Abstract: The present invention is directed to a stable solid formulations of tetrahydrobiopterin, processes for producing them, and treatment methods using such formulations.

Abstract: An exemplary embodiment of the invention relates to a method and storage medium for integrating forecasting and replenishment activities for a networked supply chain including an enterprise and at least one supplier. The method comprises receiving a demand forecast for a first manufacturing cycle from the enterprise, performing a hub inventory assessment, performing a capability assessment, and transmitting a commitment response to the enterprise based upon the demand forecast, the results of the hub inventory assessment, and the results of the capability assessment. The demand forecast is utilized to manage hub inventory for use in a second manufacturing cycle. Other embodiments include a storage medium for implementing the invention.

Abstract: Disclosed herein is an integrated method and system for managing human resources. Specifically, the method and system integrates several processes (e.g., a process for developing a strategy and particularly for developing a set of rules on how human resources will be managed and sourced, a process for developing a long-term strategic plan for sourcing human resources to satisfy demands, a process for developing a near-term operational plan recommending individual human resources be used to satisfy selected demands, a process for selecting and assigning individual resources to specific engagements, etc.). Thus, the method operates through a spectrum of time horizons from the strategic to real time, providing a coherent and cohesive system for matching supply to demand based on the priorities of the business as represented through the set of rules.

Abstract: Disclosed herein is an integrated method and system for managing human resources. Specifically, the method and system integrates several processes (e.g., a process for developing a strategy and particularly for developing a set of rules on how human resources will be managed and sourced, a process for developing a long-term strategic plan for sourcing human resources to satisfy demands, a process for developing a near-term operational plan recommending individual human resources be used to satisfy selected demands, a process for selecting and assigning individual resources to specific engagements, etc.). Thus, the method operates through a spectrum of time horizons from the strategic to real time, providing a coherent and cohesive system for matching supply to demand based on the priorities of the business as represented through the set of rules.

Abstract: An exemplary embodiment of the invention relates to a method, system, and storage medium for resolving demand and supply imbalances. The method comprises identifying at least one excess component inventory liability or constraint in supply capability for an end product by matching current buying patterns for the end product against inventory liability and supply capability based on a previous demand forecast. Where excess component inventory liability exists the method refocuses the excess component inventory liability by determining alternative end products that use components identified in the excess component inventory liability; and executes sales activities for enticing sales of the alternative end products. Where constrained supply capability exists, the method determines alternative end products that are functionally equivalent to those identified in the constrained supply capability; and executes sales activities for enticing sales of functionally equivalent alternative end products.

Abstract: Inductively coupled plasma (ICP) reforming converts carbonaceous compounds into a fuel for use in generating electrical power. Energy rich hydrocarbon fuels, such as coal, marine diesel, oils, and hydrocarbon wastes are employed as a feedstock for the ICP, which transforms the feedstock into a fuel that can be used by fuel cells and gas turbines for the production of electricity. The overall efficiency of an ICP-based electrical power system can be increased by providing partial oxidation within the reaction vessel. The partial oxidation conditions consume a small amount of the reformed fuel gas, thereby liberating sufficient thermal energy to reduce the electrical power requirements of the ICP to maintain desired reactor temperatures, and providing an increase in the overall net electrical power production. The integrated power production system can also adjust to meet an increased requirement for process heat and steam by balancing the effect of partial oxidation.

Abstract: Torsion control devices for use in an article of footwear are disclosed. An article of footwear comprises: a sole having a forefoot portion and a rearfoot portion; and a torsion element disposed in the sole, wherein the torsion element allows the forefoot portion to rotate in a first direction relative to the rearfoot portion and restricts rotation of the forefoot portion relative to the rearfoot portion in a second direction.

Abstract: A grip & roll in place string (G.R.i.P.-String) technique is described for the purpose of fastening or securing items that require additional physical support. The inventive device includes standard nylon string material with an integrated hook & loop section for increased gripping after the string has been tied. The string material is 100% multifilament nylon (FIG. 1, item 15). It is available in colors and resistant to chemicals and abrasion and is non-spliceable. The ‘Hook & Loop’ sections are integrated into the nylon string material. They consist of alternating minute hooks and loop pile that are integrated in a 45 degree angle (FIG. 2, item 30) to the string 0 degree line (FIG. 2, item 25) detail) from end-to-end of the ‘Hook & Loop’ section. The tie-through eye (FIG. 1, item 10) is a means to attach the G.R.i.P.-String fastener to the object that requires additional physical fastening support.

Abstract: High-power inductively coupled plasma technology is used for thermal cracking and vaporization of continuously fed carbonaceous materials into elemental carbon, for reaction with separate and continuously fed metal catalysts inside a gas-phase high-temperature reactor system operating at or slightly below atmospheric pressures. In one particularly preferred embodiment, in-flight growth of carbon nanomaterials is initiated, continued, and controlled at high flow rates, enabling continuous collection and product removal via gas/solid filtration and separation methods, and/or liquid spray filtration and solid collection methods suitable for producing industrial-scale production quantities. In another embodiment, the reaction chamber and/or filtration/separation media include non-catalytic or catalytic metals to simultaneously or separately induce on-substrate synthesis and growth of carbon nanomaterials.

