Patents by Inventor Mark Samuel
Mark Samuel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6294667Abstract: The present invention discloses a method of separating or distinguishing carbohydrate substances. More particularly the method includes using fluorescent labeling reagents which have a positive charge when bound to a carbohydrate, involves separating the labeled carbohydrate substances, such as by performing electrophoresis to cause differential migration of different labeled carbohydrate substances, or by isoelectric focusing in a pH gradient. The fluorescent labeling reagents are preferably cyanine dyes.Type: GrantFiled: June 10, 1999Date of Patent: September 25, 2001Assignee: Amersham International PLCInventors: Peter Jackson, William Jonathan Cummins, Richard West, John Anthony Smith, Mark Samuel Jonathan Briggs
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Patent number: 6230773Abstract: A tire having at least one crescent-shaped rubber composition as an insert in its sidewall region which is comprised of at least one diene-based elastomer, carbon black and, optionally, silica and at least one of dithiodipropionic acid, benzoic acid and salicylic acid.Type: GrantFiled: March 17, 1998Date of Patent: May 15, 2001Assignee: The Goodyear Tire & Rubber CompanyInventors: Paul Harry Sandstrom, Raymond Dean McQuate, Mark Samuel Sinsky
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Patent number: 6226541Abstract: A disposable calibration device is used to calibrate a measurement system which transmits radiation or acoustic waves to a material or tissue in order to effect measurements. The disposable calibration device includes a structure with a window through which the radiation or acoustic waves can be transmitted, as well as a removable calibration target arranged on the window and capable of returning a portion of the radiation or acoustic waves for calibrating the measurement system. The removable calibration target can be peeled from a window to allow a measurement to be made on the material or tissue. Once a measurement is complete, the disposable calibration device can be discarded and a new calibration device can be inserted on the measuring system.Type: GrantFiled: December 17, 1997Date of Patent: May 1, 2001Assignee: SpectRx, Inc.Inventors: Jonathan A. Eppstein, Mark A. Samuels, Keith D. Ignotz
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Patent number: 6220323Abstract: The invention relates to a rubber composition containing relatively low levels of carbon black and/or silica reinforcement together with a particulate calcium carbonate and selected modifiers. The invention particularly relates to a tire having a component, particularly a tread, of such composition.Type: GrantFiled: January 29, 1998Date of Patent: April 24, 2001Assignee: The Goodyear Tire & Rubber CompanyInventors: Paul Harry Sandstrom, Mark Samuel Sinsky
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Patent number: 6192734Abstract: A combined infection shield and calibration or reference target for use with a measuring instrument includes a removable calibration/reference layer. The removable calibration/reference layer has predetermined optical characteristics that can be utilized to calibrate or reference the instrument. When the calibration/reference layer is removed from the remaining portions of the device, the portion of the calibration/reference layer having the predetermined optical characteristics is irrevocably altered such that the calibration/reference layer cannot be reused. The combined infection shield and target may be attached to a shield holder, which in turn is attached to an instrument. Alternatively, the infection shield and target may be attached directly to an instrument. The target may include a calibration/reference layer having a reduced strength portion which causes the target to tear or separate in a predetermined manner.Type: GrantFiled: April 6, 1999Date of Patent: February 27, 2001Assignee: SpectRx, IncInventors: Robert Rothfritz, Scott Kerr, Glenn Steven Arche, Scott Kellogg, Gregory J. Newman, Mark A. Samuels, Richard Lachlan Fowler
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Patent number: 6191785Abstract: A method and system for dynamically manipulating values associated with graphical elements displayed within a graphic interface of a data-processing system. Initially a pointer element associated with a pointing device is displayed within the graphic interface, such that the pointer element is capable of movement in multiple directions in response to movement of the pointing device. A trackslide element and a moveable slider are displayed within the graphic interface. The moveable slider permits users to dynamically decrease or increase values associated with the trackslide element, such that the moveable slider is constrained to move only in a first direction along the trackslide element. The pointer element is then graphically attached to the moveable slider.Type: GrantFiled: December 2, 1997Date of Patent: February 20, 2001Assignee: International Business Machines CorporationInventors: Randal Lee Bertram, Mark Samuel Freeman
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Patent number: 6174288Abstract: A heart beat cycle indicating device for indicating to a firearm operator a defined stage of the heart beat cycle of the firearm operator includes a heart beat cycle monitoring unit for monitoring the heart beat cycle of the firearm operator and a heart beat cycle indicating unit for indicating to the firearm operator a specific stage of the heart beat cycle. A heart beat cycle override unit may be used in combination with the heart beat cycle indicating device to prevent discharge of a firearm during a specified stage of the heart beat cycle of the firearm operator. An automatic firing assembly for automatically firing a firearm when the firearm is aligned with a target comprises a target detection unit in combination with a trigger actuation unit for actuating a firearm trigger.Type: GrantFiled: August 13, 1999Date of Patent: January 16, 2001Inventor: Mark A. Samuels
