Abstract: The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.

Abstract: The invention relates to a seal for a sawing machine (1) for separating electronic components (12), comprising: an elongate form-retaining holder (20,22), a flexible, elongate expandable body (8,9)and a pressure source (24) for a medium, wherein the elongate expandable body (8,9) is provided with a strengthened elongate edge (21) which lies clear of the form-retaining holder (20,22) The invention also relates to a sawing machine (1) for separating electronic components (12) provided with such a seal.

Abstract: The present invention relates to a method of processing a solder masked carrier with electronic components, comprising the detection of a carrier related reference and the detection of a solder mask dependent reference, which detected reference are used for processing the position of the solder mask on the carrier. The invention also relates to an electronic component as produced with such method.

Abstract: The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycystic ovarian syndrome, cancer, and inflammatory disorders—using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.

Abstract: In accordance with an example embodiment, a transmission shifting apparatus may include a transmission having a plurality of gears and a clutch positioned between a power source and the transmission. A shift lever may operably connect to the transmission, such that movement of the shift lever causes the transmission to shift gears. A shift sensor may detect when the shift lever receives an operator input in a manner to generate a gear shift. A shift controller may selectively disengage the clutch when the shift sensor detects the operator input applied to the shift lever, and selectively engage the clutch when the shift controller determines the shift is complete.

Abstract: The invention provides, inter alia, methods of monitoring the fructose response of a subject by determining the level of fibroblast growth factor 21 (FGF21) gene expression product in a biological sample (such as a serum sample) from the subject, where the subject was previously administered a fructose bolus. The invention also provides methods of monitoring the response of a subject to a treatment for a disorder of metabolism, for discriminating fructose intolerance from other gastrointestinal disorders not associated with fructose intolerance, for identifying a subject at risk for developing a disorder of metabolism, as well as methods of treatment for a disorder of metabolism.

Abstract: The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.

Abstract: The invention provides diagnostic and prognostic methods and methods of evaluating treatment protocols for disorders such as obesity, diabetes, metabolic syndrome, cancer and vascular disease by detecting the levels of a novel isoform of ChREBP, termed ChREBP ?. The invention also provides nucleic acids, proteins, reporter constructs based on ChREBP ? and methods of identifying one or more agents that modulate the expression of a ChREBP ? target gene.

Abstract: The present invention relates to an illumination system for use in a stereolithography apparatus. The illumination system includes a plurality of light-emitting diodes (LEDs), each LED having at least a first light-emitting surface and a second surface, at least one of the first and the second surface being substantially flat. The illumination further includes a plurality of electrical pathways, selectively connected to the respective LEDs, such that each LED can be individually controlled and a leveling surface. The leveling surface is substantially flat and in leveling contact with the at least one substantially flat surface of each LED, such that a two-dimensional array of LEDs extends in a plane parallel to the leveling surface.

Abstract: A system and method of layerwise production of a tangible object (5), they system comprising a construction shape (6) to form a liquid layer to be brought in contact with the tangible object; solidifying means (9) for solidifying a predetermined area of a layer (10) of the liquid (3), so as to obtain a solid layer (14) of the tangible object (5), the solid layer thus having a predetermined shape, separating means (18; 19?; 19?) for separating said solid layer from said construction shape; moving means (18) for moving, relative to one another, the construction shape (6) to a predetermined position relative to the tangible object (5), for carrying out a successive such method cycle for solidifying a predetermined area of a successive such liquid layer; the system is arranged to provide a limited volume of liquid adhered to the construction shape to form a liquid layer of limited height that does not contact the tangible object; wherein said moving of said construction shape and said solidifying of said predeter

Abstract: The invention concerns an illumination system for use in a stereolithography apparatus, comprising: a planar support; a multilens projector array mechanically supported on the planar support over the array on a plano side, and having a work surface arranged to receive a resin applying device for applying a resin layer, the projector array comprising a stack of optical elements, including a plurality of lenslets adapted to project the LEDs onto the work surface, and a two-dimensional array of individually controllable light-emitting diodes (LEDs) arranged between the planar support and the multilens projector. According to an aspect, the planar support and the plano side are supported on contact zones arranged over substantially the entire plano side; the illumination system thus forming a rigid body.

Abstract: A device for separating electronic components including sawing means and positioning means, wherein between the positioning means and the sawing means at least one transfer position is defined for the purpose of transferring positioned electronic components. A separating device for electronic components including sawing means, positioning means, inspection means, and sorting means, wherein between the positioning means and the sawing means at least one transfer position is defined for the purpose of transferring positioned electronic components between the positioning means and the sawing means, and wherein between the inspection means and the sorting means at least another transfer position is defined for the purpose of transferring the inspected separated electronic components between the inspection means and the sorting means.

