Abstract: Computer-implemented methods and apparatus that use neural modulation codes as an alternative to training many individual recognition models or to loosing performance by training mixed models. Large neural models are modulated by codes that model the different conditions. The codes directly alter (modulate) the behavior of connections in a multiconditional perceptual classifier, so as to permit the most appropriate neuronal units and their features to be applied to each condition. The approach may be applied to multilingual ASR, where the resulting multilingual network arrangement is able to achieve performance that is competitive or better than individually trained mono-lingual network. Moreover, the approach requires no adaptation data or extensive adaptation/training time to operate in a manner tuned to each condition. Beyond multilingual speech processing systems the approach can be applied to many other perceptual processing problems (e.g.

Abstract: An in-ear hearing device includes a light source configured to emit light, a photodetector configured to detect the emitted light after the emitted light passes through tissue of a subject, a spout; an audio receiver configured to deliver a sound to the subject through the spout, and a dome configured to conform to a shape of a subject's ear canal when the hearing device is in the ear canal. An output of the light source and an input of the photodetector are separated by the dome, and the dome absorbs and/or reflects at least part of the emitted light. The photodetector may be a forward biased photodiode. The sensor device can be realized with power levels, circuitry components, and in package sizes, of hearing devices.

Abstract: The invention relates to a transmucosal delivery system for idebenone, comprising an external phase, which contains at least one hydrophilic polymer, and an inner hydrophobic phase, which contains idebenone and at least one hydrophobic substance, wherein the inner hydrophobic phase is emulsified in the form of droplets in the external phase. The invention is characterized in that the inner hydrophobic phase is stabilized by at least one emulsifier in the external phase. The invention also relates to a method for producing the same and its use as a medicament.

Abstract: The present invention relates to reagents suitable in the mass spectrometric determination of analyte molecules such as carbohydrates as well as adducts of such reagents and analyte molecules and applications of said reagents and adducts. Further, the present invention relates to methods for the mass spectrometric determination of analyte molecules.

Abstract: Computer-implemented methods and apparatus that use neural modulation codes as an alternative to training many individual recognition models or to loosing performance by training mixed models. Large neural models are modulated by codes that model the different conditions. The codes directly alter (modulate) the behavior of connections in a multiconditional perceptual classifier, so as to permit the most appropriate neuronal units and their features to be applied to each condition. The approach may be applied to multilingual ASR, where the resulting multilingual network arrangement is able to achieve performance that is competitive or better than individually trained mono-lingual network. Moreover, the approach requires no adaptation data or extensive adaptation/training time to operate in a manner tuned to each condition. Beyond multilingual speech processing systems the approach can be applied to many other perceptual processing problems (e.g.

Abstract: A cerumen protection plug for a hearing device. The cerumen protection plug prevents cerumen from passing along a sound conduit in the hearing device and blocking sound output from a receiver in the hearing device. The cerumen protection plug includes a circular plug containing a cerumen barrier. A positioning handle allows the cerumen barrier to be positioned along the sound conduit, where it prevents cerumen that has entered the sound conduit from traveling along the sound conduit to the receiver or an output port of the receiver.

Abstract: A tool for replacing a cerumen filter in a sound conduit of a hearing aid. The tool is designed to position a cerumen filter along the sound conduit and to couple with and remove a cerumen filter that has been positioned along the sound conduit. The tool comprises an insertion tip and an removal tip, both configured to fit inside the sound conduit and to couple or engage with an engagement body extending centrally from the cerumen filter. The tool may be in the form of a stylus with the insertion tip on one and the removing tip on the other end. The tool may also be in the form of a disc dispenser with a plurality of insertion and removal tips attached to the dispenser and accessible for use by rotating plates making up the disc dispenser.

Abstract: An in-ear hearing device includes a light source configured to emit light, a photodetector configured to detect the emitted light after the emitted light passes through tissue of a subject, a spout; an audio receiver configured to deliver a sound to the subject through the spout, and a dome configured to conform to a shape of a subject's ear canal when the hearing device is in the ear canal. An output of the light source and an input of the photodetector are separated by the dome, and the dome absorbs and/or reflects at least part of the emitted light. The photodetector may be a forward biased photodiode. The sensor device can be realized with power levels, circuitry components, and in package sizes, of hearing devices.

Abstract: The present invention relates to an oral thin film comprising at least one cellulose derivative and at least one pharmaceutically active agent, the at least one pharmaceutically active agent having a water solubility of at most 50 g/L at 20° C. and a pH of 6 to 7 and being contained in the oral thin film in an amount of at least 20 wt. % in relation to the total weight of the oral thin film, and to a method for production of said oral thin film, and use thereof as a medicament.

Abstract: A cerumen protection plug for a hearing device. The cerumen protection plug prevents cerumen from passing along a sound conduit in the hearing device and blocking sound output from a receiver in the hearing device. The cerumen protection plug includes a circular plug containing a cerumen barrier. A positioning handle allows the cerumen barrier to be positioned along the sound conduit, where it prevents cerumen that has entered the sound conduit from traveling along the sound conduit to the receiver or an output port of the receiver.

