Abstract: A method includes processing live image data captured by a camera associated with a first device. The live image data is displayed by the first device. A video displayed by a second device is viewable within the live image data displayed by the first device. The live image data is processed to identify a spatial position of the video displayed with respect to the camera associated with the first device within the live image data, and to identify a known frame of the video. The method also includes causing augmented imagery to be displayed by the first device in a display area of the first device within which the live image data is displayed concurrently with the video displayed by the second device. The augmented imagery is displayed in the display area of the first device based on the identified spatial position, and in response to the known frame.

Abstract: The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.

Abstract: Apparatuses, systems, and methods comprising acoustically absorptive air ducts comprising an internally positioned structure component as an endoskeleton and an air impervious inner layer, and an acoustically absorptive foam outer layer, environmental control systems comprising such air ducts, and vehicles incorporating such environmental control systems are disclosed with methods for manufacture and installations are disclosed.

Abstract: The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.

Abstract: Apparatuses, systems, and methods comprising acoustically absorptive air ducts comprising an internally positioned structure component as an endoskeleton and an air impervious inner layer, and an acoustically absorptive foam outer layer, environmental control systems comprising such air ducts, and vehicles incorporating such environmental control systems are disclosed with methods for manufacture and installations are disclosed.

Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blocking agent and a CD38 antibody such as daratumumab. The anti-cancer effect of SIRP?Fc is enhanced in the presence of daratumumab. Specific combinations include SIRP?Fc forms that comprise an Fc that is either IgG1 or IgG4 isotype. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.

Abstract: An aqueous emulsion system substantially or completely devoid of an oil phase. The aqueous emulsion can be used as a platform to solubilize poorly water-soluble chemical compounds for use in a variety of fields, including pharmaceutical, cosmetic, skin care, personal care, food, and industrial arenas. The aqueous emulsion can be delivered to a human or animal via a variety of modes to treat a diverse number of ailments, such as a topical composition to promote hair growth or treat skin disorders. Stable and transparent formulations of the aqueous nano-emulsions described herein can be used to treat and/or prevent hair loss, to treat warts and cold sores, or to treat varicose veins.

Abstract: An intraocular lens (IOL) prosthesis is implanted through one or more corneal incisions made within a predetermined surgical axis defining a plane that intersects the optical axis as well as the visual axis of the human eye. At least two looped sutures are fed through suture apertures and sutured to the sclera of the eye by which a center aperture of the prosthesis is suspended in the plane within the posterior chamber of the eye and centered on either the optical or visual axis. The prosthesis is made of a thin sheet of flexibly resilient material (e.g. silicone, polyimide, acrylic, polypropylene), and can be rectangular, triangular or of any suitable geometric shape. The center aperture has dimensions that facilitates optic capture or reverse optic capture of commercially available IOLs and includes vertex features for resisting movement of the haptics of the captured IOLs once captured therein.

Abstract: A thermal shield flexure member. The thermal shield flexure member includes a first face portion, a second face portion and a third portion. The first face portion defines openings configured to align with receptacles of a thermal shield. The second face portion defines openings configured to align with openings of a core barrel and openings of an arm portion of a modified thermal shield flexure connected to the core barrel. The third portion is connected to the first face portion and the second face portion, and comprises a radiused portion. The thermal shield flexure member is configured to provide flexibility in an axial direction to accommodate differential axial expansions of the core barrel and the thermal shield, and rigidity in a radial direction to inhibit undesirable shell mode vibrations of the core barrel and/or the thermal shield.

Abstract: A system includes a loading/unloading facility, a user apparatus having a user interface configured to communicate with a driver of a delivery/pick-up vehicle, and an administrator apparatus configured to communicate with the user apparatus and the loading/unloading facility. The driver checks into the user apparatus and the administrator apparatus coordinates arrival of the delivery/pick-up vehicle at the loading/unloading facility. The driver may check in at the user apparatus without touching the user apparatus and without exiting the vehicle. The driver may receive shipping documents from the user apparatus and may electronically sign the shipping documents without exiting the vehicle.

Abstract: Multi-filament microcables are used in place of the traditional monofilament wires as the constituent elements of a woven or braided band. This enhances the function and manufacturability of such bands for various applications, such as orthopaedic applications including sternotomy closures.

Abstract: Gear devices and methods for operating gear devices are provided. In one example, a gear device is provided that comprises structures designed to attenuate targeted vibrations occurring during rotation of the gear device. The structures includes radially aligned struts extending between an inner carrier and an outer carrier, a plurality of openings arranged between the struts, and/or resonators extending between sequential struts.

Abstract: The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.

Abstract: A capsular prosthesis is disclosed that is implanted to support posterior chamber placement of IOLs. The capsular prosthesis can be implanted to replace the capsule in situations where the patient's natural capsule has been rendered incapable of providing the structural support necessary to maintain proper centration of an IOL implanted therein. The prosthesis is surgically implanted into the eye by inserting the prosthesis into the eye through a primary incision. The prosthesis is secured to the sclera of the eye with at least two transscleral sutures to establish at least three points of contact between the sclera and the at least three apertures of the prosthesis. The at least two transscleral sutures support the sheet within a desired plane located within the posterior chamber, the plane containing a predetermined surgical axis passing through the center aperture. The IOL is inserted through the primary incision and optically captured on the prosthesis.

Abstract: The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.

Abstract: An automated laboratory system includes a vertical shelving system including a frame and at least one shelf movably mounted to the frame such that the at least one shelf is movable relative to the frame between a docked position and an undocked position, the at least one shelf being configured to carry at least one instrument. The system also includes a robotic device proximate the vertical shelving system and being configured to access the at least one instrument carried by the at least one shelf.

Abstract: Methods and systems are provided for a turbine integrally formed with a cylinder head. In one example, a system includes a cylinder head and a turbine shaped from a single, continuous piece of metal.

Abstract: Gear devices and methods for operating gear devices are provided. In one example, a gear device is provided that comprises structures designed to attenuate targeted vibrations occurring during rotation of the gear device. The structures includes radially aligned struts extending between an inner carrier and an outer carrier, a plurality of openings arranged between the struts, and/or resonators extending between sequential struts.

Abstract: A process for producing a solid dispersion of a material by spraying the material onto a fluidized cloud of carrier particles in a fluid bed. The fluidized cloud of carrier particles is formed by adding a solid or liquid carrier to a fluid bed. The material to be sprayed is in a liquid or gas form. The process is especially applicable to the formation of amorphous solid powder pharmaceutical ingredients.