Patents by Inventor Markus Muller

Markus Muller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200361933
    Abstract: Salts, hydrates and solvates of Compound I and methods of making and using the same and related dosage forms thereof are disclosed.
    Type: Application
    Filed: February 1, 2019
    Publication date: November 19, 2020
    Inventors: Karthik Nagapudi, Yuan Liu, Shuai Wang, Wei Zhang, Fritz Blatter, Srikonda Sastry, Manshiu Leung, Ramachandran Radhakrishnan, Rajendra S. Tandale, Ludwig Pilsl, Roland Müller, Markus Frieser, Christine Czauderna, Lawrence Emerson Fisher
  • Patent number: 10837506
    Abstract: A disc brake for utility vehicles includes a brake disc, a first brake lining on a first side of the brake disc and a second brake lining on a second side of the brake disc opposite the first side. A spreading device is also provided which generates a force that moves the first and the second brake lining away from one another.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 17, 2020
    Assignee: WABCO EUROPE BVBA
    Inventors: Frank Beyer, Jochen Frank, Hans-Christian Jungmann, Marcel Kalmbach, Marcus Keller, Peter Moser, Martin Müller, Vitalij Scherer, Mirko Seip, Markus Stafflinger
  • Patent number: 10830820
    Abstract: A switch circuit includes at least a first and a second switch element connected in series and a switch control configured for providing control signals for switching the first and the second switch element, such that the control signals have a different timing and such that the first and the second switch element perform one joint switch function.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: November 10, 2020
    Assignee: Advantest Corporation
    Inventors: Detlef Müller, Markus Rottacker, Bernhard Mayer
  • Publication number: 20200348133
    Abstract: A coordinate measuring and/or stake out device can be designed for being hand-held (one-handed), free carriage and movement by a user. A position giving means is for determination of an actual translational position of the device using an external position reference and an orientation giving means for determination of an actual rotational position of the device, such that the actual position of the device with respect to all six degrees of freedom of the device can be determined. A radiation source is for generation of a radiation beam as measuring and/or marking beam for measuring and/or visually marking of an object point. A beam steerer is for automatic steering of an alignment of the beam, whereby the beam which differ in the manner of automatic steering the beam alignment.
    Type: Application
    Filed: May 1, 2020
    Publication date: November 5, 2020
    Applicant: LEICA GEOSYSTEMS AG
    Inventors: Stefan EISENREICH, Philipp Lukas RÜST, Matteo CARRERA, Ismail Roman CELEBI, Patrik Titus TÖNGI, Stefan PETKOV, Josef MÜLLER, Markus GESER, Hannes MAAR
  • Publication number: 20200349645
    Abstract: The invention relates to a stock exchange trading platform for a plurality of trader data processing devices that are in communication connection with the trading platform, wherein the trading platform has a trading platform data processing device (“matcher”), which is able to store orders generated by one of the trader data processing devices in an order book, or to fill a matching order that is already recorded in the order book, at least partially, to acknowledge such received orders to the dispatching trader data processing device, and furthermore, to send messages to a plurality of connected trader data processing devices (in the case of a trading system with equally entitled traders, to everybody) in a broadcast mode. The trading platform is in particular characterized in that a unit of the trading data processing device controlling the optional execution or storing of the orders is configured as a dedicated logic circuit.
    Type: Application
    Filed: December 28, 2019
    Publication date: November 5, 2020
    Inventors: Anton Gunzinger, Edgar Blum, Hans Burkhard, Rico Piantoni, David Müller, Markus Berner, Samuel Zahnd
  • Patent number: 10823793
    Abstract: A magnetic resonance scanner has a base, a C-arm mounted on the base, the C-arm having an inner surface curved in a C-shape, the C-shape defining a plane, a magnet mounted on the inner curved surface of the C-arm, the magnet generating a basic magnetic field for magnetic resonance imaging, and a drive mechanism mechanically connected to the magnet. The drive mechanism rotates the magnet around an axis that is orthogonal to the plane so as to selectively position the magnet in at least two magnet positions that are respectively above and beneath a patient, who is situated in the C-arm along or parallel to the axis.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: November 3, 2020
    Assignees: Siemens Healthcare GmbH, Yale University
    Inventors: Stefan Popescu, Markus Vester, Peter Speier, Edgar Müller, Robert Todd Constable, Gigi Galiana
  • Patent number: 10808791
    Abstract: A piston-cylinder assembly includes a cylinder having a cylinder interior filled with a fluid and divided by a piston, which is axially displaceable in cylinder, into a first working space and a second working space. A piston rod is arranged on piston and is guided through second working space and through an end-side second closure in a manner sealed off to the outside at the second end of the cylinder. The retraction stroke of piston and piston rod is restricted by a stop which is arranged in cylinder and against which piston comes to bear directly or indirectly, wherein the axial position of the stop in cylinder is variably adjustable by an adjustment device.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: October 20, 2020
    Assignee: STABILUS GMBH
    Inventors: Lars Löhken, Ulrich Probst, Raphael Piroth, Markus Müller
  • Publication number: 20200325956
    Abstract: A rail brake damper includes a cylinder-piston arrangement. A damping device assigned to the piston comprises at least one damping valve having at least one piston channel, which passes through the piston, connecting the two operating chambers of the cylinder, and a closure element assigned to the piston channel. The closure element is spring pre-loaded with the effect of closing the piston channel and is acted on by the hydraulic pressure which prevails in the operating chamber facing away from the piston rod with the effect of opening the damping valve.
