Patents by Inventor Martin Oft

Martin Oft has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting tumor growth using blocking antibodies to IL-23R
    Patent number: 8034341
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: October 11, 2011
    Assignee: Schering Corporation
    Inventors: Martin Oft, Terrill K. McClanahan
  • Use of Pegylated IL-10 to Treat Cancer
    Publication number: 20110091419
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Application
    Filed: December 22, 2010
    Publication date: April 21, 2011
    Applicant: Schering Corporation
    Inventors: Martin Oft, Catherine Sheppard, John Mumm, Lingling Wu
  • USES OF MAMMALIAN CYTOKINES AND AGONISTS; RELATED REAGENTS
    Publication number: 20100015132
    Abstract: Provided are methods of treatment for tumors. In particular, provided are methods of using of a cytokine molecule and its receptor.
    Type: Application
    Filed: August 27, 2009
    Publication date: January 21, 2010
    Inventor: Martin Oft
  • Uses of IL-23 Agonists and Antagonists; Related Reagents
    Publication number: 20100003251
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor.
    Type: Application
    Filed: August 24, 2009
    Publication date: January 7, 2010
    Applicant: SCHERING CORPORATION
    Inventors: Martin Oft, Terrill K. McClanahan
  • USE OF PEGYLATED IL-10 TO TREAT CANCER
    Publication number: 20090214471
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Application
    Filed: May 11, 2009
    Publication date: August 27, 2009
    Applicant: SCHERING CORPORATION
    Inventors: Martin Oft, Catherine Sheppard, John Mumm, Lingling Wu
  • Methods of Modulating Cytokine Activity; Related Reagents
    Publication number: 20090041718
    Abstract: Provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders, including tumors and cancer. Also provided are methods of administering agonists or antagonists of IL-33 and IL-33 receptor.
    Type: Application
    Filed: September 26, 2008
    Publication date: February 12, 2009
    Applicant: SCHERING CORPORATION
    Inventors: Jochen Schmitz, Martin Oft, Robert A. Kastelein, J. Fernando Bazan
  • Use of Pegylated IL-10 to Treat Cancer
    Publication number: 20080081031
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
    Type: Application
    Filed: September 27, 2007
    Publication date: April 3, 2008
    Applicant: Schering Corporation
    Inventors: Martin Oft, Catherine Sheppard, John Mumm
  • USES OF IL-23 AGONISTS AND ANTAGONISTS; RELATED REAGENTS
    Publication number: 20080057058
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor.
    Type: Application
    Filed: August 31, 2007
    Publication date: March 6, 2008
    Applicant: Schering Corporation
    Inventors: Martin Oft, Terrill McClanahan
  • Uses of IL-23 agonists and antagonists; related reagents
    Patent number: 7282204
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: October 16, 2007
    Assignee: Schering Corporation
    Inventors: Martin Oft, Terrill K. McClanahan
  • METHODS OF MODULATING A MAMMALIAN CYTOKINE
    Publication number: 20070160579
    Abstract: Provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders, including tumors and cancer. Also provided are methods of administering agonists or antagonists of IL-33 and IL-33 receptor.
    Type: Application
    Filed: March 5, 2007
    Publication date: July 12, 2007
    Applicant: Schering Corporation
    Inventors: Jochen Schmitz, Martin Oft, Robert Kastelein, J. Bazan
  • Methods of modulating a mammalian cytokine
    Publication number: 20050203046
    Abstract: Provided are methods of modulating cytokine activity, e.g., for the purpose of treating immune and inflammatory disorders, including tumors and cancer. Also provided are methods of administering agonists or antagonists of IL-33 and IL-33 receptor.
    Type: Application
    Filed: February 15, 2005
    Publication date: September 15, 2005
    Applicant: Schering Corporation
    Inventors: Jochen Schmitz, Martin Oft, Robert Kastelein
  • Uses of mammalian cytokines and agonists; related reagents
    Publication number: 20050048061
    Abstract: Provided are methods of treatment for tumors. In particular, provided are methods of using of a cytokine molecule and its receptor.
    Type: Application
    Filed: July 16, 2004
    Publication date: March 3, 2005
    Inventor: Martin Oft
  • Uses of IL-23 agonists and antagonists; related reagents
    Publication number: 20040223969
    Abstract: Provided are methods of treatment for tumors. In particular, methods are provided for modulating activity of a cytokine molecule and its receptor.
    Type: Application
    Filed: March 9, 2004
    Publication date: November 11, 2004
    Inventors: Martin Oft, Terrill K. McClanahan
  • Pharmaceutical compositions for treating tumour diseases
    Publication number: 20020127542
    Abstract: Pharmaceutical compositions containing as active compound a substance which inhibits the activity of TGF&bgr; on tumour cells of epithelial origin, for the treatment of epithelial, invasive tumour diseases which are characterised by a reversible transition of the cells from an epithelial, non-invasive state into a fibroblastoid, invasive state. The pharmaceutical composition contains a TGF&bgr; inhibitor, preferably combined with an Ras inhibitor. Process for screening substances for the treatment of epithelial, invasive tumour diseases.
    Type: Application
    Filed: March 1, 2002
    Publication date: September 12, 2002
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Hartmut Beug, Martin Oft, Ernst Reichmann, Karl-Heinz Heider
  • Methods of screening for pharmacologically active compounds for the treatment of tumour diseases
    Patent number: 6383733
    Abstract: Pharmaceutical compositions containing as active compound a substance which inhibits the activity of TGF&bgr; on tumour cells of epithelial origin, for the treatment of epithelial, invasive tumour diseases which are characterized by a reversible transition of the cells from an epithelial, non-invasive state into a fibroblastoid, invasive state. The pharmaceutical composition contains a TGF&bgr; inhibitor, preferably combined with an Ras inhibitor. Process for screening substances for the treatment of epithelial, invasive tumour diseases.
    Type: Grant
    Filed: February 16, 1999
    Date of Patent: May 7, 2002
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Hartmut Beug, Martin Oft, Ernst Reichmann, Karl-Heinz Heider