Abstract: The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.

Abstract: The present invention relates to certain novel compounds of Formula (I): and methods for the treatment of prokineticin 2 or prokinetin 2 receptor mediated disorders.

Abstract: The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.

Abstract: A method of forming a carbon nanotube array on a substrate is disclosed. One embodiment of the method comprises depositing a composite catalyst layer on the substrate, oxidizing the composite catalyst layer, reducing the oxidized composite catalyst layer, and growing the array on the composite catalyst layer. The composite catalyst layer may comprise a group VIII element and a non-catalytic element deposited onto the substrate from an alloy. In another embodiment, the composite catalyst layer comprises alternating layers of iron and a lanthanide, preferably gadolinium or lanthanum. The composite catalyst layer may be reused to grow multiple carbon nanotube arrays without additional processing of the substrate. The method may comprise bulk synthesis by forming carbon nanotubes on a plurality of particulate substrates having a composite catalyst layer comprising the group VIII element and the non-catalytic element. In another embodiment, the composite catalyst layer is deposited on both sides of the substrate.

Abstract: The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 2 or prokinetin 2 receptor mediated disorders.

Abstract: A central labeling data (CLD) management system provides centralized management, assembly, and distribution of labeling data for use in generating replacement labels for damaged vehicles. For example, the CLD management system includes a database that stores label data for a plurality of vehicles produced by a plurality of different manufacturers. The CLD management system presents an interface to receive an electronic communication from a client computing device associated with a repair shop. The electronic communication includes a request for label data associated with an original vehicle label. The CLD management system retrieves the requested label data from the database and communicates the label data to an output device for printing a new vehicle label for use by the repair shop.

Abstract: The method of the present invention is directed to masking or protecting a substrate utilizing a protection sheet (10) having a contact surface containing a plurality of protrusions (14) spaced apart by a plurality valleys (12), and an opposing back surface containing a plurality of hollow portions corresponding to the protrusions (14). The valleys (12) of the contact surface of the protection sheet (10) are coated with a pressure sensitive adhesive (16), while the protrusions (14) provide spacing which prevents premature sticking of the protection sheet (10) onto the substrate. The invention is particularly suited for use in automotive repair applications.

Abstract: A microarray comprises a microstructured surface and an attachment chemistry layer disposed on at least a portion of the microstructured surface, the microstructured surface comprising primary microstructured elements comprising walls.

Abstract: The invention relates to the discovery of triazolopyrimidine derivatives of formula (I), which have been found to exhibit inhibitory activity against the serine-tyrosine and tyrosine kinases.

Abstract: A central labeling data (CLD) management system provides centralized management, assembly, and distribution of labeling data for use in generating replacement labels for damaged vehicles. For example, the CLD management system includes a database that stores label data for a plurality of vehicles produced by a plurality of different manufacturers. The CLD management system presents an interface to receive an electronic communication from a client computing device associated with a repair shop. The electronic communication includes a request for label data associated with an original vehicle label. The CLD management system retrieves the requested label data from the database and communicates the label data to an output device for printing a new vehicle label for use by the repair shop.

Abstract: The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.

Abstract: A portable device, such as a pedometer or other device having a display portion that may be separated from an attachment portion for easier viewing. When separated, the display portion remains connected to the attachment portion to facilitate ease of re-attachment and for maintaining both parts of the device in an interconnected relationship. The attachment portion is removably connectable to a wearer. The display portion is extendably and retractably connected to the attachment module. A spring biased spool is provided in the attachment module to take up and release line connecting the display module to the attachment module. The display module has a receptacle formed on the back thereof. The attachment module has a protrusion extending from a back thereof for mating engagement with the receptacle when the display module and attachment module are in a retracted position.

Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.

Abstract: A portable device, such as a pedometer or other device having a display portion that may be separated from an attachment portion for easier viewing. When separated, the display portion remains connected to the attachment portion to facilitate ease of re-attachment and for maintaining both parts of the device in an interconnected relationship. The attachment portion is removably connectable to a wearer. The display portion is extendably and retractably connected to the attachment module. A spring biased spool is provided in the attachment module to take up and release line connecting the display module to the attachment module. The display module has a receptacle formed on the back thereof. The attachment module has a protrusion extending from a back thereof for mating engagement with the receptacle when the display module and attachment module are in a retracted position.

Abstract: The invention is directed to compounds and methods of synthesizing hydroxyethlamino amides and their use in treatment of aspartyl protease mediated diseases and conditions.

Abstract: This invention is directed to 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives useful as ?-opioid or ?-opioid receptor modulators. Depending on their agonist or antagonist effect, the compounds are useful analgesics, immunosuppressants, antiinflammatory agents, agents for the treatment of neurological and psychiatric conditions, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents and agents for the treatment of respiratory diseases.

Abstract: A system designed to drill multiple rows of holes utilizing a simplified belt drive. The basic embodiment of the apparatus comprises of a platform on which several drilling heads are affixed independently on twin axes. The multiple rows of drill bits are arranged in such a way as to allow the top segment of each bit to revolve as well as articulate in a direction at a tangent to the circular drilling motion facilitating the drill into the substrate. The bits are each independent and derive the motion necessary for rotation and reciprocating motion through the interaction of a special belt designed to impart rotary and linear motion. In its most basic embodiment the drill platform is controlled and powered by a single belt drive. The system is able to create twin rows of holes using a simple rotating power source to drive the belt that creates both rotary and linear motion to each of the drill heads.