Abstract: A casting mold for producing a casting having a front side and a rear side from a curable casting compound, including at least a first mold part shaping the front side and a second mold part shaping the rear side, the mold parts together delimiting a casting cavity. A slide device, provided on one of the mold parts, includes a slide portion that can be driven into the casting cavity and on which a detachable insert part is or can be arranged. The insert part is able to be moved abutting against the opposite mold part and is able to be embedded into the curing casting compound, and is detached from the slide portion when the latter is moved back.

Abstract: Oral thin film comprising adrenaline or a pharmaceutically acceptable salt thereof and at least one polymer, characterized in that the water activity of the oral thin film is less than 0.6. Method for preparing said oral thin film, comprising the steps of a) preparing a solution, dispersion or melt comprising adrenaline or a pharmaceutically acceptable salt thereof and at least one polymer and b) spreading the solution, dispersion or melt from step a) or the optionally foamed solution, dispersion or melt from step a1) in order to obtain an oral thin film, and (c) drying the oral thin film obtained in step (b) in order to obtain an oral thin film having a water activity of less than 0.6. Said oral thin film for use as a medicament, particularly for use as a medicament in the treatment of allergic reactions.

Abstract: Oral thin film comprising one or more layer(s), wherein at least one layer contains adrenaline or a pharmaceutically acceptable salt thereof and at least one polymer, characterized in that the adrenaline is substantially undissolved in the at least one polymer. Method for preparing said oral thin film, comprising the steps: a) Preparing a solution comprising said at least one polymer and a solvent in which adrenaline or the pharmaceutically acceptable salt thereof is substantially insoluble, (b) addition of adrenaline, (c) spreading and drying the suspension obtained in step (b), in order to obtain a single-layer oral thin film, and Said oral thin film for use as a medicament, for use as a medicament in the treatment of allergic reactions.

Abstract: A device for mechanical overload protection in a drive train of a machine tool, the drive train having an output side with an output shaft and an input side with a motor shaft. The output shaft is operatively connected to the motor shaft by way of a connector, the device for mechanical overload protection being formed by a press-fit connection between the connector-on the one side and the motor shaft or the output shaft on the other side. A method for producing such a device for mechanical overload protection in a machine tool is also provided. The peak torques in the drive train, which preferably occur for a short time, can be significantly reduced and the machine tool and its mechanical components can be protected from damage in the event of a blockage.

Abstract: A plasma torch head, for interior coatings of rotationally symmetrical, asymmetrical, or freeform surfaces in concave or convex-shaped cavities with a distance between the surfaces to be coated greater than 40 mm using a plasma spraying process, includes a cathode whose tip has a surface roughness of less than Ra 0.2 ?m and grooves running in the axial direction of the cathode, which is secured the cathode holder Gas tightness with respect to the plasma gas is ensured by high-temperature resistant O-rings, one O-ring preventing gas leakage between the cathode holder and insulation ring, and another preventing gas leakage between the insulation ring and anode. In the cathode holder, the outflow velocity of the plasma gas in holes above the center of the cathode is lower than below the center. A plasma torch head reduces voltage fluctuations over the entire operational life of the torch head and extends its service life.

Abstract: The present invention relates to a method for producing a water-erodible, water-soluble or water-dispersible active-ingredient-administering form, in which, firstly, a film suitable as an oral film-administering form is produced which contains the active ingredient and in which a surface of the film is activated in a subsequent step in order to generate a tacky surface, followed by rolling up the activated film to form a rolled-up laminate. The present invention also relates to rolled-up laminates produced according to this method. Corresponding laminates are very stable, such that they can be dispensed and cut, and are suitable on account of their area density, which is very high by comparison with conventional OTF products, for administering active ingredients which have to be given in larger amounts.

Abstract: A casting mold for producing a casting having a front and a rear side from a curable casting compound, having at least one first mold part with a front mold face that shapes the front side and a second mold part with a rear mold face that shapes the rear side, which mold parts conjointly delimit a casting cavity. Provided on the rear mold face is a first fastening interface and provided on an insert part, by way of which a through hole on the casting is to be formed, is a second fastening interface. The insert part in the case of a closed mold bears on the rear mold face as well as on the front mold face. The two fastening interfaces are releasably connectable to one another in such a manner that, when removing the second mold part from the cured casting, the first fastening interface is automatically released from the second fastening interface.

Abstract: The invention relates to an oral thin film comprising a matrix layer containing at least one polymer, wherein a microneedle system is applied to at least one surface of the oral thin film, a method for preparing such an oral thin film, a composite comprising such a thin film and an application aid, which comprises at least one polymer, for the oral thin film, wherein the oral thin film and the application aid are firmly joined to one another, a method for preparing the oral thin film, a method for preparing the composite, and the oral thin film and the composite for use as a medicinal product.

Abstract: The invention relates to a composite comprising an oral thin film and an application aid for said oral thin film, wherein the oral thin film and the application aid are firmly joined to each other, a method for its preparation, and the composite for use as a medicinal product.

