Abstract: A mass spectrometer is disclosed wherein the experimentally determined mass to charge ratios of ions are reported together with an error band for each mass to charge ratio determination. The error band may, for example, reflect a 95% probability or confidence that the real, true, actual or accepted mass to charge ratio of the ion lies within the error band. By accurately determining the error band the possible candidate ions in a database can be accurately restricted whilst also guarding against over restriction.

Abstract: An ion detector for a mass spectrometer is disclosed comprising a microchannel plate 8 which receives ions 12 at an input surface and releases electrons 16 from an output surface. A detecting device is arranged to receive at least some of the electrons 16 emitted from the microchannel plate 8. The detecting device receives electrons 16 on a first portion of the detecting device at a first time t1 and receives electrons 16 on a second different portion of the detector at a second later time t2. Time-varying electric and/or magnetic fields are applied between the microchannel plate 8 and the detecting device to guide electrons 16 emitted from the microchannel plate onto different regions of the detecting device in a time varying manner.

Abstract: Carbon blacks which are useful in a variety of polymer compounds including ABS compounds are described, as well as methods of making the carbon blacks and polymer compounds. The carbon blacks provide desirable jetness and impact strength, as well as good dispersion in a polymer.

Abstract: A method to produce hydrogen gas or synthesis gas is described and involves the use of a staged reactor. The present invention further relates to effectively running a process such that efficient quantities of hydrogen gas are produced, along with economically useful amounts of carbon black. A combined facility utilizing a carbon black manufacturing plant and a refinery plant are further described, as well as products made by the various methods of the present invention.

Abstract: A mass spectrometer is disclosed wherein the pusher electrode of a Time of Flight mass analyser is operated in conjunction with an ion gate to ensure that low mass background or matrix ions are not injected into the drift region of the mass analyser.

Abstract: A computer virus outbreak is detected by comparing one or more measurement parameters determined over a measurement period against a threshold level. The measurement parameters can include a measurement of how many E-mail messages are sent having an identical file attachment, file type or simply in total. The threshold levels may be varied with the time of day and day of week as well as the tests applied.

Abstract: A long rail pick-up and delivery system providing increased efficiency and safety. The long rail pick-up and delivery system can include a power car, a rail train, a loading car, an unloading car, a transition car and two independent gantries. The dual gantry design allows for simultaneous and independent loading and unloading of long rail on both sides of the long rail pick-up and delivery system. The gantries are operably mounted on a elevated track whereby the gantries are capable to traversing the length of the rail train. The gantries can include booms having multiple degrees of freedom allowing a gripping head to grasp and pull long rail regardless of the resting attitude of the long rail. The long rail pick-up and delivery system can also include additional power cars, an integrated work station and additional gantries.

Abstract: A mass spectrometer is disclosed wherein a z-lens upstream of an orthogonal acceleration Time of Flight mass analyser is repeatedly switched between a first mode wherein ions are transmitted to the mass analyser for subsequent mass analysis with a relatively high transmission and a second mode wherein ions are transmitted with a relatively low transmission. If it is determined that mass spectral data obtained when the mass analyser is in the first mode is suffering from saturation, then suitably scaled mass spectral data obtained when the mass analyser is in the second mode is used instead. If the saturation is severe then the mass spectral data obtained in the first mode may be replaced in its entirety with mass spectral data obtained in the second mode.

Abstract: The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having starch reagents effectively enhance chromatographic detection methods by providing component stability and controlled release. Thus, the novel components and methods disclosed herein provide a completely new modality of chromatographic analyte detection.

Abstract: This invention is based on the discovery that chemokines induce fibroblasts to differentiate to myofibroblasts, which play a critical role in wound healing and are implicated in a number of fibrotic diseases. This activity has been localized to a peptide in the N-terminus of several chemokines. Accordingly, the invention provides polypeptides that induce the differentiation of fibroblasts to myofibroblasts in vitro and in vivo, nucleic acids encoding such polypeptides and related vectors, host cells, and composition containing these components. The invention also encompasses methods for inducing or inhibiting differentiation of fibroblasts to myofibroblasts, in vivo as well as in vitro, and screening methods for identifying other agents that modulate myofibroblast differentiation.

