Patents by Inventor Mark T. Reed

Mark T. Reed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6451261
    Abstract: The present invention provides multi-well plates and column arrays in which samples (e.g., cell lysates containing nucleic acids of interest, such as RNA) can be analyzed and/or processed. In one embodiment, the microfiltration arrangement is a multilayer structure, including (i) a column plate having an array of minicolumns into which samples can be placed, (ii) a discrete filter element disposed in each minicolumn, (iii) a drip-director plate having a corresponding array of drip directors through which filtrate may egress, and (iv) a receiving-well plate having a corresponding array of receiving wells into which filtrate can flow. The invention provides multi-well microfiltration arrangements that are relatively simple to manufacture and that overcome many of the problems associated with the prior arrangements relating to (i) cross-contamination due to wicking across a common filter sheet or (ii) individual filter elements entrapping sample constituents within substantial dead volumes.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: September 17, 2002
    Assignee: Applera Corporation
    Inventors: Kevin S. Bodner, Alfred P. Madden, Joseph Jackson, Jason H. Halsey, Mark T. Reed, Ward Frye, Mark F. Oldham, Stephen E. Moring, Jon Hoshizaki
  • Patent number: 6338802
    Abstract: The present invention provides multi-well plates and column arrays in which samples (e.g., cell lysates containing nucleic acids of interest, such as RNA) can be analyzed and/or processed. In one embodiment, the microfiltration arrangement is a multilayer structure, including (i) a column plate having an array of minicolumns into which samples can be placed, (ii) a discrete filter element disposed in each minicolumn, (iii) a drip-director plate having a corresponding array of drip directors through which filtrate may egress, and (iv) a receiving-well plate having a corresponding array of receiving wells into which filtrate can flow. The invention provides multi-well microfiltration arrangements that are relatively simple to manufacture and that overcome many of the problems associated with the prior arrangements relating to (i) cross-contamination due to wicking across a common filter sheet or (ii) individual filter elements entrapping sample constituents within substantial dead volumes.
    Type: Grant
    Filed: May 4, 2000
    Date of Patent: January 15, 2002
    Assignee: PE Corporation (NY)
    Inventors: Kevin S. Bodner, Alfred P. Madden, Joseph Jackson, Jason H. Halsey, Mark T. Reed, Ward Frye, Mark F. Oldham, Stephen E. Moring, Jon Hoshizaki
  • Patent number: 6159368
    Abstract: The present invention provides multi-well plates and column arrays in which samples (e.g., cell lysates containing nucleic acids of interest, such as RNA) can be analyzed and/or processed. In one embodiment, the microfiltration arrangement is a multilayer structure, including (i) a column plate having an array of minicolumns into which samples can be placed, (ii) a discrete filter element disposed in each minicolumn, (iii) a drip-director plate having a corresponding array of drip directors through which filtrate may egress, and (iv) a receiving-well plate having a corresponding array of receiving wells into which filtrate can flow. The invention provides multi-well microfiltration arrangements that are relatively simple to manufacture and that overcome many of the problems associated with is the prior arrangements relating to (i) cross-contamination due to wicking across a common filter sheet or (ii) individual filter elements entrapping sample constituents within substantial dead volumes.
    Type: Grant
    Filed: October 29, 1998
    Date of Patent: December 12, 2000
    Assignee: The Perkin-Elmer Corporation
    Inventors: Stephen E. Moring, Kevin S. Bodner, Jason H. Halsey, Jon Hoshizaki, Joseph Jackson, Alfred P. Madden, Mark F. Oldham, Mark T. Reed