Abstract: The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.

Abstract: The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.

Abstract: A method and apparatus for welding two separate ends of an extrusion or two separate extrusion ends to form a flashless extrudate or gasket by having a first and a second mold for supporting and clamping the extrusion ends, and a spacer bar for positioning the extrusion ends to a location within the mold. A heating element elevates the temperature of the extrusion ends to a welding condition, and a clamping device is used for securing the extrusion ends. A flashless welding operation results by inserting and clamping at least one heated extrusion end into a welding mold until an acceptable contact pressure is obtained against the opposing heated extrusion end.

Abstract: A method and apparatus for welding two separate ends of an extrusion or two separate extrusion ends to form a flashless extrudate or gasket by having a first and a second mold for supporting and clamping the extrusion ends, and a spacer bar for positioning the extrusion ends to a location within the mold. A heating element elevates the temperature of the extrusion ends to a welding condition, and a clamping device is used for securing the extrusion ends. A flashless welding operation results by inserting and clamping at least one heated extrusion end into a welding mold until an acceptable contact pressure is obtained against the opposing heated extrusion end.

Abstract: A permanently lubricated film gasket for providing a fluid-tight seal between a corrugated pipe and a smooth annular section of an outer pipe or section when the corrugated pipe and the outer pipe or section are in a relative surrounded and surrounding relationship. A first portion of the gasket is shaped to fit within a groove or recess of the corrugated pipe. A second portion of the gasket extends from the first portion. The second portion is at least partially comprised of permanently lubricated film for facilitating in the connection of the pipes along a single direction.

Abstract: A permanently lubricated film gasket for providing a fluid-tight seal between a corrugated pipe and a smooth annular section of an outer pipe or section when the corrugated pipe and the outer pipe or section are in a relative surrounded and surrounding relationship. A first portion of the gasket is shaped to fit within a groove or recess of the corrugated pipe. A second portion of the gasket extends from the first portion. The second portion is at least partially comprised of permanently lubricated film for facilitating in the connection of the pipes along a single direction.

Abstract: A gasket is provided that forms a sealing connection between a pair of tubular members. The gasket comprises a first section shaped to fit within a recess of one of a pair of tubular members. The first section includes an anchor portion comprising first and second sides. The gasket further comprises a second section extending from the first section and is configured to make a sealing contact with the other of the tubular members. The gasket also includes at least one self-locating arm in a sealing contact within the recess and extending from one of the first or second sides of the anchor portion of the first section. The self-locating arm biases the first section such that the other of the first or second sides is in contact with the recess to form a sealing connection.

Abstract: The present invention is directed to an annular gasket for providing a fluid-tight seal between an inner pipe and an outer pipe, when the pipes are in a relative surrounded and surrounding relationship. The gasket includes a gasket portion configured to sealingly engage the inner and outer pipes when the pipes are in a relative surrounded and surrounding relationship. The gasket includes a low coefficient of friction surface which is applied to the gasket portion. The gasket may be formed by a method in which a low coefficient of friction film is inserted into a mold before injection of compounds used to form the gasket.

Abstract: A method and apparatus for welding two separate ends of an extrusion or two separate extrusion ends to form a flashless extrudate or gasket by having a first and a second mold for supporting and clamping the extrusion ends, and a spacer bar for positioning the extrusion ends to a location within the mold. A heating element elevates the temperature of the extrusion ends to a welding condition, and a clamping device is used for securing the extrusion ends. A flashless welding operation results by inserting and clamping at least one heated extrusion end into a welding mold until an acceptable contact pressure is obtained against the opposing heated extrusion end.

Abstract: A permanently lubricated film gasket for providing a fluid-tight seal between a corrugated pipe and a smooth annular section of an outer pipe or section when the corrugated pipe and the outer pipe or section are in a relative surrounded and surrounding relationship. A first portion of the gasket is shaped to fit within a groove or recess of the corrugated pipe. A second portion of the gasket extends from the first portion. The second portion is at least partially comprised of permanently lubricated film for facilitating in the connection of the pipes along a single direction.