Abstract: High-power inductively coupled plasma technology is used for thermal cracking and vaporization of continuously fed carbonaceous materials into elemental carbon, for reaction with separate and continuously fed metal catalysts inside a gas-phase high-temperature reactor system operating at or slightly below atmospheric pressures. In one particularly preferred embodiment, in-flight growth of carbon nanomaterials is initiated, continued, and controlled at high flow rates, enabling continuous collection and product removal via gas/solid filtration and separation methods, and/or liquid spray filtration and solid collection methods suitable for producing industrial-scale production quantities. In another embodiment, the reaction chamber and/or filtration/separation media include non-catalytic or catalytic metals to simultaneously or separately induce on-substrate synthesis and growth of carbon nanomaterials.

Abstract: A system for resolving demand and supply imbalances includes a supply liability reduction process (SLRP) executable upon identifying an excess component inventory liability. The SLRP includes: a procurement and development assessment sub-process that represents a greatest magnitude of liability; a liability council assessment sub-process that represents a magnitude of liability less than that of the procurement and development assessment sub-process; a sales activities sub-process that represents a magnitude of liability less than that of the liability council assessment sub-process; and a liability write-off sub-process that represents a magnitude of liability less than that of the sales activities sub-process. The SLRP performs one or more sub-processes in an order of the magnitude of liability.

Abstract: A storage medium for resolving demand and supply imbalances is provided. The storage medium includes machine-readable computer program code and instructions for causing a computer to implement a method. The method includes identifying an excess component inventory liability or constraint in supply capability for an end product by matching current buying patterns for the end product against inventory liability and supply capability based on a previous demand forecast. Where excess component inventory liability exists, the method includes: refocusing the excess component inventory liability by determining alternative end products that use components identified in the excess component inventory liability; and executing sales activities for enticing sales of the alternative end products.

Abstract: The present disclosure provides a method that efficiently produces (6R)-tetrahydrobiopterin in high yield and purity. The method includes the step of hydrolyzing diacetylbiopterin to biopterin under basic conditions in a biphasic mixture comprising an organic phase and an aqueous phase. After substantially complete hydrolysis of diacetylbiopterin, the aqueous phase containing biopterin can be separated from the organic phase containing most of the organic impurities, which avoids the time-consuming step of isolating biopterin as a solid. The aqueous solution containing biopterin is stereoselectively hydrogenated to (6R)-tetrahydrobiopterin under basic conditions and high hydrogen pressure in the presence of a metal catalyst (e.g., a platinum catalyst). To improve the purification of an acid addition salt of (6R)-tetrahydrobiopterin (e.g., (6R)-tetrahydrobiopterin dihydrochloride), any residual salts (e.g.

Abstract: The present invention is directed to a stable solid formulations of tetrahydrobiopterin, processes for producing them, and treatment methods using such formulations.

Abstract: A tile having a front face for displaying and an underside for securing to a tile support surface, the underside having a closed path seal wall extending backwards. The seal wall is configured to provide a seal between the tile and a tile support surface to prevent substance ingress interior of the closed path of the seal wall. A tile having a seal wall also configured to provide a seal between the tile and a second like tile. A tile having an underside that presents a tile coupling configured to communicate with a tile support coupling to provide a first releasable coupling arrangement. A tile support board having a rear face for securing to a support surface and a front face providing a tile support surface and presenting a tile support coupling, such that the tile may be releasably coupled to the tile support board.

Abstract: High-power inductively coupled plasma technology is used for thermal cracking and vaporization of continuously fed carbonaceous materials into elemental carbon, for reaction with separate and continuously fed metal catalysts inside a gas-phase high-temperature reactor system operating at or slightly below atmospheric pressures. In one particularly preferred embodiment, in-flight growth of carbon nanomaterials is initiated, continued, and controlled at high flow rates, enabling continuous collection and product removal via gas/solid filtration and separation methods, and/or liquid spray filtration and solid collection methods suitable for producing industrial-scale production quantities. In another embodiment, the reaction chamber and/or filtration/separation media include non-catalytic or catalytic metals to simultaneously or separately induce on-substrate synthesis and growth of carbon nanomaterials.

Abstract: Integrated opto-electronic oscillators that use micro resonators in the optical section of the opto-electronic feedback loop.

Abstract: The present invention is directed to a stable solid formulations of tetrahydrobiopterin, processes for producing them, and treatment methods using such formulations.

Abstract: Devices and techniques for filtering RF or microwave frequencies by optical filtering using a tunable optical filter.

Abstract: A method, data processing system, and computer usable program code are provided for optimizing a workforce for a company. An organizational development structure and an optimization performance structure are identified. A set of functional strategy tasks are developed using the organizational development structure and the optimization performance structure. An inventory of current tasks and skills within the company is performed, and tasks and skills from the current inventory of tasks and skills that are associated with the set of functional strategy tasks are identified to form a set of identified tasks and skills. A set of skill gaps are then identified using the set of identified tasks and skills.