Abstract: The present disclosure provides SPAK/OSR inhibitors. In certain embodiments, the compounds of the disclosure can be used to treat, ameliorate, and/or prevent certain cancers in a subject.

Abstract: Electrochemistry is used to generate active nitrating species from nitrate salt in situ in an aprotic solvent to eliminate acidic and/or toxic waste streams associated with the production of energetic materials. The systems/methods perform alcohol nitration without using nitric acid and/or sulfuric acid. As a result, the systems/methods may be operated under milder conditions (e.g., room temperature and ambient pressure). In addition, the disclosed systems/methods offer high product selectivity via controlling electrolysis potential. The electrochemical synthetic method is scalable, highly amenable to continuous processing and can make use of inexpensive feedstocks, making the systems/methods well-suited to large-scale manufacture.

Abstract: The disclosure provides compounds, and compositions comprising such compounds, that can be used to treat CXCR5-expressing cancers, especially angioimmunoblastic T cell lymphoma (AICL) and/or cutaneous T cell lymphoma (CTCL).

Abstract: A mount for a soundbar includes a positioning column, and a positioning mechanism operably coupled to the positioning column. The positioning column is selectively shiftable relative to the positioning mechanism. A pair of mounting arms is coupled to the positioning mechanism, the mounting arms adapted to attach to a television and a sound bar interface is operably coupled to the positioning column.

Abstract: A mount that enables a smart home device or directional speaker to be selectively positioned so as to optimize audibility.

Abstract: In one aspect, the invention provides compounds and methods that are useful for treating bacterial infections:

Abstract: The disclosure relates, in certain aspects, to the discovery of certain compounds that are useful to treat and/or prevent fungal infections in a subject. The disclosure further relates, in certain aspects, to the discovery of certain compounds that are useful are useful for treating, ameliorating, and/or preventing diseases or disorders associated with reduced and/or deficient PanK activity in a subject. In certain embodiments, the disease or disorder comprises a neurodegenerative disease, such as but not limited to pantothenate kinase-associated neurodegeneration (PKAN).

Abstract: The present disclosure provides SPAK/OSR inhibitors. In certain embodiments, the compounds of the disclosure can be used to treat, ameliorate, and/or prevent certain cancers in a subject.

Abstract: A mount for a soundbar includes a positioning column, and a positioning mechanism operably coupled to the positioning column. The positioning column is selectively shiftable relative to the positioning mechanism.

Abstract: The disclosure provides compounds, and compositions comprising such compounds, that can be used to treat CXCR5-expressing cancers, especially angioimmunoblastic T cell lymphoma (AICL) and/or cutaneous T cell lymphoma (CTCL).

Abstract: A mount that enables a smart home device or directional speaker to be selectively positioned so as to optimize audibility.

Abstract: In one aspect, the invention provides compounds and methods that are useful for treating bacterial infections:

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, to present a video. One of the methods includes receiving an indication of a line of a form of a settlement document. One of the methods includes obtaining settlement information for a user, the settlement information associated with the line of the form. One of the methods includes selecting non-personalized content, at least some of the non-personalized content selected based on the settlement information. One of the methods includes generating a user specific video using the settlement information and the selected non-personalized content. One of the methods also includes providing the user specific video to the user.