Abstract: An inkjet printer has a print assembly and a print material feed system comprising a first circulation circuit and a second circulation circuit, the first circulation circuit fluidly coupled between the second circulation circuit and the print assembly.

Abstract: Described herein are compositions and methods for the delivery of microbial therapeutics useful for the treatment of disorders related to intestinal dysbiosis.

Abstract: An inductive sensor device includes at least one die mounted in or on a substrate, a redistribution layer (RDL) region formed over the at least one die and including multiple RDL metal layers, and at least one inductive coil formed in the RDL region and including at least one conductive coil element formed in at least one RDL metal layer of the multiple RDL metal layers, wherein the at least one die includes sensor circuitry connected to the at least one inductive coil to perform sensor measurements.

Abstract: A bound collection of leaves having a spine and a method of its manufacture are disclosed. Each leaf of a first plurality of leaves of the bound collection includes a first pattern of tabs by which that leaf is bound. The tabs of the first pattern are distributed along a binding axis of that leaf that is parallel to a spine axis of the spine. Each leaf of a second plurality of leaves of the bound collection includes a second pattern of tabs different than the first pattern by which that leaf is bound. The tabs of the second pattern are distributed along a binding axis of that leaf that is parallel to the spine axis. Each tab of the first pattern and second pattern of tabs extends in a direction orthogonal to the binding axis from within an unbound region to a binding-side edge of that leaf.

Abstract: Systems and computer-implemented methods of generating recipient-facilitated blockchain transactions. A recipient device transmits a recipient outpoint to a sender device. The sender device returns a partially-complete transaction containing the recipient outpoint as a recipient input to the partially-complete transaction and containing at least one sender input.

Abstract: Compounds, compositions and methods are provided for the inhibition of ENPP1. Aspects of the subject methods include contacting a sample with an ENPP1 inhibitor compound to inhibit the cGAMP hydrolysis activity of ENPP1. In some cases, the ENPP1 inhibitor compound is cell impermeable. ENPP1 inhibitor compounds can act extracellularly to block the degradation of cGAMP. Also provided are pharmaceutical compositions and methods for treating cancer. Aspects of the methods include administering to a subject a therapeutically effective amount of an ENPP1 inhibitor to treat the subject for cancer. In certain cases, the cancer is a solid tumor cancer. Also provided are methods of administering radiation therapy to a subject in conjunction with administering an ENPP1 inhibitor to the subject. The radiation therapy can be administered in the subject methods at a dosage and/or frequency effective to reduce radiation damage to the subject, but still instigate an immune response.

Abstract: The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

Abstract: An inkjet printer has a print assembly and a print material feed system comprising a first circulation circuit and a second circulation circuit, the first circulation circuit fluidly coupled between the second circulation circuit and the print assembly.

Abstract: Techniques are provided for implementing a file system format for persistent memory. A node, comprising persistent memory, receives an operation comprising a file identifier and file system instance information. A list of file system info objects are evaluated to identify a file system info object matching the file system instance information. An inofile, identified by the file system info object as being associated with inodes of files within an instance of the file system targeted by the operation, is traversed to identify an inode matching the file identifier. If the inode comprises an indicator that the file is tiered into the persistent memory, then the inode it utilized to facilitate execution of the operation upon the persistent memory. Otherwise, the operation is routed to a storage file system tier for execution by a storage file system upon storage associated with the node.

Abstract: Microsphere formulations comprising asenapine are provided. Methods for making and using the microsphere formulations are also provided.

Abstract: Techniques are provided for implementing a persistent memory storage tier to manage persistent memory of a node. The persistent memory is managed by the persistent memory storage tier at a higher level within a storage operating system storage stack than a level at which a storage file system of the node is managed. The persistent memory storage tier intercepts an operation targeting the storage file system. The persistent memory storage tier retargets the operation from targeting the storage file system to targeting the persistent memory. The operation is transmitted to the persistent memory.

Abstract: A CPU includes a processor die and a substrate. The processor die includes first signal contacts, power contacts, and ground contacts. The processor die is affixed and electrically coupled to the substrate on a first surface of the substrate. The substrate routes the first signal contacts to associated second signal contacts on a second surface of the substrate. The substrate further routes a subset of the power contacts to a power pad on the first surface of the substrate, and routes a subset of the ground contacts to a ground pad on the first surface of the substrate.

