Abstract: 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate, pharmaceutical compositions containing the salt and the medical use thereof, including for the treatment of schizophrenia and other psychotic disorders. Also described are methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and medical uses thereof.

Abstract: A method of performing a single step/single solvent edge bead removal (EBR) process on a photolithography layer stack including a photoresist layer and a top coat layer using propylene glycol monomethyl ether acetate (PGMEA) or a mixture of PGMEA and gamma-butyrolactone (GBL) is disclosed. The single step/single solvent EBR process is compatible with organic and inorganic BARC layers.

Abstract: A razor cartridge measurement apparatus is provided. The apparatus includes a first device for measuring a first load applied to a razor cartridge in a first direction and a second load applied to the razor cartridge in a second direction different than the first direction. The apparatus also includes a second device for measuring an angle at which the cartridge is positioned relative to a predetermined direction.

Abstract: The subject invention improves traditional safety equipment intended to protect the lower leg, ankle, foot, and toes applicable in industrial and commercial as well as casual and athletic uses. The personal protective equipment (PPE) of the subject invention comprises a soleplate, a metatarsal component, a toe cap, and a tibia-fibula component; these components can be implemented alone or in combination within a shoe or boot providing for various levels of protection depending on the desired application. Further embodiments provide for both the implementation of the protective components within the footwear as well as components that can be worn in conjunction with pre-existing shoes or boots.

Abstract: A system and method for reintegration of a redundant controller after occurrence of a fault is provided, comprising synchronizing outputs of a primary controller with outputs of secondary controllers. The controller is placed in a different mode of operation in which its output is not used in system control. A meta-controller is activated to drive the primary controller to the same states at which the secondary or redundant controllers operate. A voting mechanism is used to determine a fault in an output to a controlled device. Control of the device using the secondary outputs is effected. The primary controller recalculates the primary output, based upon the primary output; a feedback signal; and, the secondary outputs. Control using the primary output is permitted when the primary output is within an allowable range of the secondary outputs.

Abstract: Described are crystalline forms of the pharmaceutical compound “[9S-(9?,10?,12?)]-5,16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9, 12-epoxy-1H-diindolo[1,2,3-fg:3?,2?,1?-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester”, as well as methods for their use and preparation.

Abstract: The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors such as soluble TNF receptor from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) such as TNF? muteins capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as a TNF? mutein, capable of specifically binding to a targeted immune system inhibitor such as soluble TNF receptor.

Abstract: A system and related method for monitoring the state of health of sensors in an integrated vehicle stability control system. In one embodiment, the system determines whether a yaw rate sensor, a lateral acceleration sensor or a hand-wheel angle sensor has failed. The system uses a plurality of models to generate estimates of the outputs of the sensors based on the actual sensor measurements. Residuals are generated as the difference between the measured value and each of the estimates for the particular sensor. The residuals are compared to a threshold to determine whether a fault flag will be set for each residual. The threshold for the hand-wheel angle sensor is an adaptive threshold because it does not have physical redundancy. If the fault flags for the residuals for each sensor have a particular pattern, then a fault is output for that sensor.

Abstract: The system and method of the present invention is directed to emulating and configuring any of a plurality of electronic input devices. A system in accordance with one embodiment of the present invention comprises an interface and an emulator. The interface is for selecting and configuring an electronic input device from a plurality of electronic input devices, and the emulator is for emulating the electronic input device. Preferably, the plurality of electronic input devices comprise any two or more of a scroll wheel, a mouse, a joy stick, a steering wheel, an analog button, and a touch bar. Also in a preferred embodiment, the interface is an Application Programming Interface (API) and the emulator comprises a finger swipe sensor for receiving user input.

Abstract: A resilient windshield wiper assembly is disclosed which comprises a resilient wind-deflector portion molded or extruded to provide a receiving hollow for insertion of a support beam. The resilient wind-deflector portion has a feature strategically positioned and structurally effective to prevent the resilient portion from being rotated or twisted around the support beam. The wind deflector is symmetrical with respect to the axial orientation of the support beam. The symmetry allows conversion of the wind force components from lifting forces to normal forces acting to press and/or hold the wiper against the wiper surface even when subjected to side gusts or reverse head-wind forces. The symmetry further provides a strength member acting directly over the top of the wiping lip surface avoiding introducing a twisting force into the support beam.

Abstract: 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate or hydrogen malonate, pharmaceutical compositions containing these salts and the medical use thereof, including for the treatment of schizophrenia and other psychotic disorders. Also described are methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine and medical uses thereof.

Abstract: A compound 4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-2,2-dimethylpiperazine and salts thereof, pharmaceutical compositions comprising the compound and salts, and medical use thereof, including for treatment of schizophrenia and other psychotic disorders.

