Abstract: The present disclosure relates to compositions, for treating interleukin 5 (IL-5) mediated diseases, and related methods.

Abstract: A mattress topper for providing improved comfort to a sleeper comprises a pressure distribution layer defining an interior volume. The pressure distribution layer has substantially air-impermeable side walls and a substantially air-impermeable base, and a top surface having at least a region that is air permeable. Support material is contained within the interior volume. The mattress topper includes at least one electrically powered air circulation device for drawing air into the interior volume of the pressure distribution layer via at least one air inlet port. A lateral air-flow layer is disposed above the pressure distribution layer and is configured to provide substantially unimpeded air flow both upwardly and laterally.

Abstract: A method and coating system are provided that use a temperature controlled gas flow to smooth a surface of a ceramic, like a thermal barrier coating (TBC). Thermal spray coating unit coats a ceramic on a surface. The thermal spray coating unit creates a flow of ceramic material towards the surface. A layer of at least partially molten ceramic material on the surface is smoothed by transmitting a flow of temperature controlled gas across the at least partially molten ceramic material on the surface after the thermal spray coating of the ceramic on the surface. The solidified ceramic has a smoother surface that requires much less polishing to attain a desired surface roughness.

Abstract: A method and coating system are provided that use a temperature controlled gas flow to smooth a surface of a ceramic, like a thermal barrier coating (TBC). Thermal spray coating unit coats a ceramic on a surface. The thermal spray coating unit creates a flow of ceramic material towards the surface. A layer of at least partially molten ceramic material on the surface is smoothed by transmitting a flow of temperature controlled gas across the at least partially molten ceramic material on the surface after the thermal spray coating of the ceramic on the surface. The solidified ceramic has a smoother surface that requires much less polishing to attain a desired surface roughness.

Abstract: Determining a far field signature of a source array can include receiving data associated with a sea surface state and determining a coherent portion and an incoherent portion of a reflection coefficient of the sea surface based on the received data. A notional source signature of each source of the source array can be determined based on the coherent portion, the incoherent portion, and near field data associated with each of the sources, and the far field signature of the source array can be determined based on the notional source signatures of each of the sources. The notional source signature and the far field signature can be stored. A seismic image of a subsurface location can be generated based on the determined far field signature.

Abstract: An example device in accordance with an aspect of the present disclosure includes an interleaved connector including a plurality of layers of conducting material interspersed with insulating material. A plurality of electrodes are to identify a change in capacitance of the interleaved connector to indicate a penetration of the device.

Abstract: A mattress topper for providing improved comfort to a sleeper comprises a pressure distribution layer defining an interior volume. The pressure distribution layer has substantially air-impermeable side walls and a substantially air-impermeable base, and a top surface having at least a region that is air permeable. Support material is contained within the interior volume. The mattress topper includes at least one electrically powered air circulation device for drawing air into the interior volume of the pressure distribution layer via at least one air inlet port. A lateral air-flow layer is disposed above the pressure distribution layer and is configured to provide substantially unimpeded air flow both upwardly and laterally.

Abstract: A system according to various embodiments can include: a coating system configured to apply a thermal coating material to a component, the component having a plurality of cooling holes; an airflow system coupled with the coating system, the airflow system configured to force air through the component; and a control system coupled with the airflow system and the coating system, the control system configured to: detect coating instructions for the coating system, the coating instructions instructing the coating system to apply the thermal coating material to a subset of the plurality of cooling holes; and instruct the airflow system to force air through the subset of the plurality of cooling holes during application of the thermal coating material to the component in response to detecting the coating instructions.

Abstract: A method of coating a component using a robotic spray system is provided. The robotic spray system includes a scanning apparatus operable to measure and store surface characteristics before and after coating; a robotic arm operable to move the robotic spray system relative to a surface of a component, the component including one or more reference features which remains uncoated during the coating; a spray nozzle operable to deposit a sprayed coating onto the surface; and a device driver module including circuitry configured to operate the scanning apparatus, the robotic arm, and the spray nozzle.

Abstract: A notional source signature of a bubble may be determined. For example, a method for determining a notional source signature of a bubble can include estimating a position of a bubble created by actuation of an impulsive source. A notional source signature of the bubble can be determined based on the estimate.

