers supported by a support. The assembly includes a scraper realignment configured to move at least one of the one or more scrapers, from a first state to a second state, wherein movement of said at least one of the one or more scrapers can be in a translational direction and a rotational direction. A method of operating a conveyor belt assembly is also provided.

Abstract: Embodiments include a microphone array comprising a first plurality of directional microphone elements arranged in a first cluster formed by directing a front face of the microphone elements towards a center of the first cluster, and a second plurality of directional microphone elements arranged in a second cluster formed by directing a front face of the elements away from a center of the second cluster, wherein the first cluster is disposed vertically above the second cluster. Also provided is a microphone comprising a first microphone array comprising a plurality of directional microphone elements arranged in close proximity to each other and configured to capture near-field sounds within a first range of frequencies, and a second microphone array disposed concentrically around the first microphone array, the second array comprising a plurality of omnidirectional microphone elements configured to capture near-field sounds within a second range of frequencies higher than the first range.

Abstract: Provided are adoptive cell therapy methods involving the administration of doses of cells for treating B cell malignancies. The cells generally express recombinant receptors such as chimeric antigen receptors (CARs). In some embodiments, the methods are for treating subjects with chronic lymphocytic leukemia (CLL). In some embodiments, the methods are for treating subjects with non-Hodgkin lymphoma (NHL). In some embodiments, the methods involve prior administration of a lymphodepleting therapy, such as prior administration of fludaribine and/or another lymphodepleting chemotherapeutic agent, for example cyclophosphamide. In some embodiments, features of the methods include an increase in complete remission, overall survival and/or progression free survival of subjects treated in accord with the provided methods.

Abstract: Provided herein are methods, compositions and articles of manufacture for use in connection with cell therapy involving the administration of one or more doses of a therapeutic T cell composition. The cells of the T cell composition express recombinant receptors such as chimeric receptors, e.g. chimeric antigen receptors (CARs) or other transgenic receptors such as T cell receptors (TCRs). Features of the provided embodiments, including the numbers of cells or units of cells administered and/or the potency of administered cells, provide various advantages, such as lower risk of toxicity in subjects administered the T cell compositions.

Abstract: Systems and methods described herein provide for novel configuration features for setting up a user device automatically to connect to a network and register the user device to a user account. A mapping of user devices to cryptographic keys for the user devices may be maintained by a computer system. The computer system may receive information that specifies network information and user account information for a particular user device. A mapping of the network information and user account information to the particular user device may be generated. A machine-readable code that includes the network information for connecting the particular user device to the network and a token that includes credentials for the user account information may be generated and transmitted to a assistant configuration device.

Abstract: A wireless audio system configured to perform an acoustic ranging operation is disclosed. The audio system comprises an audio transmitter, and audio receiver, and is configured to determine a distance between the audio transmitter and the audio receiver.

Abstract: Embodiments include a microphone array comprising a first plurality of directional microphone elements arranged in a first cluster formed by directing a front face of the microphone elements towards a center of the first cluster, and a second plurality of directional microphone elements arranged in a second cluster formed by directing a front face of the elements away from a center of the second cluster, wherein the first cluster is disposed vertically above the second cluster. Also provided is a microphone comprising a first microphone array comprising a plurality of directional microphone elements arranged in close proximity to each other and configured to capture near-field sounds within a first range of frequencies, and a second microphone array disposed concentrically around the first microphone array, the second array comprising a plurality of omnidirectional microphone elements configured to capture near-field sounds within a second range of frequencies higher than the first range.

Abstract: Embodiments include a microphone array comprising a first plurality of directional microphone elements arranged in a first cluster formed by directing a front face of said microphone elements towards a center of the first cluster, and a second plurality of directional microphone elements arranged in a second cluster formed by directing a front face of said elements away from a center of the second cluster, wherein the first cluster is disposed vertically above the second cluster. Also provided is a microphone comprising a first microphone array comprising a plurality of directional microphone elements arranged in close proximity to each other and configured to capture near-field sounds within a first range of frequencies, and a second microphone array disposed concentrically around the first microphone array, the second array comprising a plurality of omnidirectional microphone elements configured to capture near-field sounds within a second range of frequencies higher than the first range.

Abstract: A conveyor belt scraper comprising a body having a proximal mounting base and a distal scraping tip, the mounting base includes a first engagement formation configured to engage with a second engagement formation located on a shaft assembly, wherein the first engagement formation and the second engagement formation are corresponding male and female members which are engaged or disengaged by rotation of the scraper relative to the shaft assembly about a longitudinal axis of the shaft assembly.

Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.

Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.

Abstract: Embodiments include an array microphone comprising a plurality of microphone sets arranged in a linear pattern relative to a first axis and configured to cover a plurality of frequency bands. Each microphone set comprises a first microphone arranged along the first axis and a second microphone arranged along a second axis orthogonal to the first microphone, wherein a distance between adjacent microphones along the first axis is selected from a first group consisting of whole number multiples of a first value, and within each element, a distance between the first and second microphones along the second axis is selected from a second group consisting of whole number multiples of a second value.

Abstract: The present technology can provide a mechanism for providing a team member transfer interface to an administrator user for transferring team member user accounts from one team to another and also a mechanism for transferring the team member user accounts, such as by switching an assignment of one or more user accounts from a first team to another in a single atomic action. The transferring of the team member user accounts may also depend on passing a set of validation checks that check for inconsistencies that could cause an error in the transfer, and also updating access and privileges associated with being members of certain teams.

Abstract: Offset cartridge microphones are provided that include multiple unidirectional microphone cartridges mounted in an offset geometry. Various desired polar patterns and/or desired steering angles can be formed by processing the audio signals from the multiple cartridges, including a toroidal polar pattern. The offset geometry of the cartridges may include mounting the cartridges so that they are immediately adjacent to one another and so that their center axes are offset from one another. The microphones may have a more consistent on-axis frequency response and may more uniformly form desired polar patterns and/or desired steering angles by reducing the interference and reflections within and between the cartridges.

Abstract: The present technology can provide a mechanism for providing a team member transfer interface to an administrator user for transferring team member user accounts from one team to another and also a mechanism for transferring the team member user accounts, such as by switching an assignment of one or more user accounts from a first team to another in a single atomic action. The transferring of the team member user accounts may also depend on passing a set of validation checks that check for inconsistencies that could cause an error in the transfer, and also updating access and privileges associated with being members of certain teams.

Abstract: Embodiments include an array microphone comprising a plurality of microphone sets arranged in a linear pattern relative to a first axis and configured to cover a plurality of frequency bands. Each microphone set comprises a first microphone arranged along the first axis and a second microphone arranged along a second axis orthogonal to the first microphone, wherein a distance between adjacent microphones along the first axis is selected from a first group consisting of whole number multiples of a first value, and within each element, a distance between the first and second microphones along the second axis is selected from a second group consisting of whole number multiples of a second value.

Abstract: The present technology can provide a mechanism for providing a team member transfer interface to an administrator user for transferring team member user accounts from one team to another and also a mechanism for transferring the team member user accounts, such as by switching an assignment of one or more user accounts from a first team to another in a single atomic action. The transferring of the team member user accounts may also depend on passing a set of validation checks that check for inconsistencies that could cause an error in the transfer, and also updating access and privileges associated with being members of certain teams.

Abstract: A wireless audio system configured to perform an acoustic ranging operation is disclosed. The audio system comprises an audio transmitter, and audio receiver, and is configured to determine a distance between the audio transmitter and the audio receiver.