Abstract: A rock stabilizer includes a metal tube with a tapered distal end and a flanged proximal end capable of being positioned within a bore in a mine wall. A slit runs substantially the entire length and indentations are formed in the outer surface along the length adjacent the slit so that grout pumped into the interior of the tube flows out of the slit and into the indentations. An expander wedge within the tube adjacent the distal end is actuatable from the proximal end after the stabilizer is installed in a bore. The wedge expands the distal end of the tube to firmly anchor the stabilizer in the bore. The expander wedge is formed of one wedge welded to the interior of the tube and a second wedge moveable toward the fixed wedge. The two wedges are temporarily maintained together in the interior of the tube before actuation.

Abstract: A vehicle includes a plurality of sub-systems and corresponding controllers for effecting normal control thereover. The vehicle further includes a vehicle dynamics controller for providing high-priority sub-system commands for sub-system control to effect vehicle dynamics enhancements. The vehicle dynamics controller includes a plurality of independently decomposable and recomposable software components or layers and accessible inter-layer bus structure.

Abstract: A supervisory diagnostics system and related method for providing vehicle diagnostics for an integrated vehicle stability system that monitors the state of health of sensors, actuators, vehicle sub-system and communication sub-systems that are used in the stability control system. The diagnostics system employs an algorithm to determine whether the various sensors, actuators and sub-systems are operating properly. The algorithm determines whether the components and sub-systems are outputting valid signals at a component level. The algorithm also determines whether a bias of the sensors is below a predetermined limit. The algorithm further determines whether a comparison between the outputs of redundant sensors is below a predetermined threshold for a predetermined period of time. The system also performs a state of health analytical comparison of all the system signals. The system will go in to a fail-safe mode if a fault is detected.

Abstract: A system and method for providing state of health monitoring and fault diagnostics for a vehicle stability system. The system includes at least one primary sensor and at least one secondary sensor for sensing the operation of at least one vehicle characteristic. The system calculates an estimated output of the primary sensor using at least one estimate model, and generates at least one residual as the difference between a measured output of the primary sensor and the estimated output of the estimate model. The system uses a residual pattern to determine if the primary sensor is faulty. The system compares the measured output of the primary sensor to a measured output of the secondary sensor if the residual is less than a threshold, and determines that the secondary sensor is faulty if the comparison between the measured outputs of the primary and secondary sensors is greater than a predetermined threshold.

Abstract: A control system and method for use in vehicles, such as automotive vehicles. The control system and method is particularly adapted for use in vehicles having by-wire control systems. The control system uses three system controllers. Each of the controllers is adapted to receive redundant control inputs from at least one input device, such as a steering actuator, an accelerator actuator and a brake actuator. Each controller is adapted to receive a different unprocessed actuator sensor signal and a processed actuator sensor signal which are associated with the input device. Each controller may also be adapted to receive a sensor status signal which is also associated with the input device. In accordance with the method of the invention, these signals may be used to determine a sensor signal which may be used as the basis for control of control systems or components in response to the input device.

Abstract: A brake control system for brake by wire applications having a dual fail-silent pair controller architecture. The system utilizes two supervisory controllers and a shared monitoring controller to achieve the dual fail-silent pair configuration. The brake control system also features a mechanism whereby the monitoring controller ensures the fail-silent operation of the brake control units in the event of certain undesired events occurring within the system by assuming control of the affected brake control units. The control system further assures that no single event, including an event related to the monitoring controller, causes loss of more than half the braking functionality. The control system also features additional redundancy with regard to the brake command signals by sharing a separate unprocessed brake command signal with each of the supervisory controllers and the monitoring controller.

Abstract: A device for and method of performing a task associated with fingerprint data is disclosed. The method comprises reading fingerprint data, matching the read fingerprint data to stored fingerprint data, the stored fingerprint data having an associated task, and performing the task. The associated task is part of a chain of tasks that are automatically executed when the read fingerprint data is matched to the stored fingerprint data. Preferably, at least one task has associated user profile data that is used to perform the task. An electronic device that can be controlled in accordance with the present invention includes, but is not limited to, a telephone, a personal computer, a personal digital assistant, and a remote controlled device.

Abstract: A rock stabilizer includes an elongated metal tube having and interior and an exterior surface with a distal end and a proximal end. The distal end is tapered and a flange is positioned adjacent the proximal end. The tube further includes a slit that runs substantially the entire length thereof. The tube is constructed so as to be capable of being positioned within a bore formed in the wall of a mine. A plurality of indentations or recesses are formed in the outer surface of the tube along the length thereof adjacent the slit so that grout or resinous material pumped into the interior of the tube can flow out of the slit and into the indentations or recesses. An expander wedge is also located within the interior of the tube adjacent the distal end and is actuatable from the proximal end of the tube after said stabilizer is installed in a bore. The wedge expands the distal end of the tube to firmly anchor the stabilizer in the bore.