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Patent number: 6172794Abstract: An electrochromic device having successive layers of electrochromic electrolyte and counter-electrode materials. The counter-electrode material comprises an oxide of a mixture including at least two of vanadium, titanium and zirconium.Type: GrantFiled: August 22, 1998Date of Patent: January 9, 2001Assignee: Pilkington plcInventor: Mark Samuel Burdis
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Patent number: 6166202Abstract: Benzophenoxazine compounds have formula (I) where X is O or NH, Y is NR.sup.1 R.sup.2 or H, R.sup.1 and R.sup.2 are alkyl or -L-A, L is a linker and A may be a reactive group by means of which the compound is linked to a biomolecule. The compounds can be used as fluorescent dyes for labelling biomolecules.Type: GrantFiled: January 15, 1999Date of Patent: December 26, 2000Assignee: Amersham Pharmacia Biotech UK LimitedInventors: Adrian Simmonds, James N Miller, Christopher John Moody, Elizabeth Swann, Mark Samuel Jonathan Briggs, Ian Edward Bruce
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Patent number: 6140494Abstract: Novel squarate dyes are described, and adducts of these dyes with biologically significant chemical species such as nucleosides or nucleotides. The adducts have useful properties for fluorescent nucleic acid sequencing methods.Type: GrantFiled: May 12, 1999Date of Patent: October 31, 2000Assignee: Amersham Pharmacia Biotech UK LimitedInventors: Alan Lewis Hamilton, Richard Martin West, William Jonathan Cummins, Mark Samuel Jonathan Briggs, Ian Edward Bruce
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Patent number: 6092554Abstract: Hoses are often reinforced with fabric to improve their performance characteristics, such as burst strength. For instance, radiator hose used in automotive applications is generally reinforced with continuous yarn. However, it is a labor-intensive process to manufacture such hoses which include fiber reinforcements. A substantial amount of material waste also generally occurs in the manufacture of such fiber-reinforced hose. By utilizing the technique of this invention, hose which has a high level of burst strength can be manufactured without including continuous yarn reinforcement.Type: GrantFiled: January 9, 1998Date of Patent: July 25, 2000Assignee: The Goodyear Tire & Rubber CompanyInventors: Kevin James Pyle, Mark Samuel Sinsky, Paul Harry Sandstrom
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Patent number: 6045502Abstract: A system and method for calibrating a measurement instrument prior to making a measurement on a material or tissue includes utilizing a removable calibration device to calibrate the instrument, then removing a target portion of the calibration device so that a measurement may be performed. The calibration device may include an index matching agent, such as a gel, that is to be interposed between the patient's skin and an output end of the measuring instrument. A method embodying the invention may include making a bilirubin concentration measurement on a skin of a patient by measuring the amplitude of light reflected from the patient's skin at first and second wavelengths indicative of a blood content of the patient's skin, and measuring the amplitude of reflected light at a third wavelength indicative of an uncorrected bilirubin concentration, then calculating a corrected bilirubin concentration based on the three measurements.Type: GrantFiled: August 1, 1997Date of Patent: April 4, 2000Assignee: SpectRx, Inc.Inventors: Jonathan A. Eppstein, Mark A. Samuels, Keith D. Ignotz, Gregory J. Newman
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Patent number: 6030399Abstract: A fluid jet blood sampling system and method for obtaining a blood sample from a mammal, utilizes a fluid jet from a disposable jet nozzle to perforate at least the epidermis of the skin and to break at least one blood vessel, thereby allowing a quantity of blood to accumulate on the skin surface of the mammal. A cowling prevents contamination of the local environment with excess fluid, blood, etc. A drying unit may be provided to remove excess fluid, blood, etc. from the skin within the cowling. A sample of blood may be transferred to a test strip, or a collection unit may be used to collect and contain a blood sample from the mammal.Type: GrantFiled: June 4, 1997Date of Patent: February 29, 2000Assignee: SpectRx, Inc.Inventors: Keith D. Ignotz, Mark A. Samuels
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Patent number: 6002482Abstract: A combined infection shield and calibration or reference target for use with a measuring instrument includes a removable calibration/reference layer. The removable calibration/reference layer has predetermined optical characteristics that can be utilized to calibrate or reference the instrument. The calibration/reference layer may have predetermined reflectance or scattering properties, a predetermined transmissivity to light, or it may have predetermined fluorescence properties. When the calibration/reference layer is removed from the remaining portions of the device, the portion of the calibration/reference layer having the predetermined optical characteristics is irrevocably altered such that the calibration/reference layer cannot be reused. The combined infection shield and target may be attached to a shield holder, which in turn is attached to an instrument. Alternatively, the infection shield and target may be attached directly to an instrument.Type: GrantFiled: July 29, 1998Date of Patent: December 14, 1999Assignee: Spectrx, Inc.Inventors: Robert Rothfritz, Scott Kerr, Glenn Steven Arche, Scott Kellogg, Gregory J. Newman, Mark A. Samuels, Richard Lachlan Fowler, Shabbir Bambot
