Abstract: Systems and methods for generating a 3D model of a dentition are disclosed herein. A method includes generating a first 3D model of a dentition including a plurality of model teeth. The method includes receiving at least one digital representation comprising patient teeth. The method includes determining a virtual camera parameter. The virtual camera parameter corresponds with a camera used to capture the digital representation. The method includes comparing, based on the virtual camera parameter, a first position of a model tooth with a position of a corresponding patient tooth of the digital representation. The method includes moving the model tooth from the first position to a second position. The second position is based on the position of the corresponding patient tooth. The method includes generating a second 3D model comprising the model tooth of the first 3D model in the second position.

Abstract: The present invention provides 1H-pyrazolo[4,3-b]pyridin-7-amines of formula (I) as PDE1 inhibitors together with a second compound which compound is useful in the treatment of a psychiatric disorder and their combined use as a medicament, in particular for the treatment of psychiatric and/or cognitive disorders.

Abstract: This application discloses anti-CCR7 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.

Abstract: An agricultural product delivery applicator for delivering particulate product to a field and including a pneumatic conveying system. The pneumatic conveying system includes an airflow source to provide an airflow, first and second delivery lines operably connected to the airflow source and to a supply compartment. Each delivery line includes a respective supply line and a respective plurality of distribution lines. The pneumatic conveying system further includes first and second distributors coupling the respective supply line with the respective plurality of distribution lines, a first mounting plate coupled to the first distributor and having a first identifier, a second mounting plate coupled to the second distributor and having a second identifier, a first motor having a relation with the first identifier, and a second motor having a relation to the second identifier.

Abstract: Background noise estimators and methods are disclosed for estimating background noise in an audio signal. Some methods include obtaining at least one parameter associated with an audio signal segment, such as a frame or part of a frame, based on a first linear prediction gain, calculated as a quotient between a residual signal from a 0th-order linear prediction and a residual signal from a 2nd-order linear prediction for the audio signal segment. A second linear prediction gain is calculated as a quotient between a residual signal from a 2nd-order linear prediction and a residual signal from a 16th-order linear prediction for the audio signal segment. Whether the audio signal segment comprises a pause is determined based at least on the obtained at least one parameter; and a background noise estimate is updated based on the audio signal segment when the audio signal segment comprises a pause.

Abstract: The present invention relates to a method for producing biocidal, porous particles of a cross-linked polymer, and to the porous particles that can be produced according to the method of the invention. The invention further relates to porous particles of an amino-group-containing polymer (polyamine) having a relatively low swelling factor. The porous particles according to the invention are used to remove biological contaminants from water and to bind metal-containing ions from solutions. The present invention further relates to a filter cartridge which contains the porous cross-linked polymer particles according to the invention.

Abstract: Disclosed herein are methods and systems for conserving energy of a power source of an analyte monitoring device, including entering a power saving mode based on at least one of a temperature level of a power source, a level of power of a power source, or an amount of power needed by at least one component. Also disclosed herein are methods and systems for reducing noise during data transmissions to and from the analyte monitoring device.

Abstract: The present invention is directed to interactive training, and in particular, to methods and systems for computerized interactive skill training. An example embodiment provides a method and system for providing skill training using a computerized system. The computerized system receives a selection of a first training subject. Several related training components can be invoked, such as reading, watching, performing, and/or reviewing components. In addition, a scored challenge session is provided, wherein a training challenge is provided to a user via a terminal, optionally in video form.

Abstract: Examples of methods of hot forming structural components are provided. The methods include heating a blank made from an Ultra High Strength Steel with an aluminum coating and forming the heated blank in a multi-step apparatus.

Abstract: The invention relates to a device for synthesising oligonucleotides, comprising: a reagent container receptacle (1) for holding a reagent container support (17) comprising multiple reagent containers (18); an exchangeable microfluid chip (10) comprising a synthesis chamber, fluid connectors and microfluid valves; a control device (5); fluid connecting means (2); wherein the device can be loaded with the microfluid chip (10) and the reagent container support (17) when in a loading position; a chip receptacle (3).

