Abstract: A negative pressure wound therapy apparatus can include a housing, a negative pressure source supported by the housing and configured to aspirate fluid from a wound covered by a wound dressing, a switch positioned on an exterior surface of the housing, and a controller configured to operate the negative pressure source. The controller can be configured to, responsive to receiving a first user input via the switch, operate the negative pressure source to aspirate fluid from the wound at a first fluid flow rate. The controller can be configured to, responsive to receiving a second user input via the switch subsequent to receiving the first user input, operate the negative pressure source to aspirate fluid from the wound at a second fluid flow rate greater than the first fluid flow rate.

Abstract: The present invention relates to a method for increasing the activity and/or the yield of a recombinant vitamin K-dependent protein expressed in cell culture. The present invention further relates to uses and compositions of matter.

Abstract: Systems, devices, and process described facilitate use of a first user device communicatively coupled to a local area network (LAN) The first user device may include a first hardware processor configured to execute first, non-transient, computer instructions for facilitating a first seamless DVR engine configured to identify a first content. A second user device is also coupled to the LAN. The second user device may include a second hardware processor configured to execute second, non-transient, computer instructions for facilitating a second seamless DVR configured to identify a second content. Each of the seamless DVR engines may be configured to generate a common universal directory identifying the first content and the second content as being available for use by each of the first user device and the second user device. User devices may independently populate the common universal directory. The universal directory may identify a distinct status for the content.

Abstract: A valve with an internal member is disclosed which allows exhaled carbon dioxide to escape from a breathing circuit when the circuit gas pressure drops below a threshold pressure. The valve operates by occluding one or more ports under a relatively high pressure and opening the one or more ports under a relatively low pressure. The internal member is attached to the body of the valve at two or more locations on the internal member. The internal member moves in a direction perpendicular to the gas flow through the valve.

Abstract: A method including: obtaining an image of at least part of a substrate, wherein the image includes at least one feature manufactured on the substrate by a manufacturing process including a lithographic process and one or more further processes; determining one or more image-related metrics in dependence on a contour determined from the image, wherein one of the one or more image-related metrics is an edge placement error, EPE, of the at least one feature; and determining one or more control parameters of the lithographic process and/or the one or more further processes in dependence on the edge placement error, wherein at least one control parameter is determined so as to minimize the edge placement error of the at least one feature.

Abstract: A system on chip (102) comprising a plurality of logically homogeneous processor cores (104), each processor core comprising processing circuitry (210) to execute tasks allocated to that processor core, and task scheduling circuitry (202) configured to allocate tasks to the plurality of processor cores. The task scheduling circuitry is configured, for a given task to be allocated, to determine, based on at least one physical circuit implementation property associated with a given processor core, whether the given task is allocated to the given processor core.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, an activator layer such as an acid providing layer and nitric oxide source layer, such as a nitrite providing layer. The activator layer may include acidic groups and may be hydrogel, xerogel, or other suitable material. The nitric oxide source layer may include a nitrite salt. Nitrite ions of the nitric oxide source layer may react with the acidic groups of the activating layer to generate nitric oxide. The wound dressing may further include a composite layer, such as a layer with an acquisition distribution layer embedded within an activator gel layer. Additional composite layers may include various absorbent materials embedded within an activator gel layer.

Abstract: A wellbore system includes an upper body, a lower body, removably coupled to the upper body, and a passage extending through both the upper body and the lower body, the passage being aligned and extending through an interface between the upper body and the lower body. The wellbore system also includes a latch piston, confined to the lower body, the latch piston being moveable responsive to an applied pressure via the passage. The wellbore system further includes a latch piston retaining ring, confined to the lower body.

Abstract: A method and system for contouring a medical image in a contouring system is described. The method comprising the steps of: providing at least one medical image to be contoured by a user; determining that the user has initiated contouring of a structure on the medical image; the contouring system determining the structure that is being or will be contoured; in response to the determination of the structure the system displaying guidance for the contouring of the determined structure; contouring the determined structure in accordance with the displayed guidance. A method and system for reviewing contours on a contoured medical image is also described.

Abstract: A method and system for reviewing contouring of medical images in a contouring system is described. The method comprising the steps of: providing at least one medical image showing structures to be contoured; generating a contour for a structure on the at least one medical image; determining if the generated contour conforms to guidelines for the structure being contoured; in response to the determining of conformity providing feedback about the quality of the contour; and continuing to generate the contour based on the provided feedback. A method and system for reviewing previously contoured medical images is also described.

