Abstract: The present invention relates to a pharmaceutical combination which may be useful for the treatment of diseases which involve cell proliferation, which involve migration or apoptosis of myeloma cells, which involve angiogenesis or which involve fibrosis. The invention also relates to a method for the treatment of said diseases, comprising simultaneous, separate or sequential administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.

Abstract: The present invention relates to a pharmaceutical combination for the treatment of diseases which involves cell proliferation, migration or apoptosis of myeloma cells, or angiogenesis. The invention also relates to a method for the treatment of said diseases, comprising co-administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.

Abstract: The invention relates to a process for identifying and authenticating an object. The object includes an identifier which has a code region and a scattering region and is irradiated with electromagnetic radiation for identifying and/or authenticating the object, in such a manner that the electromagnetic radiation reflected by the code region is used for identifying the object and the electromagnetic radiation reflected by the scattering region is used for authenticating the object.

Abstract: A method and an arrangement for processing a received signal which comprises phase-shift modulated or amplitude-quadrature modulated part-signals which are transmitted in a plurality of different frequency bands, wherein the received signal is processed in a plurality of stages in succession, by multiplying all the input signals to each of the stages by two mutually orthogonal signals in each case to form two intermediate signals in each case, wherein the intermediate signals from one stage in each case act as the input signals to whichever is the succeeding stage in the particular case and the received signal acts as the input signal to the first stage, and wherein an in-phase and/or an quadrature component of the individual part-signals in the different frequency bands are determined from the intermediate signals from the last stage. Parallel, simultaneous reception of a plurality of frequency bands can be implemented relatively easily in this way.

Abstract: A method for handling a liquid, in particular for the metered transfer of a liquid that is viscous at room temperature from a reservoir to a receiving container for the purpose of further processing the viscous liquid. In the method the receiving container is filled with the liquid. In this arrangement the liquid is present in a plurality of individual portions. Furthermore, the liquid is cooled such that the individual portions are present in a predominantly solid state of aggregation. Preferably, the individual portions are sufficiently small so that the transferred liquid is a frozen granulate.

Abstract: Frequency pattern generator (1, 101, 201) for generating frequency pulses, said generator having a first local oscillator unit (2-1, 121, 221) for generating a first radio frequency carrier frequency signal (LO1), at least one second local oscillator unit (2-2, . . . 2-N, 122, 222) for generating at least one second radio frequency carrier frequency signal (LO2), a switching device (3, 103, 203) for passing on one of the radio frequency carrier frequency signals (LO1, LO2) or a zero signal (DC) in a manner dependent on a control signal (CTR), and a mixing stage (9, 109, 209, 212, 309) for mixing the signal (LO) that has been passed on by the switching device (3, 103, 203) with a mixing frequency signal (LF) to form a pulsed output signal (RFOUT), the pulsed output signal (RFOUT) having frequency pulses at a respective frequency (f1, . . . f8) and length (Tp) in a manner dependent on the control signal (CTR).

Abstract: A tool for a resin transfer moulding method comprises a cavity, a resin trap and a transition region, wherein the cavity is designed such that a component can be accommodated in it. Furthermore, the resin trap is integrated in the tool, and the transition region is designed such that with it a connection between the cavity and the resin trap can be established.

Abstract: An implementation of a system and method for processing transfer rides associated with at least one public transit network is provided. The system and method preprocess transactions to consolidate or eliminate unnecessary transactions with a financial institution clearing and settlement network.

Abstract: A docking system for docking a liquid stream carrying line to a docking body, a line end for docking a liquid stream carrying line to a docking interface of a docking body, as well as to a method for preventing liquid from continuing to flow when undocking a line end of a liquid stream carrying line from a docking interface of a docking body. The docking system includes a line end having a first form that is conically tapered in the direction of flow and a docking interface which is situated on the docking body and has a second form that is conically tapered in the direction of flow. The first conically tapered form and the second conically tapered form are adapted to one another in such a way that, in the docked state, they are mutually set apart in one coupling region by an interspace defined by a sealing ring, concentrically opposing one another.

