Abstract: The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of an acute coronary syndrome in a blood sample from a human. Further, the present invention relates to means for diagnosing and/or prognosing of an acute coronary syndrome comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of an acute coronary syndrome based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome compared to a reference. In addition, the present invention relates to a kit for diagnosing and/or prognosing of an acute coronary syndrome comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome and at least one reference.

Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.

Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.

Abstract: MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.

Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.

Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miR-NAs that have altered expression levels in disease states compared to healthy controls.

Abstract: The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls.

Abstract: The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls.

Abstract: The invention relates to a method for acquisition of genetic information, in particular for personalized medicine.

Abstract: The invention relates to a method for isolation of target molecules from a nucleic acid population.

Abstract: The invention relates to improved molecular-biological processing equipment and an improved method of processing biological samples. The invention combines the provision of biologically functional molecules such as nucleic acids and peptides and of derivatives or analogs of these two classes of molecules in miniaturized flow cells with the sequential addition of reagents or fluids and serves for the processing of biological samples, such as proteins, nucleic acids, biogenic small molecules such as e.g. metabolites, viruses or cells, which for this purpose are introduced into the miniaturized flow cells.

Abstract: The invention relates to an extraction method for isolating target molecules from a sample with the help of a molecule library.

Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.

Abstract: The invention relates to a template-based method for preparing nucleic acid double strands.

Abstract: The invention relates to a process and a device for the determination of the transfer of a sample substance in the production of biopolymer fields or biopolymer arrays onto the surface (4) of a specimen slide (3). The surface (4) of a specimen slide (3) comprises a conductive material (14) whose electrical connection to the feed device (1) via the sample liquid (12) serves as acknowledgement signal (8).

Abstract: The invention relates to a method for the determination of analytes using carrier chips comprising arrays of different receptors in immobilized form on the surface of said chips. The method is performed dynamically in several cycles. Information obtained in a previous cycle on the modification or alteration of said receptors is used in the following cycle.

Abstract: The invention relates to a method of increasing the sensitivity and specificity of nucleic acid chip hybridization tests and to devices suitable for carrying out the inventive method.

Abstract: The present invention relates to a process for derivatizing supports on a carriers, wherein a functional group is activated on a support surface by reaction with an activating reagent and then reacted with an amine component. The invention also relates to a support with a dendrimer structure on its surface and to the use of a support that has been produced according to the invention for binding biopolymers.

Abstract: The invention relates to a method and an apparatus for determining analytes by electronic detection using a microfluidic support.

Abstract: The invention relates to a method and a device for the production of a carrier, in particular a microfluidic carrier, for determining analytes.