Abstract: The present invention relates to an oral thin film comprising at least one polymer and at least one pharmaceutically active agent, wherein the concentration of the at least one pharmaceutically active agent in the oral thin film is greater than the saturation concentration of the at least one pharmaceutically active agent in the oral thin film, and wherein the oral thin film comprises at least one material which serves as crystal nucleus for the at least one pharmaceutically active agent, to a method for producing said oral thin film, and to the use of said oral thin film as a medicament.

Abstract: The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin phenylethylbiguanidin, betaine-methylester and dimethylaminoethanol. The cation is an organic compound with a complementary pharmacological activity.

Abstract: A device for mechanical overload protection in a drive train of a machine tool, the drive train having an output side with an output shaft and an input side with a motor shaft. The output shaft is operatively connected to the motor shaft by way of a connector, the device for mechanical overload protection being formed by a press-fit connection between the connector-on the one side and the motor shaft or the output shaft on the other side. A method for producing such a device for mechanical overload protection in a machine tool is also provided. The peak torques in the drive train, which preferably occur for a short time, can be significantly reduced and the machine tool and its mechanical components can be protected from damage in the event of a blockage.

Abstract: Technologies and techniques for a modular instrument panel assembly for vehicle interiors, featuring enhanced mounting and update mechanisms. The assembly includes an outer instrument panel, a support bracket with vertical and horizontal sections, and a mounting bracket for secure attachment to the vehicle's dashboard. The support bracket incorporates multiple attachment points, reinforced ribs, and flanges for structural integrity. Spring-loaded alignment guides and locking mechanisms ensure precise alignment and secure attachment. The modular design allows for easy installation, removal, and customization of electronic and mechanical components.

Abstract: The present invention relates to an oral thin film comprising at least one cellulose derivative and at least one pharmaceutically active agent, the at least one pharmaceutically active agent having a water solubility of at most 50 g/L at 20° C. and a pH of 6 to 7 and being contained in the oral thin film in an amount of at least 20 wt. % in relation to the total weight of the oral thin film, and to a method for production of said oral thin film, and use thereof as a medicament.

Abstract: An example operation may include one or more of executing a first processing element among a sequence of processing elements within a data processing pipeline on input data to generate a first output, transferring the first output and context associated with the first processing element from the first processing element to a second processing element among the sequence of processing elements, within the data processing pipeline, executing the second processing element on the first output and the context to generate a second output, and storing the second output in memory.

Abstract: An example operation may include one or more of executing a first processing element among a sequence of processing elements within a data processing pipeline on input data to generate a first output, transferring the first output and context associated with the first processing element from the first processing element to a second processing element among the sequence of processing elements, within the data processing pipeline, executing the second processing element on the first output and the context to generate a second output, and storing the second output in memory.

Abstract: A device, system, or method for changing the center of gravity of a bicycle, in particular an electric bicycle, to suit the situation, with: an actuator for changing the center of gravity of the bicycle, at least one sensor that monitors the riding status of the bicycle, a control unit which receives and processes data from the sensor, determines a center of gravity of the bicycle adapted to the situation and outputs corresponding control signals to the actuator in order to carry out the change in center of gravity. According to the invention, an adjustment speed of the change in the center of gravity can be adapted to a riding state of the bicycle.

Abstract: The invention relates to a damping apparatus (10) comprising a hollow housing (19) containing a damping fluid, wherein the housing (19) comprises an opening (21), a rod (13) partially inserted through the opening (21) into the hollow housing (19), wherein the rod (13) is guided slidably along a stroke axis (A) relative to the hollow housing (19), and a piston package (16) fixed to an end of the rod (13) residing within the hollow housing (19), wherein the piston package (16) separates an upper chamber (191) of the hollow housing (19) adjacent to the opening (21) from a lower chamber (192) of the hollow housing (19). The rod (13) comprises an inner volume (131) containing a compensation fluid, wherein the inner volume (131) is connected to the lower chamber (192) in a manner conducting the damping fluid. The invention further relates to a solar panel array comprising multiple solar panels and a damping apparatus (10) according to the invention.

Abstract: An apparatus for dispensing a mixture of a diluent and an additive for sanitation, cosmetic or cleaning applications. The apparatus includes a mixing unit for creating a mixture of the diluent and the additive, a diluent supply supplying the diluent to the mixing unit, an additive supply supplying the additive to the mixing unit, an outlet for dispensing the mixture. The diluent supply includes a pump arranged to increase the pressure of the diluent before the diluent enters the mixing unit.

Abstract: The invention relates to crystalline folate salts. The salt consists of a folate anion and an organic cation. The folate anion is 5-methyl-(6S)-tetrahydrofolic acid, and the cation is an organic compound which is an alkanolamine selected from the group consisting of choline, N-methylaminoethanol, 2-amino-2-methylpropanol and 2-dimethylaminoethanol.