Abstract: A gripper includes a main gripper body and at least two gripper fingers, at least one of which is movably mounted on the main gripper body. The gripper has a switch that can be switched between a first switch position and a second switch position, wherein the first switch position, fully releases a pulling device so that by the pulling device being pulled, the gripper finger movably mounted on the main gripper body is pulled into a closed position and the kinematic chain of the finger elements of the movably mounted gripper finger is bent. In the second switch position, a pulling section of the pulling device running along the kinematic chain of the finger elements of the movably mounted gripper finger is locked, so that by the pulling device being pulled, the gripper finger is only pulled into its closed position without the kinematic chain of the finger elements of the gripper finger being bent.

Abstract: This disclosure relates to methods of treatment using compound (1) or analogs thereof, and pharmaceutically acceptable salts thereof. Also disclosed are compounds of formula (10): as defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the same. Methods of treatment, such as for cancer, are provided that comprise administering the compounds and their salts to a subject in need of such treatment.

Abstract: An onboard hydraulic system for an aircraft is disclosed having a motor-pump unit including an electric motor and a hydraulic pump driven by the motor, a hydraulic consumer supplied with pressurized hydraulic fluid from the motor-pump unit, a fluid reservoir, a pressure sensor for sensing pressure of the pressurized hydraulic fluid, a control unit for controlling the motor-pump unit, and a pressure setting mechanism for adapting a pressure setting of the motor-pump unit for ground service or maintenance or specific flight conditions.

Abstract: The present invention relates to a method of storage and/or transport of an ethylenically unsaturated compound, wherein the ethylenically unsaturated compound is protected against undesired free-radical polymerization with a sterically hindered N-oxyl.

Abstract: According to an example, a media loading device may comprise a motor and a leading-edge sensor. The motor may rotate a media roll having a leading-edge in a winding direction and unwinding direction, the motor being controlled by a processor. The leading-edge sensor may comprise a pivot arm and a detecting element. The pivot arm may contact the media roll and the detecting element may issue a leading-edge presence signal to the processor upon contact between the detecting element and the leading-edge occurs.

Abstract: A visualization system includes an observation apparatus having a first image recording device to observe an operation region with a first observation plane, and an endoscope having a probe and a second image recording device to observe the operation region with a second observation plane. A display device represents a first image recorded by the first image recording device in a first orientation and a second image recorded by the second image recording device in a second orientation. The visualization system further includes a tracking system to determine an orientation of the endoscope relative to the observation apparatus and a controller configured to transform the second image based on the orientation of the endoscope relative to the observation apparatus.

Abstract: The invention relates to an adaptation system (500), comprising a mouthpiece (10), configured to be positioned in a mouth of a person, and an external sensoring device (20). The external sensoring device (20) is configured to be positioned at the person, wherein the external sensoring device (20) comprises at least one sensor (22) configured to sense at least one measurable quantity when the mouthpiece (10) is positioned in the person's mouth and the external sensoring device (20) is positioned at the person. Further, the adaptation system (500) comprises an analysis device (30) configured to determine a compliance of the adaptation system and/or to determine an orientation of an upper jaw (100) and a lower jaw (200) to each other derived from the at least one sensed measurable quantity.

Abstract: A rail vehicle for transporting passengers includes at least one car body, a passenger compartment situated in the car body, an underfloor region, an inner ceiling region, and a plurality of device containers for receiving vehicle components. The passenger compartment includes a first end wall region and a second end wall region which is situated opposite the first end wall region. In order to enable a great configuration freedom for the passenger compartment, it is provided that each device container of the rail vehicle is disposed in one of the above-mentioned regions.

Abstract: The present invention relates to the field of therapeutic proteins, in particular, to recombinant coagulation factors. It provides a recombinant Factor VIII (FVIII) protein comprising specific point mutations at defined positions, which serve to reduce the immunogenicity of said FVIII protein, wherein the Factor VIII protein substantially retains its coagulant activity. It further provides nucleic acids encoding said de-immunized protein, cell lines and methods of recombinant preparation as well as pharmaceutical compositions comprising the recombinant FVIII of the invention, which are advantageous for use in treatment of patients with Hemophilia A, particularly those who have not yet been treated with a FVIII product. Additionally, it can be a safe alternative for previously treated patients and even for patients who have developed an immune-response to FVIII, e.g., for immune-tolerance-induction therapy (ITI/ITT) or rescue ITI.

