Patents by Inventor Marlon Cowart

Marlon Cowart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azacyclosteroid histamine-3 receptor ligands
    Publication number: 20050227953
    Abstract: Azacyclosteroid histamine-3 receptor ligands, pharmaceutical compositions comprising such compounds, and methods for using such compounds and compositions are described herein.
    Type: Application
    Filed: April 1, 2005
    Publication date: October 13, 2005
    Inventors: Chen Zhao, Minghua Sun, Marlon Cowart, Youssef Bennani
  • Novel amines as histamine-3 receptor ligands and their therapeutic applications
    Publication number: 20050192277
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the treatment of disorders ameliorated by histamine-3 receptor ligands.
    Type: Application
    Filed: April 8, 2005
    Publication date: September 1, 2005
    Inventors: Marlon Cowart, Youssef Bennani, Ramin Faghih, Gregory Gfesser, Lawrence Black
  • Histamine-3 receptor ligands for diabetic conditions
    Publication number: 20050113435
    Abstract: The invention relates to a method of treating a diabetic condition by administering a therapeutically effective amount of a histamine-3 receptor antagonist, including benzofuran and benzopyran derivatives of formula (I), aminoalkoxybiphenylcarboxamide compounds of formula (III), and aminoetherbiphenyl compounds of formula (IV) as described herein.
    Type: Application
    Filed: October 6, 2004
    Publication date: May 26, 2005
    Inventors: Arthur Hancock, Eugene Bush, Marlon Cowart, Peer Jacobson, Terry Opgenorth, Youssef Bennani
  • Process for preparing amine-substituted benzofurans
    Publication number: 20050054677
    Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.
    Type: Application
    Filed: September 21, 2004
    Publication date: March 10, 2005
    Inventors: Yi-Yin Ku, Yu-Ming Pu, Marlon Cowart, Timothy Grieme, Ashok Gupta, Daniel Plata
  • Histamine-3 receptor ligands for diabetes conditions
    Publication number: 20030134835
    Abstract: The invention relates to a method of treating a diabetic condition by administering a therapeutically effective amount of a histamine-3 receptor antagonist, including benzofuran and benzopyran derivatives of formula (I), aminoalkoxybiphenylcarboxamide compounds of formula (III), and aminoetherbiphenyl compounds of formula (IV) as described herein.
    Type: Application
    Filed: January 11, 2002
    Publication date: July 17, 2003
    Inventors: Arthur Hancock, Eugene Bush, Marlon Cowart, Peer B. Jacobson, Terry Opgenorth, Youssef Bennani
  • 2-nitroaryl and 2-cyanoaryl compounds as regulators of nitric oxide synthase
    Patent number: 5362747
    Abstract: 2-Nitroaryl or 2-cyanoaryl compounds of the formula ##STR1## pharmaceutical compositions thereof, intermediates useful in the preparation of these compounds, and methods for treating disorders of vascular smooth muscles or diseases of the cartilage, macrophages, neurons, platelets, bronchial smooth muscles, optic muscles and gastrointestinal smooth muscles, in addition to sickle cell anemia, diabetes, synovitis, chondroarthritis and osteoarthritis by employing these compounds.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: November 8, 1994
    Assignee: Abbott Laboratories
    Inventors: Marlon Cowart, James F. Kerwin