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Patent number: 5966859Abstract: A heart beat cycle indicating device for indicating to a firearm operator a defined stage of the heart beat cycle of the firearm operator includes a heart beat cycle monitoring unit for monitoring the heart beat cycle of the firearm operator and a heart beat cycle indicating unit for indicating to the firearm operator a specific stage of the heart beat cycle. A heart beat cycle override unit may be used in combination with the heart beat cycle indicating device to prevent discharge of a firearm during a specified stage of the heart beat cycle of the firearm operator. An automatic firing assembly for automatically firing a firearm when the firearm is aligned with a target comprises a target detection unit in combination with a trigger actuation unit for actuating a firearm trigger.Type: GrantFiled: November 14, 1997Date of Patent: October 19, 1999Inventor: Mark A. Samuels
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Patent number: 5924981Abstract: A combined infection shield and calibration or reference target for use with a measuring instrument includes a removable calibration/reference layer. The removable calibration/reference layer has predetermined optical characteristics that can be utilized to calibrate or reference the instrument. When the calibration/reference layer is removed from the remaining portions of the device, the portion of the calibration/reference layer having the predetermined optical characteristics is irrevocably altered such that the calibration/reference layer cannot be reused. The combined infection shield and target may be attached to a shield holder, which in turn is attached to an instrument. Alternatively, the infection shield and target may be attached directly to an instrument. The target may include a calibration/reference layer having a reduced strength portion which causes the target to tear or separate in a predetermined manner.Type: GrantFiled: April 3, 1998Date of Patent: July 20, 1999Assignee: SpectRx, Inc.Inventors: Robert Rothfritz, Scott Kerr, Glenn Steven Arche, Scott Kellogg, Gregory J. Newman, Mark A. Samuels, Richard Lachlan Fowler
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Patent number: 5860421Abstract: A disposable calibration device is used to calibrate a measurement system which transmits radiation or acoustic waves to a material or tissue in order to effect measurements. The disposable calibration device includes a structure with a window through which the radiation or acoustic waves can be transmitted, as well as a removable calibration target arranged on the window and capable of returning a portion of the radiation or acoustic waves for calibrating the measurement system. The removable calibration target can be peeled from window to allow a measurement to be made on the material or tissue. Once a measurement is complete, the disposable calibration device can be discarded and a new calibration device can be inserted on the measuring system.Type: GrantFiled: January 17, 1996Date of Patent: January 19, 1999Assignee: SpectRx, Inc.Inventors: Jonathan A. Eppstein, Mark A. Samuels, Keith D. Ignotz
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Patent number: 5792049Abstract: A disposable calibration device is used to calibrate a spectroscopic measurement system which transmits radiation to a material or tissue in order to effect measurements such as bilirubin measurements. The disposable calibration device includes a structure with a window through which radiation can be transmitted, as well as a removable calibration target arranged on the window and capable of returning a portion of the radiation for calibrating the spectrometer system. The removable calibration target can be peeled of the window to allow a measurement to be made on the material or tissue. Once a measurement is complete, the disposable calibration device can be discarded and a new calibration device can be inserted on the spectroscopic system.Type: GrantFiled: August 6, 1997Date of Patent: August 11, 1998Assignee: SpectRx, Inc.Inventors: Jonathan A. Eppstein, Mark A. Samuels, Keith D. Ignotz, Gregory J. Newman
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Patent number: 5762850Abstract: Hoses are often reinforced with fabric to improve their performance characteristics, such as burst strength. For instance, radiator hose used in automotive applications is generally reinforced with continuous yarn. However, it is a labor-intensive process to manufacture such hoses which include fiber reinforcements. A substantial amount of material waste also generally occurs in the manufacture of such fiber-reinforced hose. By utilizing the technique of this invention, hose which has a high level of burst strength can be manufactured without including continuous yarn reinforcement.Type: GrantFiled: December 16, 1996Date of Patent: June 9, 1998Assignee: The Goodyear Tire & Rubber CompanyInventors: Kevin James Pyle, Mark Samuel Sinsky, Paul Harry Sandstrom
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Patent number: 5756589Abstract: The present invention relates to a rubber composition containing substantial silica reinforcement and pneumatic tires having treads comprised of such rubber composition. The rubber composition comprises an elastomer, substantial silica reinforcement, optionally a minor amount of carbon black reinforcement, and a triblock copolymer of terminal hard styrene based segments and of internal diene based elastomer segments.Type: GrantFiled: September 19, 1996Date of Patent: May 26, 1998Assignee: Goodyear Tire & Rubber CompanyInventors: Paul Harry Sandstrom, David John Zanzig, Mark Samuel Sinsky