Abstract: A system and method for layer-by-layer production of an object is provided. The system includes a construction shape having a carrying surface adapted for carrying a layer of build material, a plate having a holding surface adapted for holding an object in an object build area, a moveable reservoir having a plurality of containment surfaces defining a containment area adapted for containing a volume of build material within the moveable reservoir, and an exposure unit adapted for exposing at least a portion of the layer of build material in the object build area so that the portion of the layer of build material solidifies to form a solidified layer of the object.

Abstract: The present disclosure provides a gear shift assembly for shifting a transmission between a plurality of ranges. The assembly includes a user input adapted to be moved to induce a shift between two of the plurality of ranges and a shaft coupled to the user input. A movement of the user input induces a first movement of the shaft. The gear shift assembly also includes a first range member movably coupled to the shaft, where the first range member moves concomitantly with the shaft. A second range member is coupled to the shaft. The second range member also moves concomitantly with the shaft. The assembly further includes a control valve disposed in fluid communication with the second range member. The control valve is operably controlled in response to movement of the user input to direct fluid to the second range member to induce a second movement of the shaft.

Abstract: A system and method for layer-by-layer production of an object is provided. The system includes a construction shape having a carrying surface adapted for carrying a layer of build material, a plate having a holding surface adapted for holding an object in an object build area, a moveable reservoir having a plurality of containment surfaces defining a containment area adapted for containing a volume of build material within the moveable reservoir, and an exposure unit adapted for exposing at least a portion of the layer of build material in the object build area so that the portion of the layer of build material solidifies to form a solidified layer of the object.

Abstract: The invention relates to a seal for a sawing machine (1) for separating electronic components (12), comprising: an elongate form-retaining holder (20,22), a flexible, elongate expandable body (8,9)and a pressure source (24) for a medium, wherein the elongate expandable body (8,9) is provided with a strengthened elongate edge (21) which lies clear of the form-retaining holder (20,22) The invention also relates to a sawing machine (1) for separating electronic components (12) provided with such a seal.

Abstract: A system and method for layer-by-layer production of an object is provided. The system includes a construction shape having a carrying surface adapted for carrying a layer of build material, a plate having a holding surface adapted for holding an object in an object build area, a moveable reservoir having a plurality of containment surfaces defining a containment area adapted for containing a volume of build material within the moveable reservoir, and an exposure unit adapted for exposing at least a portion of the layer of build material in the object build area so that the portion of the layer of build material solidifies to form a solidified layer of the object.

Abstract: A system and method of layerwise production of a tangible object (5), they system comprising a construction shape (6) to form a liquid layer to be brought in contact with the tangible object; solidifying means (9) for solidifying a predetermined area of a layer (10) of the liquid (3), so as to obtain a solid layer (14) of the tangible object (5), the solid layer thus having a predetermined shape, separating means (18; 19?; ·?) for separating said solid layer from said construction shape; moving means (18) for moving, relative to one another, the construction shape (6) to a predetermined position relative to the tangible object (5), for carrying out a successive such method cycle for solidifying a predetermined area of a successive such liquid layer; the system is arranged to provide a limited volume of liquid adhered to the construction shape to form a liquid layer of limited height that does not contact the tangible object; wherein said moving of said construction shape and said solidifying of said predeterm

Abstract: An illumination system (30), comprising: a plurality of light-emitting diodes (LEDs) (34), each LED having at least a first, light-emitting surface (36) and a second surface (37), at least one of the first and the second surface being substantially flat; a plurality of electrical pathways (56), selectively connected to the respective LEDs, such that each LED can be individually controlled; and a levelling surface (46, 52), wherein the levelling surface is substantially flat and in levelling contact with the at least one substantially flat surface (37, 36) of each LED, such that a two-dimensional array of LEDs extends in a plane parallel to the levelling surface.

Abstract: The invention concerns an illumination system for use in a stereolithography apparatus, comprising: a planar support; a multilens projector array mechanically supported on the planar support over the array on a plano side, and having a work surface arranged to receive a resin applying device for applying a resin layer, the projector array comprising a stack of optical elements, including a plurality of lenslets adapted to project the LEDs onto the work surface, and a two-dimensional array of individually controllable light-emitting diodes (LEDs) arranged between the planar support and the multilens projector. According to an aspect, the planar support and the plano side are supported on contact zones arranged over substantially the entire plano side; the illumination system thus forming a rigid body.