Abstract: In some examples, a method for operating a gas burner appliance includes determining, on basis of a nominal burner-load and on basis of a mixing ratio of gas and air of a gas/air mixture or a ?-value of the gas/air mixture, a nominal air mass flow in order to provide the nominal burner-load. The method further comprises determining the ambient air pressure and the ambient air temperature of the ambient air, determining, on basis of the ambient air pressure and on basis of the ambient air temperature, the atmospheric density of the ambient air, determining on basis of the nominal air mass flow, on basis of the determined atmospheric density of the ambient air, and on basis of a system resistance of the gas burner appliance, the fan speed of the fan in order to provide the nominal burner-load.

Abstract: A method for detecting an entry into an elevator car of an elevator system by a passenger uses a mobile device carried by the passenger. The mobile device has at least one, but in particular a plurality of sensors, with which the mobile device detects and evaluates measured values. An entry into the elevator car is then detected on the basis of comparing the measured values with at least one stored signal pattern.

Abstract: A hearing aid system configured to compensate for a hearing impairment of a use comprises A) a wearable device adapted for being worn by the user and comprising a1) an input stage comprising at least one input transducer for converting sound around the user to at least one electric input signal representing said sound, and a2) an input stage for providing stimuli representative of a processed version of said least one electric input signal to said user, said stimuli being perceivable by said user as sound; and B) a non-wearable device comprising b1) a processor, and b2) a power supply interface for providing power to the processor. The wearable device and the non-wearable device comprise respective transceiver circuitry for establishing a low latency wireless audio communication link between them.

Abstract: The present disclosure generally relates to user interfaces for managing spatial audio. Some exemplary techniques include user interfaces for transitioning between visual elements. Some exemplary techniques include user interfaces for previewing audio. Some exemplary techniques include user interfaces for discovering music. Some exemplary techniques include user interfaces for managing headphone transparency. Some exemplary techniques include user interfaces for manipulating multiple audio streams of an audio source.

Abstract: An embodiment is directed to a hardware circuit for encrypting and/or decrypting data transmitted between a processor and a memory. The circuit is situated between the processor and memory. The circuit includes a first interface communicatively coupled to the processor via a set of buses. The circuit also includes a second interface communicatively coupled to the memory. The circuit further includes hardware logic capable of executing an encryption operation on data transmitted between the processor and memory, without adding latency to data transmission speed between the processor and the memory. The hardware logic is configured to encrypt data received at the first interface from the processor, and transmit the encrypted data to the memory via the second interface. The hardware logic is also configured to decrypt data received at the second interface from the memory, and transmit the decrypted data to the processor via the first interface.

Abstract: The invention provides novel 6-aryl or 6-heteroaryl 4-morpholin-4-yl-pyhdine-2-one compounds of formula (I), pharmaceutical compositions containing such compounds, and methods for using such compounds in treatment of diseases including cancer, diabetes, inflammatory diseases, neurodegenerative disorders, cardiovascular disorders and viral infections; wherein R1, R2, R3 and R4 are as defined in the specification.

Abstract: A system and method are presented for producing solder paste having undercooled metallic core-shell particles. In one or more arrangements, the system includes a reconstitution assembly, a dispenser assembly, and a mixer, among other components. The reconstitution assembly is configured to place the cores of the solid core metallic core-shell particles into an undercooled liquid state to form a plurality of undercooled metallic core-shell particles. The dispenser assembly is configured to dispense one or more of a set of available flux components. The mixer assembly is configured to mix the one or more of the set of flux components dispensed by the dispenser assembly with the plurality of undercooled metallic core-shell particles formed by the reconstitution assembly to form a solder paste.

Abstract: A telephoto lens having an entrance pupil of between 80 and 110 mm includes a lens head and a focusing component. The lens head, as a first optical assembly, consists of four lens elements with a refractive power sequence that alternates in the light direction. The focusing component is a second optical assembly made of at least two lens elements and has a relative aperture of between 1:4.5 and 1:7.

Abstract: A computing device includes a processor and a machine-readable storage storing instructions. The instructions are executable by the processor to: receive an input string including sensitive data to be encrypted; identify a first portion and a second portion of the input string, the first portion comprising the sensitive data; select, from a plurality of hash functions, a hash function based on the second portion; and generate a hash value of the first portion using the selected hash function.

Abstract: A system for identifying and timing an athlete during a timed sporting event. The athlete is timed using image recognition technology in which one or more images of the athlete taken during the sporting event by a camera (106a, 106b, or 106c) is time-stamped to generate a finish time for the athlete. The athlete is identified by comparing one of the images taken during the sporting event with a profile image of the athlete.