Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

Abstract: Graphitic nanotubes, which include tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

Abstract: An assay apparatus includes a cell with a working electrode and a sonicating device structurally coupled to the cell for sonication the contents of the cell.

Abstract: The specification discloses a combination cheering aid and seat cushion, comprising a substantially planar seating member formed of a flexibly resilient and flexibly compressible material, the seating member including opposite upper and lower surfaces, opposite first and second lateral portions, and opposite front and rear portions, and complementary fastening elements. The seating member is characterized by a first configuration adapted for use as a seat cushion, wherein the seating member is in the substantially planar condition thereof, and a second configuration adapted for use as a cheering aid, wherein the opposite first and second lateral portions are removably connected by the complementary fastening elements to thereby define a tubular configuration of the seating member characterized by an interior passageway communicating opposing first and second openings defined by the front and rear portions, respectively.

Abstract: The present invention concerns a novel means by which liquids can be moved or mixed. Microwaves strike and heat materials that are highly susceptible to microwave heating. The susceptible materials are on, within, or near materials that melt or change shape in response to temperature increases. Upon microwave irradiation, these materials change shape (e.g., shrink or melt), causing the movement of liquids. The invention is important in many microfluidics applications, especially in biomedical analysis, where it is valuable to be able to move small volumes of liquids (e.g., on a microarray chip).

Abstract: Described herein are temperature-controllable devices, and methods for using them. In some variations, the devices comprise a fluid passageway region, which is configured to allow a fluid to flow therethrough, and a splint. The splint may be moldable to at least a portion of a subject's anatomy, e.g., a nose. In other variations, the devices comprise a fluid passageway region configured to allow a fluid to flow therethrough, and an absorbent pad. In some variations, the devices comprise three layers, in which two of the layers form a fluid passageway region and the third layer forms a pocket or pouch. In this way, the pouch may be configured to receive at least one splint therein, e.g., in order to provide support to an injured area such as a nose. Methods for using the devices to treat an injured area are also described. Kits are also described.

Abstract: A method of generating a electrochemiluminescent emission, which comprises exposing an electrochemiluminescent label linked to a coreactant, to conditions suitable for inducing electrochemiluminescence; said compound; a system for generating an electrochemiluminescent emission, which comprises said compound, means for exposing said compound to electrochemical energy, and means for detecting or measuring luminescence emitted from said compound or a composition containing same; and a kit for performing an assay using said compound.

Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.

Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.

Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.

Abstract: Disclosed and claimed are prodrugs activated by catalytic proteins, such as enzymes and catalytic antibodies. The invention comprehends such prodrugs, as well as haptens, to elicit catalytic antibodies to activate the prodrugs. The prodrugs are useful as cytotoxic chemotherapeutic agents; e.g., as antitumor agents.

Abstract: Graphitic nanotubes, which includes tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution or by adsorption of functional moieties. More specifically the invention relates to graphitic nanotubes which are uniformly or non-uniformly substituted with chemical moieties or upon which certain cyclic compounds are adsorbed and to complex structures comprised of such functionalized nanotubes linked to one another. The invention also relates to methods for introducing functional groups onto the surface of such nanotubes. The invention further relates to uses for functionalized nanotubes.

Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

Abstract: Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

Abstract: A system and method for providing universal mobile device access to information without requiring separate applications for each requesting mobile device. Generally, the system comprises an enterprise backend having the requested information stored therein. The system also comprises a universal server connected to the enterprise backend for receiving a request for the information from the mobile device, and for providing the mobile device with the information from the enterprise backend. The universal server does not require separate software applications to customize display of the information for each different category of mobile device requesting information.

Abstract: A system and method for formatting information requested by a mobile communication device for display on the mobile communication device. A category of the requesting mobile communication device is first determined. The requested information is then formatted in accordance with at least one mobile application markup language category file that is specific to the category of the mobile communication device, wherein the mobile application markup language category file is utilized to convert the received information into a mobile application markup language device file that may be displayed by mobile communication devices that are the same category as the determined category of the requesting mobile communication device.

Abstract: Compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the invention relates to the use of novel combinations of reagents to provide improved assay performance.