Patents by Inventor Mark J. Cooper

Mark J. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identifying oncogenes and anti-oncogenes
    Patent number: 5770374
    Abstract: Episomal plasmids containing a papovavirus origin of replication and a papovavirus large T antigen mutant form are shown to replicate episomally in human cells, and yield levels of gene expression proportional to their episomal copy number. Candidate oncogenes and anti-oncogenes can be identified by transfecting the episomal plasmids containing a candidate oncogene or anti-oncogene into non-tumorigenic cells and screening for a tumorigenic phenotype.
    Type: Grant
    Filed: October 10, 1996
    Date of Patent: June 23, 1998
    Assignee: Case Western Reserve University
    Inventor: Mark J. Cooper
  • Episomal expression vector for human gene therapy
    Patent number: 5624820
    Abstract: Episomal plasmids containing a papovavirus origin of replication and a papovavirus large T antigen mutant form are shown to replicate episomally in human cells, and yield levels of gene expression proportional to their episomal copy number. In conjunction with liposomal or receptor-mediated delivery systems, papovavirus-derived episomal plasmids provide an alternative vector for gene therapy, particularly when utilizing strategies requiring high levels of gene expression.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 29, 1997
    Assignee: Case Western Reserve University
    Inventor: Mark J. Cooper
  • Pull-out keyboard tray
    Patent number: D437857
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: February 20, 2001
    Assignee: Accuride International, Inc.
    Inventors: Mark J. Cooper, Kristin M. Stewart