Abstract: A method of customizing a component of a hearing device to the ear of a hearing device user. The method includes the steps of providing the hearing device component as a pre-form including a shape-memory material, heating the hearing device component, and bringing the hearing device component in contact with at least a portion of the ear after reaching a pre-set contact temperature such that the hearing device component conforms to the individual shape of the at least a portion of ear. The shape of the hearing device component is fixed by attending a hardening time of the shape-memory material. Therefore, the hearing device component perfectly fits to the geometry of the user's ear canal.

Abstract: A tool for replacing a cerumen filter in a sound conduit of a hearing aid. The tool is designed to position a cerumen filter along the sound conduit and to couple with and remove a cerumen filter that has been positioned along the sound conduit. The tool comprises an insertion tip and an removal tip, both configured to fit inside the sound conduit and to couple or engage with an engagement body extending centrally from the cerumen filter. The tool may be in the form of a stylus with the insertion tip on one and the removing tip on the other end. The tool may also be in the form of a disc dispenser with a plurality of insertion and removal tips attached to the dispenser and accessible for use by rotating plates making up the disc dispenser.

Abstract: The present application relates to a transdermal therapeutic system comprising a backing layer impermeable to active substances and a polymer matrix on one side of the backing layer impermeable to active substances, wherein the polymer matrix comprises at least one pharmaceutically active substance, at least one inherently non-self-adhesive polymer and at least one plasticizer, said polymer matrix being free of adhesive polymers. The invention further relates to a method of producing the transdermal therapeutic system and to the use thereof as a drug.

Abstract: Disclosed is a multi-layer oral active-substance film comprising at least two non-adhesive layers each containing at least one hydrophilic polymer, and at least one water-soluble adhesive layer containing at least one water-soluble polymer and at least one plasticiser, wherein at least one of the at least two non-adhesive layers and/or the at least one water-soluble adhesive layer contains a pharmaceutically active substance, and wherein the at least two non-adhesive layers and the at least one water-soluble adhesive layer alternate in such a way that the at least one water-soluble adhesive layer is covered on both sides by at least one non-adhesive layer.

Abstract: The present invention relates to reagents suitable in the mass spectrometric determination of analyte molecules such as carbohydrates as well as adducts of such reagents and analyte molecules and applications of said reagents and adducts. Further, the present invention relates to methods for the mass spectrometric determination of analyte molecules.

Abstract: A method of customizing a component of a hearing device to the ear of a hearing device user. The method includes the steps of providing the hearing device component as a pre-form including a shape-memory material, heating the hearing device component, and bringing the hearing device component in contact with at least a portion of the ear after reaching a pre-set contact temperature such that the hearing device component conforms to the individual shape of the at least a portion of ear. The shape of the hearing device component is fixed by attending a hardening time of the shape-memory material. Therefore, the hearing device component perfectly fits to the geometry of the user's ear canal.

Abstract: The invention relates to a transmucosal delivery system for idebenone, comprising an external phase, which contains at least one hydrophilic polymer, and an inner hydrophobic phase, which contains idebenone and at least one hydrophobic substance, wherein the inner hydrophobic phase is emulsified in the form of droplets in the external phase. The invention is characterized in that the inner hydrophobic phase is stabilized by at least one emulsifier in the external phase. The invention also relates to a method for producing the same and its use as a medicament.

Abstract: The present invention relates to an encapulated hearing device (50), e.g. for long-term wear, in which an electronics module (10) is encapsulated into a thermoformed hull (30) by means of an appropriate adhesive (41). This thermoformed hull (30) acts as an improved barrier between the electronics module (10) and the environment of the inner ear, reducing the risk of moisture reaching electrical components.

Abstract: Pinion formed by two joinable parts mountable on a shaft includes a substantially semi-circular first portion of the pinion; a substantially semi-circular second portion of the pinion; the first portion has a first joining surface and a first portion of a hole concentric with the pinion; the second portion has a second joining surface and a second portion of a hole concentric with the pinion; the first joining surface is adapted to be joined to the second joining surface by means of connection means; characterized in that the connection means includes a first bushing and a second bushing; the first bushing is fixed onto said first portion and protrudes from the first joining surface; said second bushing is fixed onto the first or second portion and protrudes from the first or second joining surface.

Abstract: The invention relates to a movement-damping unit (30) comprising a receiving tube (32) having a longitudinal axis (A), a relative movement unit (34) which is received in the receiving tube (32) and which is displaceable back and forth relative to the receiving tube (32) substantially in the direction of the longitudinal axis (A), and a friction device (41) acting between the receiving tube (32) and the relative movement unit (34). According to the invention, the friction device (41) comprises at least one switching element (44, 48) assigned to the relative movement unit (34) and having an engagement portion (48a) formed so as to widen radially in the direction of the longitudinal axis (A), wherein at least one resiliently compressible friction element (46, 50), which comprises a recess (50a) intended for engagement with the engagement portion (48a) and is arranged on the longitudinal face of smaller diameter of the switching element (44, 48), is assigned to each switching element (44, 48).