    Type: Application
    Filed: July 12, 2017
    Publication date: October 15, 2020
    Inventors: Ulrich Probst, Lars Löhken, Raphael Piroth, Markus Müller
  • Patent number: 10805747
    Abstract: A method of customizing a component of a hearing device to the ear of a hearing device user. The method includes the steps of providing the hearing device component as a pre-form including a shape-memory material, heating the hearing device component, and bringing the hearing device component in contact with at least a portion of the ear after reaching a pre-set contact temperature such that the hearing device component conforms to the individual shape of the at least a portion of ear. The shape of the hearing device component is fixed by attending a hardening time of the shape-memory material. Therefore, the hearing device component perfectly fits to the geometry of the user's ear canal.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: October 13, 2020
    Assignee: SONOVA AG
    Inventors: Natasha Thumm, Christoph Weder, Markus Muller, Erdal Karamuk, Petra Gunde, Anuja Gopal Shirole
  • Publication number: 20200316674
    Abstract: The object of the invention is a component system for producing a binder for metal casting on the basis of phenolic resins of the benzyl ether type and isocyanates containing non-polar solvents.
    Type: Application
    Filed: December 22, 2017
    Publication date: October 8, 2020
    Inventors: Christian PRIEBE, Jens MÜLLER, Heinz DETERS, Philip SCHNEIDER, Frank LENZEN, Markus DÖRSCHEL
  • Publication number: 20200309878
    Abstract: A magnetic resonance scanner has a base, a C-arm mounted on said base, the C-arm having an inner surface curved in a C-shape, the C-shape defining a plane, a magnet mounted on said inner curved surface of said C-arm, the magnet generating a basic magnetic field for magnetic resonance imaging, and a drive mechanism mechanically connected to the magnet. The drive mechanism rotates the magnet around an axis that is orthogonal to said plane so as to selectively position said magnet in at least two magnet positions that are respectively above and beneath a patient, who is situated in the C-arm along or parallel to the axis.
    Type: Application
    Filed: March 27, 2019
    Publication date: October 1, 2020
    Applicants: Siemens Healthcare GmbH, Yale University
    Inventors: Stefan Popescu, Markus Vester, Peter Speier, Edgar Müller, Robert Todd Constable, Gigi Galiana
  • Publication number: 20200300816
    Abstract: The invention relates to an acoustic emission sensor (100). The acoustic emission sensor comprises an optical resonator (10) having a sensor region (11) configured for reflective operation; an optical waveguide (20) which is optically coupled to the optical resonator (10); a light source (31) which is optically coupled to the optical waveguide (20) to apply light to the optical waveguide (20); and a detection device (32) which is optically coupled to the optical waveguide (20) to detect light from the optical resonator (10). The sensor region (11) of the optical resonator (10) comprises a coupling device (50) for mechanically coupling to a solid measurement object (200). The coupling device (50) comprises a first coupling element (51) for transmitting an acoustic emission signal between the sensor region (11) and the solid measurement object (200), and at least one second coupling element (52).
    Type: Application
    Filed: December 28, 2017
    Publication date: September 24, 2020
    Inventors: Mathias MÜLLER, Markus Schmid, Sascha Kienitz
  • Publication number: 20200297919
    Abstract: A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.
