Abstract: Implementations described herein comprise systems, apparatus and methods for calibration of imaging, radio frequency or spectroscopic instruments that can be used to validate, calibrate or confirm the calibration thereof. In one aspect, a calibration target is provided. The calibration target has a tissue interface and an instrument interface. The instrument interface has a first storage means having a first set of calibration data encoded therein and a second storage means having a second set of calibration data encoded therein. The first storage means and the second storage means are selected to comprise different storage modalities. Both the first and second set of calibration data are necessary to perform calibration of the instrument.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: A heat treated electrochromic device comprising an anodic complementary counter electrode layer comprised of a mixed tungsten-nickel oxide and lithium, which provides a high transmission in the fully intercalated state and which is capable of long term stability, is disclosed. Methods of making an electrochromic device comprising an anodic complementary counter electrode comprised of a mixed tungsten-nickel oxide are also disclosed.

Abstract: Disclosed is a method for optimising an ex-vivo autologous cell culture procedure, said method including the steps of: obtaining and storing a patient's bioinformatic data; comparing said patient's bioinformatic data with known data in the form of bioinformatic data collected from other patients and/or other predetermined data such as genomic or proteomic data; and selecting ex-vivo cell culture procedure parameters based on the comparison between said patient's bioinformatic data and said known data. The selection can also be influenced by using the better data and/or culture parameter indicators determined by monitoring the outcome of plural cellular therapy attempts.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: A closed door operation racking device is provided for racking a circuit breaker to and from a power bus from outside of a housing of a motor control center unit. The racking device includes a racking operator assembly and a push-button interlock assembly. The racking operator is configured to rack-in the electrical device and connect the stabs to a power bus in a connected position and to rack-out the electrical device and disconnect the stabs from the power bus in a disconnected position. The push-button interlock assembly prevents the operation of the racking operator under certain conditions, and includes a spring-loaded locker assembly and a spring-loaded push-button operator assembly. A push-button operator of the push-button operator assembly is depressed to disengage the locker assembly from the racking operator to allow operation of the racking operator.

Abstract: A kit for attenuation of noise includes a noise source audio transducer, two ear pieces, and a control unit. The two ear pieces have respective resilient bodies that engage outer portions of ear canals of respective ears of a user while respective in-ear transducers of the two ear pieces are respectively positioned in inner portions of the ear canals. The respective in-ear transducers detect discrepancies (e.g., incomplete superpositioning) between the noise and the anti-noise. The respective in-ear transducers optionally detect respective secondary path effects in the ear canals. The noise source audio transducer detects noise generated by a noise source (e.g., snoring noise). The control unit configures an adaptive filter based at least in part on an error signal, and optionally based in part on secondary path effects. The control unit generates signals representative of anti-noise. The two ear pieces produce the anti-noise responsive to the signals.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: Data related to the adherence of a patient to a therapy regime can be collected from multiple medical devices, each of which may have an incomplete data set with data entries associated with times. Each incomplete data set represents a portion of a complete data set. The data sets can be integrated to create a complete data set with data entries from each incomplete data set being arranged in a temporal sequence with respect to one another. A report may be generated, the report having the data entries of the complete data set or a function of the data entries of the complete data set.

Abstract: A heat treated electrochromic device comprising an anodic complementary counter electrode layer comprised of a mixed tungsten-nickel oxide and lithium, which provides a high transmission in the fully intercalated state and which is capable of long term stability, is disclosed. Methods of making an electrochromic device comprising an anodic complementary counter electrode comprised of a mixed tungsten-nickel oxide are also disclosed.

Abstract: Provided are devices for determining the correct aiming point of a low velocity projectile and methods and systems for using the devices. For example, the devices can be attached to a bow and used to improve accuracy for hunting game.

Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.

Abstract: A flow generator for use in respiratory therapy can be constructed with a housing. A support fixation arrangement can be fixed to the housing. The support fixation arrangement can have a tab having an aperture that may be fitted over a hook extending from a support structure. The tab can be fixed to the housing such that it is manually liftable or pivotable about a plane.

Abstract: The present invention relates to the discovery that mutations in SCN9A are causative of Congenital Indifference to Pain (CIP) in humans. The invention also relates to methods of using compounds small organic compounds to treat pain as well as to predict the effect of analgesic agents in patients, such as those possessing gain of function mutations.

Abstract: The present invention relates to the discovery that mutations in SCN9A are causative of Congenital Indifference to Pain (CIP) in humans. The invention also relates to methods of using compounds small organic compounds to treat pain as well as to predict the effect of analgesic agents in patients, such as those possessing gain of function mutations.

Abstract: Implementations described herein comprise systems, apparatus and methods for calibration of imaging, radio frequency or spectroscopic instruments that can be used to validate, calibrate or confirm the calibration thereof. In one aspect, a calibration target is provided. The calibration target has a tissue interface and an instrument interface. The instrument interface has a first storage means having a first set of calibration data encoded therein and a second storage means having a second set of calibration data encoded therein. The first storage means and the second storage means are selected to comprise different storage modalities. Both the first and second set of calibration data are necessary to perform calibration of the instrument.

Abstract: One object of the present invention is to provide an electrochromic device having improved insulating film structure to reduce electrical leakage. The improved structure includes a lower conductive layer, upper transparent conductive layer, an electrochromic electrode layer, a counter electrode layer, and at least one ion-conductor layer sandwiched between the electrochromic electrode layer and the counter electrode layer. The lower transport conductive layer is scribed and the gap formed from the scribing is filled with the layer(s) formed above the lower conductive layer, such as the electrode layer formed directly above the lower conductive layer. The effective linewidth of the scribe is greater than the migration length of the lithium ions intercalated into the electrode layer, such that the electrode materials occupying the gap do not convert the electrode layer into an electrically conductive region.

Abstract: One object of the present invention is to provide an electrochromic device having improved insulating film structure to reduce electrical leakage. The improved structure includes a lower conductive layer, upper conductive layer, an electrochromic electrode layer, a counter electrode layer, and at least one ion-conductor layer sandwiched between the electrochromic electrode layer and the counter electrode layer. The lower conductive layer and the electrochromic electrode layer are scribed and the gap formed from the scribing is filled with the layers formed above the electrochromic electrode layer. In some aspects, the ion-conductor layer is also scribed with the lower conductor and electrochromic electrode layers and the gap formed from the scribing is filled with the layers formed above the ion-conductor layer. In further aspects, the insulating film may include one or more buffer layers formed above an ion-conductor layer, further separating the upper conductive layer from the lower conductive layer.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.