Abstract: The present disclosure relates to IL10 agonists with improved anti-tumor therapeutic efficacy.

Abstract: The present disclosure relates to IL10 agonists with improved anti-tumor therapeutic efficacy. IL10 agonists disclosed herein comprise an IgG Fc domain, a linker moiety, and an IL10 moiety.

Abstract: This disclosure relates to novel triple combination therapies of an oncolytic virus, a PD-1 pathway inhibitor, and a CTLA4 inhibitor for treating or inhibiting the growth of a tumor in a patient with cancer.

Abstract: The invention relates to a repeater system for forwarding radio signals. The repeater system comprises a donor unit for converting the frequencies of the radio signals from the transmission frequency to an intermediate frequency; a server unit for converting the converted radio signals from the intermediate frequency to the transmission frequency; and a cable, which connects the donor unit and the service unit and transmits the converted radio signals over a distance between the donor unit and the service unit at the intermediate frequency. The donor unit has an uplink donor antenna and a separate downlink donor antenna and/or the service unit has an uplink service antenna and, at the same time, a separate downlink service antenna.

Abstract: The present disclosure relates to IL10 agonists with improved anti-tumor therapeutic efficacy.

Abstract: A sensor assembly for mounting a microphone to an aperture of a vehicle trim panel. The microphone is in a housing with an opening permitting ambient sound to reach the microphone. A sound channel has a grid portion in the form of a first radially extending flange at a first end and an engagement portion in the form of a second radially extending flange at the other end which engages a T-slot recess on the underside of the housing. When the engagement portion engages with the T-slot recess and slides to a closed end of the recess, the sound passage is aligned with the microphone.

Abstract: A heterogeneous mobile radio arrangement comprises an antenna arrangement. There is provision for at least one shielded supply cable having a first and a second end, said supply cable being designed to supply the antenna arrangement with electric power, wherein an AISG signal and mobile radio signals are transmittable via the at least one shielded supply cable. There is provision for a first and a second IP converter and a first IP device, wherein both IP converters have a respective IP connection and at least one respective signal line connection. The first IP converter is connectable by its IP connection to a superordinate IP network, and the second IP converter is connected by its IP connection to the at least one first IP device. The signal line connections of the first and second IP converters are electrically connected by means of the shielded supply cable.

Abstract: A heterogeneous mobile radio arrangement comprises an antenna arrangement. There is provision for at least one shielded supply cable having a first and a second end, said supply cable being designed to supply the antenna arrangement with electric power, wherein an AISG signal and mobile radio signals are transmittable via the at least one shielded supply cable. There is provision for a first and a second IP converter and a first IP device, wherein both IP converters have a respective IP connection and at least one respective signal line connection. The first IP converter is connectable by its IP connection to a superordinate IP network, and the second IP converter is connected by its IP connection to the at least one first IP device. The signal line connections of the first and second IP converters are electrically connected by means of the shielded supply cable.

Abstract: Method for topology determination in a mobile communications site, wherein the mobile communications site has n nodes each having m ports. In ‘determining’ (S1), the number of existing nodes is determined. In ‘designating’, one of these nodes is designated as the master node and the others as slave nodes. In ‘selecting’, a slave node is selected as a test slave node and the communication of the other slave nodes is prevented. In ‘testing’, a test is performed to determine via which ports of the master node and via which ports of the test slave node a communication is possible. Thereafter, ‘selecting’ and ‘testing’ are repeated for the other slave nodes, wherein in the method step ‘selecting’, a different slave node is selected as the test slave node in each case. In the method step ‘generating’, a connection topology is then generated for the master node.

Abstract: A sensor assembly for mounting a microphone to an aperture of a vehicle trim panel. The microphone is in a housing with an opening permitting ambient sound to reach the microphone. A sound channel has a grid portion in the form of a first radially extending flange at a first end and an engagement portion in the form of a second radially extending flange at the other end which engages a T-slot recess on the underside of the housing. When the engagement portion engages with the T-slot recess and slides to a closed end of the recess, the sound passage is aligned with the microphone.

Abstract: Individual pieces of position information are used to determine a location using a processor and multiple local position transmitters. The processor is supplied with at least four different navigation signals, each of which corresponds to a satellite signal on the basis of the global navigation satellite system. Each navigation signal contains information on the transmission time and the transmission location. The processor generates at least four modified navigation signals by temporally shifting navigation signals relative to one another such that the target location coordinates which can be obtained therefrom correspond to a target location on the basis of the global navigation satellite system. An analyzer then superimposes the at least four modified navigation signals in order to form a modified summation navigation signal and transmits same to the local position transmitters. The summation navigation signal is calculated individually for each local position transmitter.