    Type: Application
    Filed: September 28, 2018
    Publication date: September 24, 2020
    Inventors: Markus HEMMINGER, Ulla GRAUSCHOPF, Frank BAMBERG, Mayumi BOWEN, Robert MÜLLER, Flora FELSOVALYI, Denny CHRISTENSEN
  • Patent number: 10781251
    Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: September 22, 2020
    Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
    Inventors: Jörg Wischhusen, Markus Junker, Thomas Müller, Stefan Saremba
  • Publication number: 20200296528
    Abstract: A tool for replacing a cerumen filter in a sound conduit of a hearing aid. The tool is designed to position a cerumen filter along the sound conduit and to couple with and remove a cerumen filter that has been positioned along the sound conduit. The tool comprises an insertion tip and an removal tip, both configured to fit inside the sound conduit and to couple or engage with an engagement body extending centrally from the cerumen filter. The tool may be in the form of a stylus with the insertion tip on one and the removing tip on the other end. The tool may also be in the form of a disc dispenser with a plurality of insertion and removal tips attached to the dispenser and accessible for use by rotating plates making up the disc dispenser.
    Type: Application
    Filed: November 28, 2017
    Publication date: September 17, 2020
    Inventors: Martyn Beedham, Erich Dittli, Andre Ochsenbein, George Meier, Christoph Bosshard, Joseph Muller, Marius Ruefenacht, Erdal Karamuk, Markus Muller
  • Publication number: 20200281867
    Abstract: The present application relates to a transdermal therapeutic system comprising a backing layer impermeable to active substances and a polymer matrix on one side of the backing layer impermeable to active substances, wherein the polymer matrix comprises at least one pharmaceutically active substance, at least one inherently non-self-adhesive polymer and at least one plasticizer, said polymer matrix being free of adhesive polymers. The invention further relates to a method of producing the transdermal therapeutic system and to the use thereof as a drug.
    Type: Application
    Filed: November 21, 2018
    Publication date: September 10, 2020
    Inventors: Michael LINN, Markus MULLER, Marius BAUER
  • Publication number: 20200282130
    Abstract: A method of preparing a prefilled syringe is disclosed that includes obtaining a syringe barrel and a needle adaptor cap assembled on the tip of the syringe barrel, wherein the needle adaptor cap has a rubber element tightly sealing the orifice of the tip of the syringe barrel and the syringe barrel together with the needle adaptor cap assembled on the tip of the syringe barrel is sterilized by a first sterilizing. Filling a drug substance into an interior of the syringe barrel and sealing the interior of the syringe barrel. Packaging the syringe barrel with a rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel. Providing a second external surface sterilizing of the packaged syringe barrel with the rubber stopper sealing the interior thereof and the needle adaptor cap assembled on the tip of the syringe barrel.
    Type: Application
    Filed: September 28, 2018
    Publication date: September 10, 2020
    Inventors: Markus HEMMINGER, Ulla GRAUSCHOPF, Frank BAMBERG, Mayumi BOWEN, Robert MÜLLER, Flora FELSOVALYI, Denny CHRISTENSEN
  • Publication number: 20200281847
    Abstract: Disclosed is a multi-layer oral active-substance film comprising at least two non-adhesive layers each containing at least one hydrophilic polymer, and at least one water-soluble adhesive layer containing at least one water-soluble polymer and at least one plasticiser, wherein at least one of the at least two non-adhesive layers and/or the at least one water-soluble adhesive layer contains a pharmaceutically active substance, and wherein the at least two non-adhesive layers and the at least one water-soluble adhesive layer alternate in such a way that the at least one water-soluble adhesive layer is covered on both sides by at least one non-adhesive layer.
    Type: Application
    Filed: November 21, 2018
    Publication date: September 10, 2020
    Inventors: Michael LINN, Markus MULLER, Marius BAUER
  • Publication number: 20200261460
    Abstract: The invention relates to amorphous folate salt. The salt consists of a folate anion and an organic cation. The folate anion is selected from the group consisting of 5-formyl-(6S)-tetrahydrofolic acid, 10-formyl-(6R)-tetrahydrofolic acid, 5-methyl-(6S)-tetrahydrofolic acid, (6S)-tetrahydrofolic acid, 5,10-Methylene-(6R)-tetrahydrofolic acid, and its oxidized derivatives JK12A and Mefox, and the cation is an organic compound selected from the group arginine, choline, acetylcholine, 1,1-dimethyl-biguanidin and phenylethylbiguanidin. The cation is an organic compound with a complementary pharmacological activity.
    Type: Application
    Filed: August 29, 2018
    Publication date: August 20, 2020
    Inventors: Martin ULMANN, Gerd WIESLER, Arthur BODENMÜLLER, Markus MÜLLER
  • Publication number: 20200231963
    Abstract: The invention relates to novel polypeptide libraries that are conformationally constrained in an anti-parallel, helix-turn-helix arrangement. The invention further relates to methods of generating and screening such libraries for biological, pharmaceutical and other uses.
    Type: Application
    Filed: April 8, 2020
    Publication date: July 23, 2020
    Inventors: Roger Müller, Andreas Bültmann, Josef Prassler, Markus Moosmeier