Abstract: Techniques and architecture are described for validating and verifying iPXE scripts prior to execution during a booting process. During the booting process of a network device, right after the UEFI/BIOS stage of the booting process, a trusted iPXE script may make a request to a network server for the ownership voucher and owner certificate of the network device. The ownership voucher and owner certificate may then be stored in a trusted platform module (TPM) on the network device. In configurations, the retrieved owner certificate may be validated by the ownership voucher. The owner certificate may be used to validate iPXE scripts. Once validated, the iPXE scripts may be executed and the booting process may be continued to the kernel loading step and the application loading step. During a subsequent booting process of the network device, the ownership voucher and owner certificate may be retrieved from the TPM.

Abstract: Automated jackstand systems and methods deploy a jackstand to support a front end of a trailer parked at an automated loading dock. The jackstand prevents collapse of the trailer's landing gear and prevents upending of the trailer during loading and unloading. Advantageously, by deploying the jackstand automatically, presence of personnel in the yard where tractors and trailers are moving is not required.

Abstract: An attachment is described for a haircare appliance. The attachment includes an inlet for receiving an airflow, and a plurality of outlets through which the airflow is discharged. The attachment further includes one or more members moveable between a first position and a second position. The airflow is discharged from the outlets in a clockwise direction when the members are in the first position, and the airflow is discharged from the outlets in a counterclockwise direction when the members are in the second position.

Abstract: An interactive toy, system, and method of controlling the same. The interactive toy includes a toy housing comprising therein a function device performing user-perceptible, controllable functions; a control circuit controlling the function device; a rechargeable power source providing operating power to the function device and the control circuit; and a charging circuit for contactless receipt of electrical energy and for charging the rechargeable power source when the interactive toy is positioned in a charging zone of a contactless charging device. The control circuit receives a primary signal indicative of an interaction stimulus; a secondary signal indicative of a position of the interactive toy with respect to the charging zone; and, responsive to the primary signal, controls the function device to perform a user-perceptible function selected based on the secondary signal. The interactive toy system includes an interactive toy and a contactless charging device defining one or more charging zones.

Abstract: A BTLA-binding agent and immunoglobulin heavy chain and light chain polypeptides of the binding agent, as well as methods of using the BTLA-binding agent to treat a disorder or disease that is responsive to BTLA agonism, such as an autoimmune or inflammatory disease.

Abstract: A composition comprising Shigella-Tetravalent (4-valent Shigella) bioconjugates. That encompasses the Shigella O-polysaccharide antigens of serotypes Shigella flexneri 2a, 3a, 6 and Shigella sonnei covalently linked to the protein carrier.

Abstract: Systems and methods are provided for a combined defuel and priority panel for a fueling station. The defuel and priority panel is configured to defuel a compressed natural gas (CNG) vehicle and direct the defueled gas to fuel other CNG vehicles at the panel fueling and defueling site. The defuel and priority panel is also configured to store defueled gas in defuel storage tanks, which can then be used to later fuel CNG vehicles.

Abstract: Methods of producing bioconjugates of O-antigen polysaccharides covalently linked to a carrier protein using recombinant host cells are provided. The recombinant host cells used in the methods described herein encode a particular oligosaccharyl transferase enzyme depending on the O-antigen polysaccharide bioconjugate to be produced. The oligosaccharyl transferase enzymes can be PglB oligosaccharyl transferase or variants thereof. Also provided are compositions containing the bioconjugates, and methods of using the bioconjugates and compositions described herein to vaccinate a subject against extra-intestinal pathogenic E. coli. (ExPEC).

Abstract: Disclosed an improved process for synthesising a nucleic acid strand using cycles of template independent enzyme extension. Having one or more of the amino groups on the base heterocyclic groups masked with protecting groups helps to prevent secondary structure in the extended strand, thereby improving access of the enzyme to the 3? OH terminus for extension.

Abstract: A trailer control box may receive a wireless message from a controller of the tractor. The trailer control box may validate and authenticating the message. The trailer control box may control an emergency-brake valve based on the message when the message is an emergency-brake command. The trailer control box may control a service-brake valve based on the message when the message is a service-brake command. The trailer control box may control at least one switch to operate trailer lights based on the message when the message is a light command. In certain embodiments, autonomous-capable socket is mounted to a trailer and includes: a chamfered outer casing, a plurality of electrical connectors, a service-brake air aperture, and an emergency-brake air aperture. The autonomous-capable socket required a single autonomous connection by an autonomous tractor.

Abstract: A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC).

Abstract: Systems and methods are provided for a combined defuel and priority panel for a fueling station. The defuel and priority panel is configured to defuel a compressed natural gas (CNG) vehicle and direct the defueled gas to fuel other CNG vehicles at the panel fueling and defueling site. The defuel and priority panel is also configured to store defueled gas in defuel storage tanks, which can then be used to later fuel CNG vehicles.

Abstract: Methods of producing bioconjugates of O-antigen polysaccharides covalently linked to a carrier protein using recombinant host cells are provided. The recombinant host cells used in the methods described herein encode a particular oligosaccharyl transferase enzyme depending on the O-antigen polysaccharide bioconjugate to be produced. The oligosaccharyl transferase enzymes can be PglB oligosaccharyl transferase or variants thereof. Also provided are compositions containing the bioconjugates, and methods of using the bioconjugates and compositions described herein to vaccinate a subject against extra-intestinal pathogenic E. coli. (ExPEC).

Abstract: The present invention relates to methods of protein purification, in particular using ion exchange chromatography. Modified proteins and peptide tags suitable for use in purification by ion exchange chromatography are provided, as are related methods.

Abstract: A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC).

Abstract: Automated jackstand systems and methods deploy a jackstand to support a front end of a trailer parked at an automated loading dock. The jackstand prevents collapse of the trailer's landing gear and prevents upending of the trailer during loading and unloading. Advantageously, by deploying the jackstand automatically, presence of personnel in the yard where tractors and trailers are moving is not required.

Abstract: A fuel tank comprises an interior wall, a sump, and a baffle that comprises a center fitting, a full-length containment petal, a partial-length containment petal, a dump tube. The full-length containment petal comprises a full-length side edge, extending radially outward from the center fitting. The partial-length containment petal comprises a partial-length side edge, extending radially outward from the center fitting. The dump tube is connected to the sump. The full-length side edge of the full-length containment petal is longer than the partial-length side edge of the partial-length containment petal. All of the partial-length side edge of the partial-length containment petal is attached to a linear portion of the full-length side edge of the full-length containment petal.

Abstract: A toy system comprising a plurality of toy construction elements, having detachably interconnecting coupling members for creating coherent spatial structures. The plurality of toy construction elements include: an energy source device comprising a housing and an energy transfer circuit therein; and energy distribution devices to provide respective external conductive loops extending outside the housing and defining a respective external energy transfer zone in a proximity of the respective external conductive loops. The energy source device is configured to be brought into operational connection with the energy distribution devices.

Abstract: Provided is a PD-1-binding agent comprising an immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide, as well as related compositions and methods for making and using same.

Abstract: The present invention relates to a method of controlling an ensemble of interacting toy construction models. The interacting toy construction models include toy construction elements having functional toy construction elements, the toy construction elements include coupling members configured for detachably interconnecting the toy construction elements with each other. The functional toy construction elements may perform a function in compliance with a configuration defining a functional behaviour. The method includes configuring the functional toy construction elements in the interacting toy construction models based on information on further functional toy construction elements in said interacting toy construction model to coordinate their functional behaviour in a model-behaviour; and further adapting the model-behaviour based on information on further interacting toy construction models in the ensemble.