Abstract: This invention relates to compounds of the formula wherein one of R6, R7 or R8 is and all enantiomers and pharmaceutically acceptable salts and/or esters thereof as well as pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.

Abstract: A system and method for servicing user accounts are disclosed. The system includes one or more blades for servicing the user accounts, where each blade includes software components and hardware components, and each blade serves a group of user accounts, a blade manager for managing states of the one or more blades, and logic for incrementally adding one or more new blades in response to increase in the number of new user accounts.

Abstract: Apparatus and method for conducting secured communications with a client device in a network are disclosed. The method includes receiving at the server a request message from the client device, wherein the request message comprises a nonce, a nonce count and an encrypted request, determining whether the client device has permission to access the server using the nonce and the nonce count, forming an encrypted server response message in response to the encrypted request and the client device has permission to access the server, and issuing the encrypted server response message from the server to the client device.

Abstract: A system and method for servicing user accounts are disclosed. The system includes one or more blades for servicing the user accounts, where each blade includes software components and hardware components, and each blade serves a group of user accounts, a blade manager for managing states of the one or more blades, logic for detecting a failed blade among the one or more blades, and logic for recovering the failed blade using the states of the one or more blades managed by the blade manager.

Abstract: A system and method for sharing data between two users on different blades in scalable software blade architecture are disclosed. The system includes a plurality of blades, where each blade includes software components and hardware components, each blade serves a predefined group of users, and each user is associated with one or more user devices. The system further includes a first blade and a second blade, where the first blade connects a first user to a first connected dataset and the second blade connects a second user to a second connected dataset, and the first blade and the second blade operate independent of each other, a blade manager for managing the first and second blades, a pipe device for connecting the first and second blades, and logic for sharing portions of the first connected dataset of the first user with the second user using the pipe device.

Abstract: An apparatus, method and computer program product in a content routing system for facilitating transportation of commands having separable segments among a plurality of content nodes comprising detaching the segments prior to the commands being saved to a command memory of a store and forward logic.

Abstract: A variable valve gear for internal combustion engines, having at least one camshaft and pivot lever disposed in the cylinder head, which lever contacts a valve that closes by means of spring force. An intermediate element of a transfer element is mounted in a supporting and displaceable manner, twice on the supporting body and on the pivot lever. The intermediate element engages a supporting surface disposed on the supporting body, first by way of a supporting cam segment disposed on the intermediate element, and second with the controlling cam segment of the supporting body, and third with the pivot lever, by way of an outer contour surface disposed on the intermediate element. The intermediate element indirectly contacts the cam of the camshaft, by way of a roller disposed on an oscillating crank, which is connected with the intermediate element in articulated manner.

Abstract: A method, apparatus and system for routing changes to information between a plurality of content nodes and a command memory of a content router. Content nodes may be user devices (such as mobile phones) and user accounts (such as email accounts). Content nodes may hold one or more content types such as email, contacts, tasks, events and library items. A command memory centralizes conflict detection, resolution and error handling within a content routing system.

Abstract: In one aspect a device such as a mobile device includes logic operable to display an email message received from a remote location, the email message having associated data (e.g., an attachment) located remotely to the device (e.g., with a server or the like). The system further includes logic operable to receive a request for the associated data, and initiate an asynchronous fetch of the associated data, wherein the associated data is fetched in the background of the device. The system may further include logic operable to initiate a notification after receiving the request for the data that the associated data will be fetched, and/or initiate a notification that the associated data has been fetched. The associated data may include an attachment, media object, or other data associated with the email message.

Abstract: System and method for synchronizing a server and one or more user devices in a communication network are disclosed. The system includes a server for communicating with the user device, where the server includes a connected-data-set and the one or more user devices share portions of the connected-data-set, logic for creating a backup of the connected-data-set at the server in accordance with a predetermined backup interval, logic for generating a checkpoint marker for tracking the time intervals when the backup of the connected-data-set is created, and logic for sending the checkpoint marker to the one or more user devices for maintaining a first record of changes to the connected-data-set.

Abstract: An apparatus, method and computer program product for communicating an outgoing command from a command memory of a content router to a content node using a notification signal to a gateway.

Abstract: System and method for providing multiple entry points for connecting one or more user devices in a communication network are disclosed. The method includes providing a server for communicating with the one or more user devices, where the server includes a connected-data-set and the one or more user devices share portions of the connected-data-set, receiving from the user device a request for accessing the connected-data-set from one of the multiple entry points, determining attributes of the user device automatically, selecting a method of communication from a database of predetermined client devices using the attributes of the user device, and provisioning the user device in accordance with the method of communication.

Abstract: System and method for notifying a user status of communications between a server and the user having one or more user devices in a communication network are disclosed. The system includes a server for communicating with the user, where the server includes a connected-data-set and the one or more user devices share portions of the connected-data-set, logic for monitoring communications between the server and the one or more user devices for a predetermined set of notification conditions, and logic for sending a notification message to the one or more user devices when a notification condition is detected.

Abstract: System and method for providing services to a user with one or more user devices in a communication network are disclosed. The system includes a server for communicating with the one or more user devices, where the server includes a connected-data-set and the one or more user devices share portions of the connected-data-set, a configuration database for storing configurations and settings of the one or more user devices, where the configuration database includes type descriptions, transcodings, account templates, service descriptions, and settings of the connected-data-set, and logic for providing services to the one or more user devices using the connected-data-set and the configuration database.

Abstract: The present invention relates to the use of a natriurectic peptide, such as urodilatin, for treating a patient suffering from heart failure, such as acute decompensated heart failure. Preferably, a composition comprising an effective amount of urodilatin is intravenously administered to the patient continuously through a time period of at least 24 hours and up to 120 hours, preferably at least 48 hours.

Abstract: This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.

Abstract: The present invention relates to compounds of formula (I) wherein R1 to R8 and n are as defined in the description and claims, and pharmaceutically acceptable salts and esters thereof. The compounds are useful for the treatment of diseases such as diabetes.

Abstract: The present invention provides compounds of formula I as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R4, A and n have the significance given in the specification. The compounds or their salts may be administered to a patient for treating non-insulin dependent diabetes mellitus.

Abstract: This invention is concerned with compounds of the formula wherein one of R5, R6 and R7 is and R1 to R13, X1, X2, m and n are defined in the description, and all pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPAR? and/or PPAR? agonists.

Abstract: The invention relates to the polypeptide COM and its derivatives, and methods for its preparation and recovery in a pure or partially purified form from body fluids and tissues, and its use as a medicament.