Abstract: A container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching assemblies. The latching assembly may comprise a latch body, a locking member, a biasing member, and an activating member. Additional features of the container may include handles and strength increasing features. The base and lid may also feature attachment points for various accessories. A carry strap may attach to the base of the container to allow a user to lift and carry the container. The container may also have a wheels attached to the bottom portion and/or across the bottom portion to one side of the sidewall structure. In addition, in exemplary containers with wheels, a pull handle may be attached to a side opposite the wheels. The lid may include a lid support member that can act as a molle board to releasably secure items to the lid support member while also providing structural support to the lid.

Abstract: A container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching assemblies. The latch assembly may comprise a latch body, a locking member, a biasing member, and an activating member. The lid may have a handle that has a stowed and a carry position, where the handle may be maintained in the stowed position until acted upon by a first force greater than a threshold force to move the handle from the stowed position to the carry position. Similarly, when in the carry position, the handle may be maintained in the carry position until acted upon by a second force greater than the threshold force to move the handle from the carry position to the stowed position.

Abstract: We provide an ostomy collection device including: a housing defining a collecting volume for receiving and storing waste from an ostomy appliance, the housing including an inlet for fluidly connecting to an outlet of an ostomy appliance so that waste from the ostomy appliance flows into the collecting volume; and a cover layer positioned over an external surface of the housing.

Abstract: An ostomy collection device (10) including: a housing (12) which defines a collection volume for holding waste, and a connector member (30) for connection to an ostomy appliance, having an inlet (40) and an outlet (42) fluidly connected to the collection volume, said connector member (30) being pivotably and/or rotatably supported relative to the housing (12).

Abstract: A housing of a device comprises a screw boss that extends outwardly from a first base plate proximate to a corner of the housing. Additionally, the housing of the device includes a force dissipation member. The force dissipation member includes a central portion that is sized to detachably attach around the screw boss. The force dissipation member further includes at least two arms that extend outwardly from the central portion, wherein each arm of the at least two arms is attached to a different side of the two walls of the housing.

Abstract: A container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching assemblies. The latch assembly may comprise a latch body, a locking member, a biasing member, and an activating member. The lid may have a handle that has a stowed and a carry position, where the handle may be maintained in the stowed position until acted upon by a first force greater than a threshold force to move the handle from the stowed position to the carry position. Similarly, when in the carry position, the handle may be maintained in the carry position until acted upon by a second force greater than the threshold force to move the handle from the carry position to the stowed position.

Abstract: Cryogenic analysis assemblies and methods are provided. The assemblies and/or methods can be configured for optical sample analysis. The assemblies and/or methods can include: an objective assembly operatively aligned with a sample support assembly, both the objective assembly and sample support assembly residing within a vacuum housing; wherein the objective assembly defines an objective mount housing an objective coupled to a mounting ring within a chamber below a heater assembly; and an insulative member between the objective mount and the mounting ring, the insulative member supporting the objective mount and thermally isolating the objective mount from the mounting ring.

Abstract: A rotor for a turbomachine and a method of manufacturing the same. The method includes providing a lug with a lug body and an interface material disposed on the lug body. The method also includes friction welding the lug to a hub member via the interface material to define a projected structure for an outer radial area of a disc assembly of the rotor. The projected structure is configured to support a first side of a rotor blade of the rotor in cooperation with a second projected structure of the disc assembly supporting a second side of the rotor blade. The lug body and the hub member are made from different materials.

Abstract: A turbine vane airfoil and a turbine nozzle that includes the turbine vane airfoil. The turbine vane airfoil includes an airfoil defining a chamber proximate a surface, and an impingement tube. The impingement tube includes a first wall and a second wall. The first wall defines a plurality of first apertures, and each has a first upstream surface portion opposite a first downstream surface portion. The second wall defines a plurality of second apertures, and each has a second upstream surface portion opposite a second downstream surface portion. Each of the first apertures cooperate with a respective one of the second apertures to direct a cooling fluid onto the surface, and the first downstream surface portion of at least one of the first apertures includes a first point that is collinear with a second point of the second downstream surface portion of the respective one of the second apertures.

Abstract: The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Abstract: Provided herein are efficient and scalable methods for the synthesis of nicotinamide riboside from riboside triacetate. Also provided are compositions comprising nicotinamide riboside, and therapeutic methods employing nicotinamide riboside.

Abstract: Novel compounds, compositions, and methods of using and preparing the same, which maybe useful for treating alpha-1 antitrypsin deficiency (AATD).

Abstract: The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Abstract: Infant formula compositions and methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.

Abstract: A function reference for a function is identified in a query. A plurality of processing environments that can provide the function is identified. Function costs for the function to process in the processing environments are obtained. Input data transfer costs are acquired for providing input data identified in the query to each of the functions. A specific one of the functions from a specific processing environment is selected based on the function costs and the input data transfer costs. A query execution plan for executing the query with the specific function is generated. The query execution plan is provided to a database engine for execution.

Abstract: Provided herein are efficient and scalable methods for the synthesis of nicotinamide riboside from riboside triacetate. Also provided are compositions comprising nicotinamide riboside, and therapeutic methods employing nicotinamide riboside.

Abstract: Provided herein are crystalline forms of nicotinamide riboside chloride and methods of making the same. Also provided are compositions comprising the crystalline form of nicotinamide riboside chloride, and therapeutic methods employing the crystalline form of nicotinamide riboside chloride.

Abstract: An impingement baffle for directing a cooling fluid onto a target surface includes a baffle body having a first end opposite a second end, and a first side opposite a second side. The second side is spaced a distance apart from the target surface, with the distance varying from the first end to the second end. The baffle body defines impingement holes that extend through the baffle body from the first side to the second side. The impingement holes are spaced apart along the baffle body to receive the cooling fluid. The impingement baffle includes tubular extensions coupled to the second side. Each tubular extension is in fluid communication with a respective one of the impingement holes to direct the cooling fluid onto the target surface. Each tubular extension extends for a length from the second side, and the length of each tubular extension is based on the distance.

Abstract: Methods for delivering at least one compound selected from nicotinamide riboside (NR), nicotinic acid riboside (NAR), and nicotinamide mononucleotide (NMN), derivatives thereof, or salts thereof, in combination with at least one of thiamine (vitamin B1), riboflavin (vitamin B2), niacin (vitamin B3), and pyridoxine (vitamin B6), to an infant human subject in need of said compound or compounds are provided.