Abstract: A control system includes a master, at least one slave, and a communication module arranged between the master and the at least one slave, through which the master and the at least one slave communicate. The master sends control commands for controlling the at least one slave and the at least one slave responds to the control commands of the master. The communication module relays the respective control commands and responses. The master transmits to the communication module in one or a plurality of requests at least one control command and at least one associated timing requirement, the communication module processes the request(s) by sending the at least one control command according to the at least one timing requirement to the at least one slave, and the communication module determines timing information concerning the communication with the at least one slave and sends said timing information to the master.

Abstract: Method for topology determination in a mobile communications site, wherein the mobile communications site has n nodes each having m ports. In ‘determining’ (S1), the number of existing nodes is determined. In ‘designating’, one of these nodes is designated as the master node and the others as slave nodes. In ‘selecting’, a slave node is selected as a test slave node and the communication of the other slave nodes is prevented. In ‘testing’, a test is performed to determine via which ports of the master node and via which ports of the test slave node a communication is possible. Thereafter, ‘selecting’ and ‘testing’ are repeated for the other slave nodes, wherein in the method step ‘selecting’, a different slave node is selected as the test slave node in each case. In the method step ‘generating’, a connection topology is then generated for the master node.

Abstract: Individual pieces of position information are used to determine a location using a processor and multiple local position transmitters. The processor is supplied with at least four different navigation signals, each of which corresponds to a satellite signal on the basis of the global navigation satellite system. Each navigation signal contains information on the transmission time and the transmission location. The processor generates at least four modified navigation signals by temporally shifting navigation signals relative to one another such that the target location coordinates which can be obtained therefrom correspond to a target location on the basis of the global navigation satellite system. An analyzer then superimposes the at least four modified navigation signals in order to form a modified summation navigation signal and transmits same to the local position transmitters. The summation navigation signal is calculated individually for each local position transmitter.

Abstract: A control system includes a master, at least one slave, and a communication module arranged between the master and the at least one slave, through which the master and the at least one slave communicate. The master sends control commands for controlling the at least one slave and the at least one slave responds to the control commands of the master. The communication module relays the respective control commands and responses. The master transmits to the communication module in one or a plurality of requests at least one control command and at least one associated timing requirement, the communication module processes the request(s) by sending the at least one control command according to the at least one timing requirement to the at least one slave, and the communication module determines timing information concerning the communication with the at least one slave and sends said timing information to the master.

Abstract: The invention relates to a plant and to a method for the production of cement clinker from cement raw meal, the cement raw meal being preheated in a preheating zone, precalcined in a calcining zone, completely burned in a sintering combustion zone and cooled in a cooling zone, solid fuels additionally being burned in an additional combustion region, a firing region being used in the additional combustion region, the solid fuel being introduced into the firing region where it forms a fuel bed over which a supplied oxygen-containing gas flows, the resulting combustion products being removed via a discharge opening and being used in the production of cement clinker. The fuel is supplied via a conveyor device arranged outside the firing region, in such a manner that it moves the fuel bed that is present in the direction towards the discharge opening.

Abstract: A multi-beam shape supplementary device for an antenna system for mobile communications includes a site-sharing adapter in the form of a primary adapter. The site-sharing adapter comprises at least two primary terminals for connecting at least two primary control apparatuses. The plug and/or terminal configuration or terminal occupation at the primary terminals are terminal-compatible with the terminals on the coupling terminal side of the site-sharing adapter. The pin or socket terminals provided for the bidirectional signal transmission in the site-sharing adapter are connected to a terminal pin or a terminal socket, provided for the bidirectional signal transmission, of the coupling terminal so as to form a bidirectional signal transmission path. The bidirectional transmission path is configured in such a way that the differentiated communications signals at the at least two primary terminals are converted into frequency-modulated signals.

Abstract: An improved beam shape control device, and more particularly an improved antenna comprising a beam shape control device, is distinguished by the fact that the beam shape control device (RET, M-RET) comprises reading electronics with an RFID receiving antenna and/or writing electronics with an RFID transmitting antenna, by means of which antenna-specific data can be read from an RFID tag positioned in the region of the antenna.

Abstract: An improved beam shape control device, and more particularly an improved antenna comprising a beam shape control device, is distinguished by the fact that the beam shape control device (RET, M-RET) comprises reading electronics with an RFID receiving antenna and/or writing electronics with an RFID transmitting antenna, by means of which antenna-specific data can be read from an RFID tag positioned in the region of the antenna.

Abstract: An antenna transmission control device has a base-station-side and an antenna-side multiplexer circuit. There is an alternating protocol transfer between these two multiplexer circuits to control components close to the antenna. The current-alarmed or protocol-alarmed signals present at the antenna-side terminals of the multiplexer provided on the antenna side can be measured or detected by the multiplexer circuits and supplied to the transmission link together with a terminal-dependent or load-dependent protocol.