Abstract: The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds.

Abstract: The invention involves a T-post bracket allowing rapid and easy attachment of bracing T-posts to stanchion T-posts for fencing, trellis, or similar applications, and/or rapid and easy attachment of gates or other swinging structures to stanchion T-posts affixed to the bracket. The bracket has one end wherein a stanchion insertion space is provided between a stop member and a pair of retaining tabs, and insertion of a stanchion engagement fastener (e.g., a pin) engages the stanchion within the stanchion insertion space. Engagement legs may extend from the retaining tabs, and a bracing T-post may be fit between the engagement legs and pinned therein by insertion of brace engagement fasteners. Additionally or alternatively, a hinge post may extend from the bracket from a point about the stanchion insertion space, preferably from the stop member, to allow hanging of a gate or other swinging structure from the hinge post (and thus from a stanchion situated within the stanchion insertion space).

Abstract: A permanently lubricated annular gasket for providing a fluid-tight seal between a corrugated pipe and a smooth annular section of an outer pipe or section when the corrugated pipe and the outer pipe or section are in a relative surrounded and surrounding relationship. A first portion of the gasket is shaped to fit within a groove or recess of the corrugated pipe. A second portion of the gasket extends from the first portion. The second portion is at least partially comprised of permanently lubricated thermoplastic material. The second portion is configured to make sealing contact with the outer pipe or section when the corrugated pipe and the outer pipe or section are in a relative surrounded and surrounding relationship.

Abstract: An annular gasket for providing a fluid-tight seal between a corrugated pipe and a smooth annular section of a second member. The gasket includes a support portion and a gasket portion. The support portion is made from a first material having a first hardness. The support portion includes an anchor portion shaped to fit within a recess or groove in a first member and a tip portion that extends radially outward from the anchor portion. The gasket portion is made from a softer elastomeric material. The gasket portion is disposed on the tip portion. The gasket portion is configured to make sealing contact with a ridge of the first pipe and the smooth annular section when the first pipe and the smooth annular section are in a relative surrounded and surrounding relationship.

Abstract: An annular gasket for providing a fluid-tight seal between a corrugated pipe and a smooth annular section of a second member. The gasket includes a support portion and a gasket portion. The support portion is made from a first material having a first hardness. The support portion includes an anchor portion shaped to fit within a recess or groove in a first member and a tip portion that extends radially outward from the anchor portion. The gasket portion is made from a softer elastomeric material. The gasket portion is disposed on the tip portion. The gasket portion is configured to make sealing contact with a ridge of the first pipe and the smooth annular section when the first pipe and the smooth annular section are in a relative surrounded and surrounding relationship.

Abstract: A locking annular gasket, for providing a seal between a tubular member and a smooth annular section, includes an annular gasket portion and a locking member. The annular gasket portion seals a gap between the smooth annular section and the tubular member. The locking member is secured to the gasket portion for holding the gasket portion in place while the tubular member and the smooth annular section are assembled.

Abstract: A compressible annular gasket for providing a fluid-tight seal between a first tubular member having an annular groove and an adjacent ridge and a smooth annular section of a second tubular member when the first tubular member and the smooth annular section are in a relative surrounding and surrounded relationship. The compressible annular gasket includes an anchor portion adapted to be disposed in the annular groove and an elongated portion adapted to extend across the adjacent ridge when the anchor portion is disposed in an adjacent groove. The elongated portion makes contact with the annular section when the first tubular member and the smooth annular section are in a relative surrounded and surrounding relationship.

Abstract: A pedal-powered boat that uses a flexible shaft to drive a propeller. By using a flexible shaft, the user's seat can be placed lower in the vessel, thereby increasing stability. The device also uses a pair of foot pegs and a ratcheted straight driver, which eliminates standard pedals, with their sweeping circular motion. This straight drive not only increases the efficiency of the leg power, it also converts the rotary action of the pedals to a linear motion that reduces the amount of space required to operate the unit. Thus, the driver unit can be placed under a seat so that it does not excessively intrude into the space of the boat.