Abstract: This application describes a tool, an arrangement, and a method of manufacturing a component. The manufacturing of the component is achieved by a resin transfer from a storage chamber via a transfer line into a working chamber. Before the resin transfer, taking place, for example by a compressed air charging of the storage chamber, the storage chamber is filled with an amount of resin adjusted to the size of the component. furthermore, a semi-finished product, consisting of cut-to-size reinforcement fibers, is inserted into the working chamber that is adjusted to the form of the component to be produced. Storage chamber, transfer line, and working chamber are configured in a one-piece mould casing of the tool. The application further describes a component manufactured by the above-mentioned tool or by the above-mentioned method respectively.

Abstract: An implementation of a system and method for gating entry in a transit system using information from a bankcard, such as a credit card or debit card is provided.

Abstract: An implementation of a system and method for regulating entry in a transit system using information from a bankcard, such as a credit card or debit card is provided.

Abstract: The invention relates to a method of treating immunologic diseases or pathological conditions involving an immunologic component using certain Lck inhibitors already known as kinase inhibitors for therapy in oncology, optionally in combination with one or more other drugs selected from NSAIDs, steroids, DMARDs, immunsuppressives, biologic response modifiers and antinfectives, pharmaceutical compositions comprising said Lck inhibitors together with said other drugs, and the use of the Lck inhibitors for the manufacture of a pharmaceutical composition for the treatment of immunologic diseases or pathological conditions involving an immunologic component.

Abstract: The present invention relates to a method and a device for placing at least one material layer onto a relief mould for producing a composite material. Thereby, an elastically-reversibly deformable body with a surface relief that is designed to correspond to the relief mould is pressed against the material layer, as a result of which the surface of said body is deformed, and the material layer can be picked up. As a result of its elastically-reversible characteristics the body subsequently deforms back to its initial state so that the material layer can easily be placed onto the relief mould.

Abstract: This invention relates to tablets especially tablets formed by direct compression of a dipeptidylpeptidase IV (DPP-IV) inhibitor compound, a process for the preparation thereof; to new pharmaceutical formulations, and new tableting powders comprising DPP-IV inhibitor formulations capable of being directly compressed into tablets. The invention relates further to a process for preparing the tablets by blending the active ingredient and specific excipients into the new formulations and then directly compressing the formulations into the direct compression tablets. The invention also relates to vildagliptin particle size distribution and a new crystal form of vildagliptin particularly adapted for the preparation of improved tablets and other pharmaceutical compositions.

Abstract: Circuit arrangement for a wideband mixer (1, 101, 201) with a multiplicative mixing stage (2) which exhibits a carrier frequency input (3, 4) for coupling in a differential carrier frequency signal (LOP, LON), a mixing stage input (5, 6) for coupling in a predistorted differential input signal (LFPD, LFND), and an output (9, 10) for coupling out a differential output signal (OUTP, OUTN) which is generated from the differential carrier frequency signal (LOP, LON) and the predistorted differential input signal (LFPD, LFND) by multiplicative mixing, the predistorted differential input signal (LFPD, LFND) being generated from a differential input signal (LFP, LFN) by means of a quadratic predistortion and a linear predistortion.

Abstract: The present invention relates to a pharmaceutical combination for the treatment of diseases which involves cell proliferation, migration or apoptosis of myeloma cells, or angiogenesis. The invention also relates to a method for the treatment of said diseases, comprising co-administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.

Abstract: A method of producing a device with a movable portion spaced apart from a support wafer comprises a step of providing the support wafer having a structured surface and a further step of providing a device wafer with a backing layer and a device layer disposed thereon. Further, the method comprises the step of generating a first planarization layer from a first starting material on the support wafer with a first method to fill in the structures of the structured surface of the support wafer, whereby a surface with a first degree of planarization is obtained. Further, the method comprises a step of generating a second planarization layer from a second starting material on the planarized surface of the support wafer with a second method to obtain a surface with a second degree of planarization, which is higher than the first degree of planarization, wherein the first and second planarization layers can be removed together.

Abstract: An implementation of a system and method for gating entry in a transit system using information from a bankcard, such as a credit card or debit card is provided.

Abstract: An implementation of a system and method for regulating entry in a transit system using information from a bankcard, such as a credit card or debit card is provided.