Abstract: The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners effectively enhance chromatographic detection methods by providing component stability and controlled release. Thus, the novel components and methods disclosed herein provide a completely new modality of chromatographic analyte detection.

Abstract: An ion detector 7 for a mass spectrometer is disclosed comprising a microchannel plate 8 which receives ions 12 at an input surface and releases secondary electrons 16 from an output surface. A detecting device 9 having a detecting surface is arranged to receive at least some of the electrons 16 emitted by the microchannel plate 8. The area of the detecting surface is substantially greater than the area of the output surface of the microchannel plate 8.

Abstract: When a computer virus outbreak is detected, a predefined sequence of steps are automatically or manually followed using rule definitions, that may include office hours, to invoke anti-virus counter-measures. The counter-measures can include reducing virus notification, increasing scanning options, blocking E-mail attachments, hiding E-mail address books and the like. The predetermined sequence of actions may be varied with the time of day and day of week.

Abstract: A way of increasing the dynamic range of a mass spectrometer which incorporates a time to digital converter such as commonly used with a time of flight mass analyser is disclosed. A z-lens upstream of the analyser can be switched between a high sensitivity mode wherein a beam of ions passing therethrough is substantially focused on to the entrance slit of the analyser, and a low sensitivity mode wherein the beam of ions is defocused so that the diameter of the beam substantially exceeds that of the entrance slit of the analyser. Obtaining data in the low sensitivity mode in combination with obtaining data in the high sensitivity mode enable an order of magnitude increase in the dynamic range to be obtained.

Abstract: A computer virus outbreak is detected by comparing one or more measurement parameters determined over a measurement period against a threshold level. The measurement parameters can include a measurement of how many E-mail messages are sent having an identical file attachment, file type or simply in total. The threshold levels may be varied with the time of day and day of week as well as the tests applied.

Abstract: A way of increasing the dynamic range of a mass spectrometer which incorporates a time to digital converter such as commonly used with a time of flight mass analyser is disclosed. A z-lens upstream of the analyser can be switched between a high sensitivity mode wherein a beam of ions passing therethrough is substantially focused on to the entrance slit of the analyser, and a low sensitivity mode wherein the beam of ions is defocused so that the diameter of the beam substantially exceeds that of the entrance slit of the analyser. Obtaining data in the low sensitivity mode in combination with obtaining data in the high sensitivity mode enable an order of magnitude increase in the dynamic range to be obtained.

Abstract: A method of determining the arrival time of one or more ions at an ion detector is disclosed. Ions arriving at the ion detector produce a signal and the time when a leading edge of the signal and when a trailing edge of the signal cross an intensity threshold are determined. The two times are then averaged to provide an ion arrival time.

Abstract: A method of forming an annealed high-K metal oxide transistor gate structure is disclosed. A metal oxide layer is formed over a semiconductor substrate. The metal oxide layer undergoes a buffered annealed process in an oxygen atmosphere to anneal the metal oxide layer at or below the thermodynamic chemical equilibrium of SiO/SiO2 and at or above the thermodynamic chemical equilibrium of the metal oxide layer.

Abstract: A mass spectrometer is disclosed wherein the experimentally determined mass to charge ratios of ions are reported together with an error band for each mass to charge ratio determination. The error band may, for example, reflect a 95% probability or confidence that the real, true, actual or accepted mass to charge ratio of the ion lies within the error band. By accurately determining the error band the possible candidate ions in a database can be accurately restricted whilst also guarding against over restriction.

Abstract: The present invention provides a high performance silicon light emitting device. A method and device providing both emission and modulation from a single device is provided, with modulation of the emission characteristics being achieved by application of an electric field across the device, so as to induce quantum confined Stark effects, Franz-Keldysh effects or the like.