Abstract: A method and system for contouring an image for display is described. The method comprising: providing at least one image to be contoured; providing a window width parameter, W, and a window level parameter, L; displaying the medical image according the W,L parameters; performing the following steps: determining local image intensities of the at least one image for each position of the contour, as it is generated; determining if the parameters are suitable for each position of the contour on the image as it is generated; according to the determined local image intensity; if the parameters are not suitable, alerting the user that at least one of the parameters is not suitable for a most recently generated position on the contour; adjusting at least one of the—parameters to be suitable for the most recently generated position on the contour; and displaying the—image according to the adjusted settings.

Abstract: The invention relates to modified helicases with reduced unbinding from polynucleotides. The helicases can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.

Abstract: The present disclosure relates to syringe cartridges containing a predetermined quantity of a first drug (e.g., sodium bicarbonate having a low moisture content) and to syringe systems and kits containing the syringe cartridge. As described herein, the disclosed syringe cartridges, systems, and kits can be useful in, for example, administering a second drug (e.g., a caine such as lidocaine) and/or to reconstitute the first drug. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: Disclosed embodiments relate to a wound dressing which can generate nitric oxide. The wound dressing may include a cover layer, a nitric oxide source layer, such as a nitrite providing layer, an absorbent layer such as a foam, and a gel material adhered to the absorbent layer. The gel material may include perforations in a cured pattern structure. The perforations may define a plurality of fluid channels extending through the gel material. The gel material may form an active wound contact layer for use in generating nitric oxide.

Abstract: A system for generating and inferencing using enterprise knowledge graphs is provided. The system receives first input data related to one or more entities from one or more data sources. The system extracts a first set of data components from the first input data and determines, based upon the extracted data components, a second set of data components. The system identifies one or more relationships between the first set of data components and the second set of data components and generate a knowledge graph comprising a plurality of nodes. A first node of the knowledge graph can represent a first respective data component of the first set of data components and a second node of the knowledge graph can represent a second respective data component of the second set of data components. The first node can be associated with the second node based on an identified relationship between the nodes.

Abstract: Provided herein are methods and systems for identifying a related data values in a plurality of datasets. The method can include extracting data from the plurality of datasets, identifying potential linking categories, and determining a validity of the potential linking categories. One or more linking categories can be selected from the potential linking categories based on the validity, and related data values can be identified between the plurality of datasets based on the selected linking categories. Also provided herein are methods and systems for classifying data values as reconciled or non-reconciled. The method can include identifying a plurality of related data values in a plurality of datasets. For each of the plurality of related data values, a similarity score and confidence score can be determined, and the plurality of related data values can be classified as reconciled or non-reconciled based on the similarity score and/or the confidence score.

Abstract: Provided herein are methods and systems for determining a roll forward amount. The method can include identifying a starting balance, extracting reconciled data values from a database, each reconciled data value having a confidence score that indicates a confidence level that a reconciled data value of a first dataset is the same as a corresponding reconciled data value of a second dataset. The method can include identifying a first subset of the reconciled data values that are a first type and a second subset of the reconciled data values that are a second type, and determining a roll forward amount based on the starting balance, the first subset, and the second subset.

Abstract: The present disclosure relates to herbicidal combinations and their use in controlling plants or inhibiting plant growth. In particular, herbicidal combinations comprising pyridafol in combination with at least one further herbicide that is a HPPD-inhibitor herbicide.

Abstract: A biopharmaceutical flow port, a biopharmaceutical liquid container assembly, and a method for manufacturing the biopharmaceutical flow port and the biopharmaceutical liquid container assembly are described. The biopharmaceutical flow port includes a hose barb coupled to an elliptic body. The hose barb includes a bore. The elliptic body includes a flow passage, a first edge, and a second edge. The flow passage is fluidly coupled to the bore. The first edge extends from the elliptic body away from the flow passage in a first direction and the second edge extends from the elliptic body away from the flow passage in a second direction opposite the first direction. The biopharmaceutical liquid container assembly includes a biopharmaceutical liquid container with an opening and the biopharmaceutical flow port coupled to the biopharmaceutical liquid container within the opening and in fluid communication with a volume of the biopharmaceutical liquid container.