Abstract: According to examples, an apparatus may include a security enclosure, a main processor housed in the security enclosure, and a physical security monitoring control unit (PSMCU) processor housed in the security enclosure. The PSMCU processor may cause the apparatus to switchably operate between a first mode and a second mode. In the first mode, the PSMCU processor may allow access by the main processor to a first cryptographic key while preventing access by the main processor to a second cryptographic key. In addition, in the second mode, the PSMCU processor may allow access by the main processor to the second cryptographic key while preventing access by the main processor to the first cryptographic key.

Abstract: An airfoil for use in a turbomachine includes a pressure sidewall and a suction sidewall coupled to the pressure sidewall. The suction sidewall and the pressure sidewall define a leading edge and a trailing edge, the leading edge and the trailing edge define a chord distance. The airfoil includes a tip portion extending between the pressure sidewall and the suction sidewall. The tip portion includes a planar section and a recessed section. The recessed section extends adjacent to the planar section such that a thickness of the planar section is less than a thickness of the airfoil. The recessed section is offset a predetermined distance from the leading edge and the trailing edge along the chord distance.

Abstract: According to examples, an apparatus may include a security enclosure, a main processor housed in the security enclosure, and a physical security monitoring control unit (PSMCU) processor housed in the security enclosure. The PSMCU processor may cause the apparatus to switchably operate between a first mode and a second mode. In the first mode, the PSMCU processor may allow access by the main processor to a first cryptographic key while preventing access by the main processor to a second cryptographic key. In addition, in the second mode, the PSMCU processor may allow access by the main processor to the second cryptographic key while preventing access by the main processor to the first cryptographic key.

Abstract: The present disclosure relates to compounds having the Formula (Formula (I)) which are inhibitors of STAT5.

Abstract: Coating systems for components of a gas turbine engine, such as a compressor blade tip, are provided. The coating system can include an abradable material disposed along the compressor blade tip and may be used with a bare compressor casing. The abradable coating is softer than the compressor casing and can reduce the overall rub ratio thereby increasing the lifetime of the compressor blade and casing. Methods are also provided for applying the coating system onto a compressor blade.

Abstract: An airfoil for use in a turbomachine includes a pressure sidewall and a suction sidewall coupled to the pressure sidewall. The suction sidewall and the pressure sidewall define a leading edge and an opposite trailing edge. The leading edge and the trailing edge define a chord distance. The airfoil further includes a root portion, and a tip portion. The tip portion extends between the pressure sidewall and the suction sidewall such that the tip portion is substantially perpendicular to each sidewall. The tip portion includes at least one planar section and at least one oblique section that forms a recess within the tip portion. The at least one oblique section extends from the at least one planar section towards the root portion along the chord distance. The tip portion is configured to reduce airfoil wear during contact with a surrounding casing.

Abstract: This disclosure provides systems and methods of robot calibration using imaging data. A mounting interface attaches to the sensor module to the robot system. A robot includes at least one positioning member, at least one joint connected to the at least one positioning member, at least one actuator for moving the at least one positioning member around the at least one joint, and at least one robot reference mark on the at least one positioning member. The operating environment includes at least three environment reference marks in fixed positions relative to the robot. A camera captures a calibration image and an actual position of the robot is determined based on the robot reference mark relative to the environment reference marks to determine a calibration offset between a reference position and the actual position using the calibration image.

Abstract: A method of coating a component using a robotic spray system is provided. The robotic spray system includes a scanning apparatus operable to measure and store surface characteristics before and after coating; a robotic arm operable to move the robotic spray system relative to a surface of a component, the component including one or more reference features which remains uncoated during the coating; a spray nozzle operable to deposit a sprayed coating onto the surface; and a device driver module including circuitry configured to operate the scanning apparatus, the robotic arm, and the spray nozzle.

Abstract: An electrothermal heater mat (3) is provided for an ice protection system for an aircraft (1) or the like. The heater mat (3) is a laminated heater mat and comprises dielectric layers (50-58), a heater element (501) and a conductive ground plane (71-74) for detecting a fault with the heater element (501). The dielectric layers (50-58) are made of thermoplastic material, and the ground plane (71-74) is formed by spraying metal such as copper onto the thermoplastic material of one of the dielectric layers.

Abstract: An example device in accordance with an aspect of the present disclosure includes an interleaved connector including a plurality of layers of conducting material interspersed with insulating material. A plurality of electrodes are to identify a change in capacitance of the interleaved connector to indicate a penetration of the device.