Patents by Inventor Mark Noble

Mark Noble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12059497
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: August 13, 2024
    Assignee: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark E Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Publication number: 20230285299
    Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.
    Type: Application
    Filed: April 14, 2023
    Publication date: September 14, 2023
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: John Elfar, Kuang-Ching Tseng, Mark Noble
  • Patent number: 11756017
    Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: September 12, 2023
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
  • Patent number: 11654110
    Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: May 23, 2023
    Assignee: UNIVERSITY OF ROCHESTER
    Inventors: John Elfar, Kuang-Ching Tseng, Mark Noble
  • Patent number: 11138584
    Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: October 5, 2021
    Assignee: Mantissa Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
  • Patent number: 11087318
    Abstract: Improved checkout systems, apparatuses and methods for managing electronic coupons include a checkout kiosk, a point-of-sale system and a microprocessor with an electronic rules engine. The electronic rules engine is configured to allow application of electronic coupons to customer accounts internally to the point-of-sale system. Redemption of the electronic coupons is allowed by the consumer at the kiosk without a scan-able artifact.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: August 10, 2021
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Burt Aycock, Mark Noble, Matthew James Mellon
  • Publication number: 20210008164
    Abstract: This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.
    Type: Application
    Filed: June 26, 2020
    Publication date: January 14, 2021
    Inventors: John Elfar, Walaa Elfar, Mark Noble
  • Patent number: 10762485
    Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: September 1, 2020
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
  • Patent number: 10695402
    Abstract: This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: June 30, 2020
    Assignee: UNIVERSITY OF ROCHESTER
    Inventors: John Elfar, Walaa Elfar, Mark Noble
  • Publication number: 20200093746
    Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.
    Type: Application
    Filed: November 26, 2019
    Publication date: March 26, 2020
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: John Elfar, Kuang-Ching Tseng, Mark Noble
  • Patent number: 10248942
    Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: April 2, 2019
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John White, Burt Aycock, Claire McRoberts
  • Patent number: 10089614
    Abstract: A checkout system includes a checkout station having a housing, an attendant work station, a customer unloading station and an exceptions processing subsystem. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner and in communication with the exceptions processing subsystem. The attendant work station may include an exceptions handling display: Check out methods and apparatus are also disclosed.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: October 2, 2018
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John White, Burt Aycock, Claire McRoberts, Joe Jensen
  • Publication number: 20180271847
    Abstract: Compositions and methods of treating a subject with an acute traumatic injury are disclosed. The methods include administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a potassium channel blocker. The potassium channel blocker can include 4-aminopyridine, a derivative thereof, or a combination thereof. The pharmaceutical composition can be administered with an additional therapeutic agent such as an anticonvulsant. The methods can be used for treating acute traumatic injury to an excitable tissue. The methods can restore at least a portion of lost motor function or sensory function, enhance repair and regeneration of stem or progenitor cells such as to promote neural cell generation, enhance cell survival, reduce scarring, decreases sox9 expression, chondroitin sulfate proteoglycan expression, and other markers of tissue damage, decreases lesion size, decreases oxidative damage, or combinations thereof.
    Type: Application
    Filed: September 30, 2016
    Publication date: September 27, 2018
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: Mark NOBLE, Christoph PRĂ–SCHEL, Heather NATOLA, John C. ELFAR, Kuang-Ching TSENG, Li YUE
  • Publication number: 20180264083
    Abstract: This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.
    Type: Application
    Filed: March 16, 2018
    Publication date: September 20, 2018
    Applicant: University of Rochester
    Inventors: John Elfar, Walaa Elfar, Mark Noble
  • Publication number: 20180256503
    Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.
    Type: Application
    Filed: May 10, 2018
    Publication date: September 13, 2018
    Applicant: UNIVERSITY OF ROCHESTER
    Inventors: John Elfar, Kuang-Ching Tseng, Mark Noble
  • Patent number: 10043168
    Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: August 7, 2018
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
  • Publication number: 20180171288
    Abstract: Compositions and methods of treating a subject with cancer are described. The methods include administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a compound with the dual characteristics or restoring function of the c-Cbl ubiquitin ligase in cancer cells and in also worsening sublethal lysosomal dysfunction, preferably in combination with an agent capable of making cancer cells more oxidized. The pharmaceutical composition can be administered with an additional therapeutic agent or agents such as an agent that represents an accepted standard of care for the treatment of a particular type being treated. The methods can be used for treating a wide variety of different kinds of cancers, such as brain tumors, breast cancers, melanomas, breast cancers and lymphomas.
    Type: Application
    Filed: November 21, 2017
    Publication date: June 21, 2018
    Inventors: Mark Noble, Brett Stevens, Hsing-Yu Chen, Jennifer Stripay, Christopher Folts, Nicole Scott
  • Patent number: 9993429
    Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 12, 2018
    Assignee: University of Rochester
    Inventors: John Elfar, Kuang-Ching Tseng, Mark Noble
  • Patent number: 9926060
    Abstract: A marine outboard engine for a watercraft has a stern bracket for mounting the marine outboard engine to the watercraft, a swivel bracket pivotally connected to the stern bracket about a generally horizontal tilt/trim axis, and a drive unit pivotally connected to the swivel bracket about a steering axis. The steering axis is generally perpendicular to the tilt/trim axis. A hydraulic actuator is operatively connected to the stern bracket and the swivel bracket for pivoting the swivel bracket and the drive unit relative to the stern bracket about the tilt/trim axis. A pump is mounted to the swivel bracket. The pump is pivotable about the tilt/trim axis together with the swivel bracket. The pump is fluidly connected to the hydraulic actuator to supply hydraulic fluid to the hydraulic actuator.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: March 27, 2018
    Assignee: BRP US INC.
    Inventors: Darrell Wiatrowski, Mark Whiteside, George Broughton, Mark Noble
  • Patent number: 9595029
    Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: March 14, 2017
    Assignee: ECR Software Corporation
    Inventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts