Patents by Inventor Martin R. Prince

Martin R. Prince has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11678890
    Abstract: A thigh compression device and technique to control, time, delay and/or prevent excessive early venous enhancement relative to arterial enhancement and thereby improve and/or enhance MRA images, including peripheral MRA images, is disclosed. In one embodiment, the present invention uses a curved strip of material which is longer on the superior edge and shorter along the inferior edge. When wrapped around the conical shape of the thigh of a subject, for example, a human, the thigh compression device more uniformly conforms to and/or fits around the thigh, providing more even/uniform compression as well as reducing, minimizing and/or eliminating significant movement of the thigh compression device towards the knees of the subject. A snug fit on the thighs may also enable the thigh compression device to be inflated with less fluid, which is faster and less cumbersome for the operator.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: June 20, 2023
    Inventor: Martin R. Prince
  • Publication number: 20130030284
    Abstract: A thigh compression device and technique to control, time, delay and/or prevent excessive early venous enhancement relative to arterial enhancement and thereby improve and/or enhance MRA images, including peripheral MRA images, is disclosed. In one embodiment, the present invention uses a curved strip of material which is longer on the superior edge and shorter along the inferior edge. When wrapped around the conical shape of the thigh of a subject, for example, a human, the thigh compression device more uniformly conforms to and/or fits around the thigh, providing more even/uniform compression as well as reducing, minimizing and/or eliminating significant movement of the thigh compression device towards the knees of the subject. A snug fit on the thighs may also enable the thigh compression device to be inflated with less fluid, which is faster and less cumbersome for the operator.
    Type: Application
    Filed: May 29, 2012
    Publication date: January 31, 2013
    Inventor: Martin R. Prince
  • Patent number: 8200311
    Abstract: Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: June 12, 2012
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Pascal Spincemaille, Yi Wang, Martin R. Prince
  • Patent number: 8190236
    Abstract: There are many inventions described herein as well as many aspects and embodiments of those inventions. A thigh compression device and technique to control, time, delay and/or prevent excessive early venous enhancement relative to arterial enhancement and thereby improve and/or enhance MRA images, including peripheral MRA images. In one embodiment, the present invention uses a curved strip of material which is longer on the superior edge and shorter along the inferior edge. When wrapped around the conical or conal-like shape of the thigh of a subject (for example, a human), the thigh compression device more uniformly conforms to and/or fits around the thigh, providing more even/uniform compression as well as reducing, minimizing and/or eliminating significant movement of the thigh compression device towards the knees of the subject.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: May 29, 2012
    Inventor: Martin R. Prince
  • Publication number: 20120035435
    Abstract: A device is provided for sensing an electrocardiogram signal of a patient. The device includes a substrate and a plurality of electrodes mounted to the substrate. The plurality of electrodes are configured to sense an electrocardiogram signal of a patient when the plurality of electrodes are placed in contact with the patient. The device may include a strap configured to wrap around a portion of the patient wherein the substrate mounts to the strap. The device further may include a respiration sensor mounted to the strap.
    Type: Application
    Filed: January 28, 2010
    Publication date: February 9, 2012
    Inventors: Minkyung Grace Choi, Martin R. Prince
  • Patent number: 8078259
    Abstract: Systems and methods for contrast-enhanced magnetic resonance angiography in which both arterial-phase image data and post-contrast image data is collected.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: December 13, 2011
    Inventor: Martin R. Prince
  • Patent number: 8005530
    Abstract: Technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation. This technique and apparatus allows for imaging the aorta at a fraction of the cost of conventional aortography and without the risks of arterial catheterization or iodinated contrast.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: August 23, 2011
    Inventor: Martin R. Prince
  • Publication number: 20110054301
    Abstract: Systems and methods for contrast-enhanced magnetic resonance angiography in which both arterial-phase image data and post-contrast image data is collected.
    Type: Application
    Filed: March 30, 2010
    Publication date: March 3, 2011
    Inventor: Martin R. Prince
  • Publication number: 20100240985
    Abstract: The present invention is a technique of, and system for, imaging vascular anatomy over distance considerably greater than the maximum practical field of view of a magnetic resonance imaging system while using substantially one contrast agent injection. The technique and system of the present invention acquires image data of a plurality of image volumes which are representative of different portions of the patient's body. The image data of each image volume includes image data which is representative of the center of k-space. The acquisition of image data which is representative of the center of k-space is correlated with a concentration of contrast agent in the artery(ies) residing in the image volume being substantially greater than the concentration of contrast agent in veins and background tissue adjacent to the artery(ies).
    Type: Application
    Filed: June 1, 2010
    Publication date: September 23, 2010
    Applicant: Martin R. Prince
    Inventors: James F.M. Meaney, Martin R. Prince
  • Publication number: 20100174175
    Abstract: Technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation. This technique and apparatus allows for imaging the aorta at a fraction of the cost of conventional aortography and without the risks of arterial catheterization or iodinated contrast.
    Type: Application
    Filed: March 16, 2010
    Publication date: July 8, 2010
    Inventor: Martin R. Prince
  • Patent number: 7747309
    Abstract: The present invention is a method and apparatus for providing preferential enhancement of an artery of interest relative to adjacent veins and background tissue. The method and apparatus adapts the timing of a maximum or substantially elevated rate of infusion to correlate with the collection of image data corresponding to the center of k-space. The technique and apparatus temporally correlates the timing of a maximum or substantially elevated rate of infusion and the mapping of k-space according to the location of the artery of interest, the size of the artery of interest, the physical condition of the patient, the time delay due to the configuration of the contrast agent delivery system, and/or the type of pulse sequence employed by the imaging apparatus.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: June 29, 2010
    Inventor: Martin R. Prince
  • Patent number: 7734078
    Abstract: In time-resolved contrast-enhanced magnetic resonance angiography, a measure quantifying image quality provides a basis for generating a linear filtered composite image by facilitating selection of a mask and an arterial phase image for subtraction. Filtering of individual pixels of a temporal series of images provides enhanced contrast in a single image by allowing the temporal behavior of the pixel intensity to denote representation as an artery, vein or background tissue. Motion artifacts are suppressed by re-registering sequential images, adjusting weighting before averaging and subtraction and filtering the Fourier data to eliminate data corrupted by motion or other phenomena.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: June 8, 2010
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Martin R. Prince, Ramin Zabih, Yi Wang, Richard Watts, Junhwan Kim, Jeff Bezanson, Hale Ersoy
  • Patent number: 7729741
    Abstract: The present invention is a technique of, and system for, imaging vascular anatomy over distance considerably greater than the maximum practical field of view of a magnetic resonance imaging system while using substantially one contrast agent injection. The technique and system of the present invention acquires image data of a plurality of image volumes which are representative of different portions of the patient's body. The image data of each image volume includes image data which is representative of the center of k-space. The acquisition of image data which is representative of the center of k-space is correlated with a concentration of contrast agent in the artery(ies) residing in the image volume being substantially greater than the concentration of contrast agent in veins and background tissue adjacent to the artery(ies).
    Type: Grant
    Filed: December 25, 2007
    Date of Patent: June 1, 2010
    Inventors: James F. M. Meaney, Martin R. Prince
  • Patent number: 7689267
    Abstract: The present invention is a technique and apparatus for providing preferential enhancement of an artery of interest relative to adjacent veins and background tissue by correlating the collection of a predetermined portion of data (for example, image data which is representative of the central portion of k-space) of a magnetic resonance contrast image during the arterial phase of the magnetic resonance contrast enhancement.
    Type: Grant
    Filed: March 25, 2004
    Date of Patent: March 30, 2010
    Inventor: Martin R. Prince
  • Patent number: 7680527
    Abstract: The present invention is a technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation.
    Type: Grant
    Filed: July 26, 2006
    Date of Patent: March 16, 2010
    Inventor: Martin R. Prince
  • Publication number: 20090245606
    Abstract: In time-resolved contrast-enhanced magnetic resonance angiography, a measure quantifying image quality provides a basis for generating a linear filtered composite image by facilitating selection of a mask and an arterial phase image for subtraction. Filtering of individual pixels of a temporal series of images provides enhanced contrast in a single image by allowing the temporal behavior of the pixel intensity to denote representation as an artery, vein or background tissue. Motion artifacts are suppressed by re-registering sequential images, adjusting weighting before averaging and subtraction and filtering the Fourier data to eliminate data corrupted by motion or other phenomena.
    Type: Application
    Filed: June 1, 2009
    Publication date: October 1, 2009
    Applicant: Cornell Research Foundation, Inc.
    Inventors: Martin R. Prince, Ramin Zabih, Yi Wang, Richard Watts, Junhwan Kim, Jeff Bezanson, Hale Ersoy
  • Patent number: 7545967
    Abstract: In time-resolved contrast-enhanced magnetic resonance angiography, a measure quantifying image quality provides a basis for generating a linear filtered composite image by facilitating selection of a mask and an arterial phase image for subtraction. Filtering of individual pixels of a temporal series of images provides enhanced contrast in a single image by allowing the temporal behavior of the pixel intensity to denote representation as an artery, vein or background tissue. Motion artifacts are suppressed by re-registering sequential images, adjusting weighting before averaging and subtraction and filtering the Fourier data to eliminate data corrupted by motion or other phenomena.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: June 9, 2009
    Assignee: Cornell Research Foundation Inc.
    Inventors: Martin R. Prince, Ramin Zabih, Yi Wang, Richard Watts, Junhwan Kim, Jeff Bezanson, Hale Ersoy
  • Publication number: 20080300480
    Abstract: The present invention is a technique of, and system for, imaging vascular anatomy over distance considerably greater than the maximum practical field of view of a magnetic resonance imaging system while using substantially one contrast agent injection. The technique and system of the present invention acquires image data of a plurality of image volumes which are representative of different portions of the patient's body. The image data of each image volume includes image data which is representative of the center of k-space. The acquisition of image data which is representative of the center of k-space is correlated with a concentration of contrast agent in the artery(ies) residing in the image volume being substantially greater than the concentration of contrast agent in veins and background tissue adjacent to the artery(ies).
    Type: Application
    Filed: December 25, 2007
    Publication date: December 4, 2008
    Inventors: James F. M. Meaney, Martin R. Prince
  • Patent number: 7313428
    Abstract: The present invention is a technique of, and system for, imaging vascular anatomy over distance considerably greater than the maximum practical field of view of a magnetic resonance imaging system while using substantially one contrast agent injection. The technique and system of the present invention acquires image data of a plurality of image volumes which are representative of different portions of the patient's body. The image data of each image volume includes image data which is representative of the center of k-space. The acquisition of image data which is representative of the center of k-space is correlated with a concentration of contrast agent in the artery(ies) residing in the image volume being substantially greater than the concentration of contrast agent in veins and background tissue adjacent to the artery(ies).
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: December 25, 2007
    Inventors: James F. M. Meaney, Martin R. Prince
  • Publication number: 20070287907
    Abstract: Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence.
    Type: Application
    Filed: April 20, 2007
    Publication date: December 13, 2007
    Applicant: CORNELL RESEARCH FOUNDATION, INC.
    Inventors: Pascal Spincemaille, Yi Wang, Martin R. Prince