Abstract: A genus of compounds encompassed by formula (III) and their use is disclosed: The compounds activate Ppargc1a and, as a consequence, are useful for treating a variety of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, Huntington's disease, frontotemporal degeneration, dementia with Lewy bodies, motor neuron diseases, and a demyelinating disease.

Abstract: A method for communicating information related to a diagnostic analyzer includes receiving user identification information from a portable computer. A user associated with the user identification information operates the diagnostic analyzer. First diagnostic analyzer information is retrieved from at least one database that relates analyzer information to the user of the diagnostic analyzer. The first diagnostic analyzer information is related to the diagnostic analyzer. The first diagnostic analyzer information is communicated to the portable computer. Second diagnostic analyzer information from the diagnostic analyzer is retrieved. The second diagnostic analyzer information is generated by the diagnostic analyzer. The first and the second diagnostic analyzer information is communicated to the portable computer. The portable computer is configured to display the first and the second diagnostic analyzer related information.

Abstract: Presented herein are techniques to control the spread of current beyond, in an apical direction, a predetermined location/point in the cochlea. As a result, the techniques presented herein create a protected apical zone at an apical side of the predetermined location for undisturbed acoustic temporal coding (i.e., an apical region of the cochlea in which the voltage fields from delivered current signals are nulled, minimized, or otherwise controlled in order to eliminate, reduce, or otherwise limit electro-acoustic interactions that could negatively affect remaining low-frequency hair cells).

Abstract: An information handling system includes a PCB, a CPU, a power distribution hat, and a heat sink. The PCB includes a first power contact on a first surface of the PCB and a first ground contact on a second surface of the PCB. The CPU includes a substrate and is affixed and electrically coupled to the first surface of the PCB by a first surface of the substrate. A second surface of the substrate includes a second power contact and a second ground contact. The power distribution hat couples the first power contact with the second power contact. The heat sink couples the first ground contact with the second ground contact.

Abstract: An information handling system includes a PCB, a CPU, a power distribution hat, and a heat sink. The PCB includes a first power contact on a first surface of the PCB and a first ground contact on a second surface of the PCB. The CPU includes a substrate and is affixed and electrically coupled to the first surface of the PCB by a first surface of the substrate. A second surface of the substrate includes a second power contact and a second ground contact. The power distribution hat couples the first power contact with the second power contact. The heat sink couples the first ground contact with the second ground contact.

Abstract: A utility vehicle includes a wheeled chassis and a side-dump bed. The wheeled chassis includes a chassis frame extending along a fore-and-aft vehicle axis. The side-dump bed is configured to contain and selectively discharge material toward a dump side of the wheeled chassis. The side-dump bed is shiftably attached to the chassis frame for movement between a lowered condition, in which the side-dump bed extends laterally from the dump side of the wheeled chassis to the other side, and a raised condition, in which the side-dump bed is shifted toward the dump side to discharge material.

Abstract: Closure (1), for sealing of a neck finish (2) of a liquid container, comprising a top deck (3) and an outer skirt (4) extending from the top deck (3) in an axial direction (z) away from the top deck (3). The outer skirt (4) comprises a top section (5) arranged adjacent to the top deck (2) and a bottom section (6) separated from the top section (5) by a gap (7). The top section (5) and the bottom section (6) are interconnected to each other by a hinge (8). The outer skirt (4) comprises an inwardly protruding locking bead (9) extending along an inner surface (10) of the outer skirt (4), wherein the locking bead (9) at at least one location continues across the gap (7).

Abstract: An apparatus comprises a target to rotate about an axis; an excitation coil to carry an excitation signal; and a first sense coil to carry a sense signal induced by the excitation signal. The first sense coil comprises two or more lobes in one or more planes that are perpendicular to the axis. The two or more lobes comprise a first lobe at a first position relative to the axis and a second lobe at a second position relative to the axis. The second position is substantially the same radial distance from the axis as the first position is from the axis. The second position is at an angular distance of ? from the first position, where ?=180°±?/2, and ? is a measurement range for angular-position sensing (e.g., ?=60°) within a range of 50% to 150% of ?.