Patents by Inventor Marlon Cowart

Marlon Cowart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047304
    Abstract: The present invention provides for compounds of formula (I) wherein R1, Y, L1, G1, X1, X2, L2, R2, R3, and R4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).
    Type: Application
    Filed: May 26, 2020
    Publication date: February 18, 2021
    Inventors: Marlon Cowart, Steven Fidanze, Lisa Hasvold, Dachun Liu, Keith McDaniel, John Pratt, George Sheppard, Le Wang
  • Publication number: 20190382383
    Abstract: Provided herein are compounds of formula (I) wherein R1, Y, L1, G1, X1, X2, L2, R2, R3, and R4 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, which are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).
    Type: Application
    Filed: October 14, 2016
    Publication date: December 19, 2019
    Inventors: Marlon Cowart, Steven Fidanze, Lisa Hasvold, Dachun Liu, Keith McDaniel, John Pratt, George Sheppard, Le Wang
  • Patent number: 9777020
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, Z1, Z2, and n are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by Tropomysin receptor kinases (Trk). Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: October 3, 2017
    Assignee: AbbVie Inc.
    Inventors: Robert J. Altenbach, Huaqing Liu, Bruce Clapham, Ana L. Aguirre, Marlon Cowart, John R. Koenig, Kathy Sarris, Marc J. Scanio, Kerren K. Swinger, Anil Vasudevan, Clara I. Villamil, Kevin R. Woller
  • Publication number: 20160376240
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, R2, R3, R4, R5, R6, and X are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by Tropomysin receptor kinases (Trk). Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
    Type: Application
    Filed: January 16, 2015
    Publication date: December 29, 2016
    Applicant: ABBVIE INC.
    Inventors: William Bunnelle, Marlon Cowart, Irene Drizin, John Robert Koenig, Marina Pliushchev, Marc Scanio
  • Publication number: 20150210720
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R1, Z1, Z2, and n are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by Tropomysin receptor kinases (Trk). Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
    Type: Application
    Filed: January 22, 2015
    Publication date: July 30, 2015
    Inventors: Robert J. Altenbach, Huaqing Liu, Bruce Clapham, Ana L. Aguirre, Marlon Cowart, John R. Koenig, Katerina Sarris, Marc J. Scanio, Kerren K. Swinger, Anil Vasudevan, Clara I. Villamil, Kevin R. Woller
  • Publication number: 20080119520
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Application
    Filed: January 29, 2008
    Publication date: May 22, 2008
    Applicant: Abbott Laboratories
    Inventors: Marlon Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie Fernando, Timothy Grieme, Robert Altenbach
  • Publication number: 20080113982
    Abstract: Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
    Type: Application
    Filed: January 15, 2008
    Publication date: May 15, 2008
    Inventors: Chen Zhao, Minghua Sun, Marlon Cowart, Youssef Bennani
  • Publication number: 20080021081
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: June 22, 2007
    Publication date: January 24, 2008
    Inventors: Huaqing Liu, Lawrence Black, Youssef Bennani, Marlon Cowart
  • Publication number: 20070265249
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B1 are as described in the specification.
    Type: Application
    Filed: May 14, 2007
    Publication date: November 15, 2007
    Inventors: Marlon Cowart, Steven Latshaw, Sherry Nelson, Andrew Stewart
  • Publication number: 20070232612
    Abstract: Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands, Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
    Type: Application
    Filed: February 13, 2007
    Publication date: October 4, 2007
    Inventors: Marlon Cowart, Chen Zhao, Minghua Sun, Lawrence Black, Guo Zheng, Robert Gregg, Geoff Zhang, Ahmand Sheikh, Xiaochun Lou, Rodger Henry, David Barnes, Lawrence Kolaczkowski, Anthony Haight, Sou-Jen Chang, Steven Wittenberger, Michael Fickes
  • Publication number: 20070078133
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: June 1, 2006
    Publication date: April 5, 2007
    Inventors: Huaqing Liu, Arthur Hancock, Marlon Cowart, Kathryn Hancock
  • Publication number: 20070066588
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: September 8, 2006
    Publication date: March 22, 2007
    Inventors: Marlon Cowart, Minghua Sun, Chen Zhao, Guo Zheng
  • Publication number: 20060194798
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 5, 2006
    Publication date: August 31, 2006
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Padam Sharma, Youssef Bennani, Michael Curtis
  • Publication number: 20060172995
    Abstract: The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B, are as described in the specification.
    Type: Application
    Filed: March 31, 2006
    Publication date: August 3, 2006
    Inventors: Marlon Cowart, Steven Latshaw, Sherry Nelson, Andrew Stewart
  • Publication number: 20060142325
    Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands and methods for using such compounds and compositions.
    Type: Application
    Filed: February 16, 2006
    Publication date: June 29, 2006
    Inventors: Marlon Cowart, Yi-Yin Ku, Sou-Jen Chang, Dilinie Fernando, Timothy Grieme, Robert Altenbach
  • Publication number: 20050272728
    Abstract: Compounds of formula (I) wherein R1 or R2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L2 and L3, to a heteroaromatic core, and X, X?, Y, Y?, Z, Z?, R1, R2, R3, R3a, R3b, R4, R5, L, L2, and L3 are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 6, 2005
    Publication date: December 8, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050272736
    Abstract: Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X?, Y, Y?, Z, and Z? are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 6, 2005
    Publication date: December 8, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050256118
    Abstract: Compounds of formula (I) wherein R1 or R2 is an aromatic or non-aromatic ring directly joined or joined by a linker, as represented by L2 and L3, to a heteroaromatic core, and X, X?, Y, Y?, Z, Z?, R1, R2, R3, R3a, R3b, R4, R5, L, L2, and L3 are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 12, 2004
    Publication date: November 17, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-Jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-Yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050256309
    Abstract: Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X?, Y, Y?, Z, and Z? are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).
    Type: Application
    Filed: May 12, 2004
    Publication date: November 17, 2005
    Inventors: Robert Altenbach, Lawrence Black, Sou-jen Chang, Marlon Cowart, Ramin Faghih, Gregory Gfesser, Yi-yin Ku, Huaqing Liu, Kirill Lukin, Diana Nersesian, Yu-ming Pu, Michael Curtis
  • Publication number: 20050245495
    Abstract: Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
    Type: Application
    Filed: April 7, 2004
    Publication date: November 3, 2005
    Inventors: Chen Zhao, Minghua Sun, Marlon Cowart, Youssef Bennani