Abstract: Two parts are joined along a joining gap disposed therebetween by welding by illuminating the joining gap with an energy beam through a mobile vacuum chamber which is moved, on the side to be welded, on the parts being joined along the joining gap and in which a vacuum is generated. The vacuum chamber forms a first vacuum chamber in which, during welding, a vacuum having a first pressure level is generated, and a vacuum having a second pressure level is generated in a second vacuum chamber which adjoins the first vacuum chamber directly at a chamber wall thereof and which, during welding, regionally covers the joining gap. The pressure levels in the two vacuum chambers are matched to one another or the first pressure level is raised to above the second pressure level by way of a pressure regulating system.

Abstract: The present invention relates to a method for treating cancer in a subject, comprising the step of administering to a subject in need thereof administering a therapeutically effective dose of a T cell capable of binding a neopeptide that is expressed by a tumor suppressor gene, wherein said neopeptide is derived from a frameshift product of a tumor suppressor gene and wherein the T cell binds to the neopeptide-MHC complex with a half-life (T1/2) of at least 50 s.

Abstract: The present invention relates to a method for providing a neopeptide-specific T cell, wherein the neopeptide-specific T cell forms a complex having a half-life (T½) of at least 50 s with a neopeptide-MHC monomer. The present invention further relates to a T cell obtainable by the method as well as a pharmaceutical composition comprising such T cells.

Abstract: The present invention relates to inhibitors of the interaction between H. pylori HopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.

Abstract: The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.

Abstract: A mobile testing system for optimizing wireless coverage in a distributed antenna system is disclosed. In some aspects, the mobile testing system includes a measurement receiver that can determine signal levels for a respective signals communicated via the distributed antenna system. A processing device of the mobile testing system can identify a subset of the signals by decoding a respective identifier encoded in each of the subset of signals. The identifiers specify that the subset of signals is targeted to at least one coverage zone in which the mobile testing system is located. A subset of signal levels is obtained by the measurement receiver that corresponds to each of the subset of signals. The processing device can generate coverage contour data based on the subset of signal levels that describes signal coverage for at least one coverage zone.

Abstract: The present invention relates to inhibitors of the interaction between H. pylori IIopQ and a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family as well as to immunogenic compositions based on H. pylori HopQ. The present invention further relates to the use of the inhibitors and immunogenic compositions for preventing or treating a disease or disorder caused by or associated with H. pylori.

Abstract: The present invention relates to immunogenic compositions and their use in the prevention or treatment of diseases or disorders caused by or associated with Helicobacter pylori, in particular H. pylori infection and gastroduodenal disorders caused by H. pylori. The present invention further relates to methods of detecting H. pylori infection in a subject.

Abstract: The present invention relates to immunogenic compositions and their use in the prevention or treatment of diseases or disorders caused by or associated with Helicobacter pylori, in particular H. pylori infection and gastroduodenal disorders caused by H. pylori. The present invention further relates to methods of detecting H. pylori infection in a subject.

Abstract: The present invention is related to a method for detecting H. pylori infection in a subject, wherein the method comprises detecting in a sample from the subject an immune response against FliD, wherein the immune response comprises an anti-FliD antibody.

Abstract: The present invention relates to a method for providing a neopeptide-specific T cell, wherein the neopeptide-specific T cell forms a complex having a half-life (T½) of at least 50 s with a neopeptide-MHC monomer. The present invention further relates to a T cell obtainable by the method as well as a pharmaceutical composition comprising such T cells.

Abstract: The present invention is related to a polypeptide comprising an amino acid sequence, whereby the amino acid sequence of the polypeptide is at least 80% identical to a stretch of consecutive amino acids of the region of HPGGT comprising an amino acid sequence corresponding to SEQ.ID.No. 1, whereby such region is defined by (a) amino acid positions 150 to 200 of the amino acid sequence according to SEQ.ID.No.1, or (b) amino acid positions 410 to 480 of the amino acid sequence according to SEQ.ID.No.1, and whereby the polypeptide is suitable to elicit an immune response which is capable of inhibiting the catalytic activity of HPGGT.

Abstract: The present invention is related to a method for detecting H. pylori infection in a subject, wherein the method comprises detecting in a sample from the subject an immune response against FliD, wherein the immune response comprises an anti-FliD antibody.