Abstract: Techniques are provided for controlling extraction of landfill gas from a landfill. The techniques include obtaining a measurement of concentrations of oxygen, carbon, and methane in a sample of landfill gas. At least one processor may be used to determine based on the measurement of the concentration of oxygen in the sample, the measurement of the concentration of methane in the sample, and the measurement of the concentration of carbon dioxide in the sample, a balance gas concentration in the sample. Further, the at least one processor may be used to determine whether the determined balance gas concentration in the sample is greater than a balance gas concentration threshold. Responsive to determining that the determined balance gas concentration in the sample is greater than the balance gas concentration threshold, an actuator controls the flow control mechanism to decrease the flow rate of the landfill gas being extracted from the landfill.

Abstract: An agricultural harvester includes a crop processor, a grain tank, an unload conveyor, and an electromagnetic detecting and ranging module positioned at or above a top of the grain tank for detecting a fill level of the grain tank and the location of a receiving vehicle relative to the combine harvester. One or more computing devices receive data from the electromagnetic detecting and ranging module, the data indicating the fill level of the grain tank and the location of the receiving vehicle relative to the combine harvester, and use the data to generate graphic data defining a graphical representation illustrating the relative positions of the unload conveyor and a grain bin of the receiving vehicle. An electronic device including a graphical user interface presents the graphical representation on the graphical user interface.

Abstract: Systems and methods additively manufacturing an object by applying heat to a first plurality of metallic particles in a powder bed using a first heat source, wherein the first heat source is one of multiple heat sources configured into an array, and the first heat source generates a first melt pool. Heat is simultaneously applied to a second plurality of metallic particles in the powder bed using a second heat source of the multiple heat sources in the array to generate a second melt pool. The first plurality of metallic particles are separated from the second plurality of metallic particles by a distance, wherein the distance and an amount of heat from each heat source is controlled to generate a combined melt pool that is larger in size and encompasses the first and second melt pools. The combined melt pool is allowed to solidify to form the object.

Abstract: Materials and methods useful in forming nano-scale features on substrates, and articles such as optical films incorporating such nano-scale patterned substrates.

Abstract: An isolator system, having an isolator (10), which has an interior space (22) for processing a substance, the interior space being delimited by a base-side mounting surface (14) for the arrangement of a substance-processing unit (20) and by an isolator cabin (12) with at least one access opening (24), the access opening being assigned at least one closure device for optionally opening up or blocking the access opening. The isolator cabin can be placed or is placed onto the base-side mounting surface, and wherein the isolator system has at least one quick-change interface (34) for exchanging the isolator cabin (12) for an additional cabin with a different protection level and/or for exchanging the closure device for an additional closure device with a different protection level.

Abstract: A leaf assembly for a multi-leaf collimator comprises a leaf and a leaf nut removably mounted within the profile of the leaf, the leaf nut comprising a threaded hole for receiving a leaf actuator screw oriented along a first axis in the plane of the leaf. The leaf nut is mounted within the leaf such that relative movement between the leaf nut and the leaf is prevented both linearly along the first axis and rotationally about the first axis.

Abstract: An upper link for a three-point power lift of an agricultural tractor including a cylindrical connecting sleeve, a first fastening element rotated into a first open end of the cylindrical connecting sleeve and configured to be attached to the agricultural tractor, a second fastening element rotated into a second open end of the cylindrical connecting sleeve and configured to produce a releasable connection to an attachment, and a retaining bar attached to the first fastening element. The retaining bar includes a bar portion having a locking region for receiving a retaining catch and runs spaced apart along the cylindrical connecting sleeve. The retaining bar includes a support element encompassing the cylindrical connecting sleeve such that the connecting sleeve is rotationally displaceable, and the length of the upper link is varied by rotating the cylindrical connecting sleeve.

Abstract: Embodiments of golf club heads with energy storage characteristics are presented herein. In some embodiments, a golf club head comprises a hollow body comprising a strikeface, a heel region, a toe region opposite the heel region, a sole, a top rail and an inflection point. The inflection point provides increase bending of the strikeface thereby providing performance enhancement over clubs without an inflection point.

Abstract: A substrate processing apparatus including a frame, a first arm coupled to the frame at a shoulder axis having a first upper arm, a first forearm and at least one substrate holder serially and rotatably coupled to each other, a second arm coupled to the frame at the shoulder axis where shoulder axes of rotation of the arms are substantially coincident, the second arm having a second upper arm, a second forearm and at least one substrate holder serially and rotatably coupled to each other, and a drive section connected to the frame and coupled to the arms, the drive section being configured to independently extend and rotate each arm where an axis of extension of the first arm is angled relative to an axis of extension of the second arm substantially at each angular position of at least one of the first arm or the second arm.