Patents by Inventor Mark Noble
Mark Noble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12059497Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.Type: GrantFiled: March 22, 2021Date of Patent: August 13, 2024Assignee: Ipsen Biopharm Ltd.Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark E Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
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Publication number: 20230285299Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.Type: ApplicationFiled: April 14, 2023Publication date: September 14, 2023Applicant: UNIVERSITY OF ROCHESTERInventors: John Elfar, Kuang-Ching Tseng, Mark Noble
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Patent number: 11756017Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.Type: GrantFiled: March 18, 2021Date of Patent: September 12, 2023Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
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Patent number: 11654110Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.Type: GrantFiled: November 26, 2019Date of Patent: May 23, 2023Assignee: UNIVERSITY OF ROCHESTERInventors: John Elfar, Kuang-Ching Tseng, Mark Noble
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Patent number: 11138584Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.Type: GrantFiled: August 13, 2020Date of Patent: October 5, 2021Assignee: Mantissa CorporationInventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
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Patent number: 11087318Abstract: Improved checkout systems, apparatuses and methods for managing electronic coupons include a checkout kiosk, a point-of-sale system and a microprocessor with an electronic rules engine. The electronic rules engine is configured to allow application of electronic coupons to customer accounts internally to the point-of-sale system. Redemption of the electronic coupons is allowed by the consumer at the kiosk without a scan-able artifact.Type: GrantFiled: August 13, 2020Date of Patent: August 10, 2021Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Burt Aycock, Mark Noble, Matthew James Mellon
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Publication number: 20210008164Abstract: This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.Type: ApplicationFiled: June 26, 2020Publication date: January 14, 2021Inventors: John Elfar, Walaa Elfar, Mark Noble
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Patent number: 10762485Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.Type: GrantFiled: June 29, 2017Date of Patent: September 1, 2020Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
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Patent number: 10695402Abstract: This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.Type: GrantFiled: March 16, 2018Date of Patent: June 30, 2020Assignee: UNIVERSITY OF ROCHESTERInventors: John Elfar, Walaa Elfar, Mark Noble
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Publication number: 20200093746Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.Type: ApplicationFiled: November 26, 2019Publication date: March 26, 2020Applicant: UNIVERSITY OF ROCHESTERInventors: John Elfar, Kuang-Ching Tseng, Mark Noble
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Patent number: 10248942Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.Type: GrantFiled: February 6, 2017Date of Patent: April 2, 2019Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Mark Noble, John White, Burt Aycock, Claire McRoberts
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Patent number: 10089614Abstract: A checkout system includes a checkout station having a housing, an attendant work station, a customer unloading station and an exceptions processing subsystem. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner and in communication with the exceptions processing subsystem. The attendant work station may include an exceptions handling display: Check out methods and apparatus are also disclosed.Type: GrantFiled: August 26, 2014Date of Patent: October 2, 2018Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Mark Noble, John White, Burt Aycock, Claire McRoberts, Joe Jensen
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Publication number: 20180271847Abstract: Compositions and methods of treating a subject with an acute traumatic injury are disclosed. The methods include administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a potassium channel blocker. The potassium channel blocker can include 4-aminopyridine, a derivative thereof, or a combination thereof. The pharmaceutical composition can be administered with an additional therapeutic agent such as an anticonvulsant. The methods can be used for treating acute traumatic injury to an excitable tissue. The methods can restore at least a portion of lost motor function or sensory function, enhance repair and regeneration of stem or progenitor cells such as to promote neural cell generation, enhance cell survival, reduce scarring, decreases sox9 expression, chondroitin sulfate proteoglycan expression, and other markers of tissue damage, decreases lesion size, decreases oxidative damage, or combinations thereof.Type: ApplicationFiled: September 30, 2016Publication date: September 27, 2018Applicant: UNIVERSITY OF ROCHESTERInventors: Mark NOBLE, Christoph PRĂ–SCHEL, Heather NATOLA, John C. ELFAR, Kuang-Ching TSENG, Li YUE
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Publication number: 20180264083Abstract: This invention relates to treating gastrointestinal dysfunction with erythropoietin (EPO) or its analog.Type: ApplicationFiled: March 16, 2018Publication date: September 20, 2018Applicant: University of RochesterInventors: John Elfar, Walaa Elfar, Mark Noble
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Publication number: 20180256503Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.Type: ApplicationFiled: May 10, 2018Publication date: September 13, 2018Applicant: UNIVERSITY OF ROCHESTERInventors: John Elfar, Kuang-Ching Tseng, Mark Noble
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Patent number: 10043168Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.Type: GrantFiled: June 30, 2017Date of Patent: August 7, 2018Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts
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Publication number: 20180171288Abstract: Compositions and methods of treating a subject with cancer are described. The methods include administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising a compound with the dual characteristics or restoring function of the c-Cbl ubiquitin ligase in cancer cells and in also worsening sublethal lysosomal dysfunction, preferably in combination with an agent capable of making cancer cells more oxidized. The pharmaceutical composition can be administered with an additional therapeutic agent or agents such as an agent that represents an accepted standard of care for the treatment of a particular type being treated. The methods can be used for treating a wide variety of different kinds of cancers, such as brain tumors, breast cancers, melanomas, breast cancers and lymphomas.Type: ApplicationFiled: November 21, 2017Publication date: June 21, 2018Inventors: Mark Noble, Brett Stevens, Hsing-Yu Chen, Jennifer Stripay, Christopher Folts, Nicole Scott
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Patent number: 9993429Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.Type: GrantFiled: March 13, 2014Date of Patent: June 12, 2018Assignee: University of RochesterInventors: John Elfar, Kuang-Ching Tseng, Mark Noble
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Patent number: 9926060Abstract: A marine outboard engine for a watercraft has a stern bracket for mounting the marine outboard engine to the watercraft, a swivel bracket pivotally connected to the stern bracket about a generally horizontal tilt/trim axis, and a drive unit pivotally connected to the swivel bracket about a steering axis. The steering axis is generally perpendicular to the tilt/trim axis. A hydraulic actuator is operatively connected to the stern bracket and the swivel bracket for pivoting the swivel bracket and the drive unit relative to the stern bracket about the tilt/trim axis. A pump is mounted to the swivel bracket. The pump is pivotable about the tilt/trim axis together with the swivel bracket. The pump is fluidly connected to the hydraulic actuator to supply hydraulic fluid to the hydraulic actuator.Type: GrantFiled: October 20, 2016Date of Patent: March 27, 2018Assignee: BRP US INC.Inventors: Darrell Wiatrowski, Mark Whiteside, George Broughton, Mark Noble
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Patent number: 9595029Abstract: A checkout system includes a checkout station having a housing, a customer interface and a customer unloading station. A point-of-sale system has a microprocessor and memory operatively associated with one another to identify products being purchased, payments tendered therefor and to store transaction information locally at the checkout station or remotely from the checkout station. The microprocessor has programming configured to allow an item to be scanned by a product identification scanner, and an attendant command module.Type: GrantFiled: October 4, 2013Date of Patent: March 14, 2017Assignee: ECR Software CorporationInventors: Peter Terry Catoe, Mark Noble, John L. White, Burt Aycock, Claire McRoberts