Abstract: A lighting device for a motor vehicle headlamp is described. The device includes a reflector for focusing light emitted by a light source. At the rear end of the reflector is an opening to receive at least a part of the light source, and a reflector neck that surrounds the opening and to which the light source is fastened in a defined position relative to a reflective surface of the reflector. A plurality of locking members are formed on the reflector which in the course of a rotary movement of the light source about the optical axis of the reflector or about an axis parallel thereto when the light source has been at least partly inserted in the reflector neck, engage in corresponding perforations formed in the fight source.

Abstract: The present invention is related to a polypeptide comprising an amino acid sequence, whereby the amino acid sequence of the polypeptide is at least 80% identical to a stretch of consecutive amino acids of the region of HPGGT comprising an amino acid sequence corresponding to SEQ.ID.No. 1, whereby such region is defined by (a) amino acid positions 150 to 200 of the amino acid sequence according to SEQ.ID.No. 1, or (b) amino acid positions 410 to 480 of the amino acid sequence according to SEQ.ID.No. 1, and whereby the polypeptide is suitable to elicit an immune response which is capable of inhibiting the catalytic activity of HPGGT.

Abstract: The present invention is related to a polypeptide comprising an amino acid sequence, whereby the amino acid sequence of the polypeptide is at least 80% identical to a stretch of consecutive amino acids of the region of HPGGT comprising an amino acid sequence corresponding to SEQ. ID. No. 1, whereby such region is defined by (a) amino acid positions 150 to 200 of the amino acid sequence according to SEQ. ID. No. 1, or (b) amino acid positions 410 to 480 of the amino acid sequence according to SEQ. ID. No. 1, and whereby the polypeptide is suitable to elicit an immune response which is capable of inhibiting the catalytic activity of HPGGT.

Abstract: A high pressure discharge lamp (10), which is particularly a motor vehicle headlight, comprises a high pressure discharge burner (12) for emitting light supported by at least one leg (24), preferably three or four legs (24). By means of the legs (24) the burner (12) is mechanically connected to a socket (14) of the high pressure discharge lamp (10). According to the invention the legs (24) are part of a holder (16), which comprises further a ring (18) surrounding the socket (14), whereby the ring (18) is one-piece with the legs (24). Due to the design of the holder (16) as ring (18) with protruding legs (24) the heat of the burner (12) is conducted from the burner (12) via the legs (24) to the ring (18) by heat conduction. From the ring (18) the heat is led away to the environment by convection. This leads to a significant cooler Temperature of the holder (16) with respect to the burner (12), so that the material of the socket (14) needs not to be selected with respect to a good heat resistance.

Abstract: A mobile testing system for optimizing wireless coverage in a distributed antenna system is disclosed. In some aspects, the mobile testing system includes a measurement receiver that can determine signal levels for a respective signals communicated via the distributed antenna system. A processing device of the mobile testing system can identify a subset of the signals by decoding a respective identifier encoded in each of the subset of signals. The identifiers specify that the subset of signals is targeted to at least one coverage zone in which the mobile testing system is located. A subset of signal levels is obtained by the measurement receiver that corresponds to each of the subset of signals. The processing device can generate coverage contour data based on the subset of signal levels that describes signal coverage for at least one coverage zone.

Abstract: A method for selective deposition of Si or SiGe on a Si or SiGe surface exploits differences in physico-chemical surface behavior according to a difference in doping of first and second surface regions. By providing at least one first surface region with a Boron doping of a suitable concentration range and exposing the substrate surface to a cleaning and passivating ambient atmosphere in a prebake step at a temperature lower or equal than 800° C., a subsequent deposition step of Si or SiGe will not lead to a layer deposition in the first surface region. This effect is used for selective deposition of Si or SiGe in the second surface region, which is not doped with Boron in the suitable concentration range, or doped with another dopant, or not doped. Several devices are, thus, provided. The method thus saves a usual photolithography sequence required for selective deposition of Si or SiGe in the second surface region according to the prior art.

Abstract: It is provided a burner for automotive lamps, particularly HID lamps, comprising a discharge vessel for generating light by means of a discharge arc. A glass body for protecting the discharge vessel comprises a shaft for being inserted into a socket. The shaft comprises at least one insulation pocket for receiving a rib of the socket and for insulating the first electrode outside the glass body. Due to the insulation pocket the glass body may provide an umbrella-like dielectric increasing the minimum necessary way for a high voltage discharge arc to the uncovered part of the first electrode at the proximal end of the shaft. Due to the improved insulation effect by means of the insulation pocket, the height of the shaft of the glass body may be significantly reduced leading to a reduced height of the burner without impairing the insulation of the burner.