Abstract: The present invention concerns antigen binding proteins specifically binding melanoma associated antigen A (MAGE-A) protein-derived antigens. The invention in particular provides antigen binding proteins which specifically bind to the MAGE-A antigenic peptide comprising or consisting of SEQ ID NO: 1 in a complex with a major histocombatibility (MHC) protein. The antigen binding proteins of the invention contain, in particular, the complementary determining regions (CDRs) of novel engineered T cell receptors (TCRs) that specifically bind to said MAGE-A peptide/MHC complex. The antigen binding proteins of the invention are of use for the diagnosis, treatment and prevention of MAGE-A expressing cancerous diseases. Further provided are nucleic acids encoding the antigen binding proteins of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins of the invention.

Abstract: A storage housing for an electrical energy store of a motor vehicle includes at least one housing part having a circumferential sealing flange, at which the housing part can be connected to at least one additional housing part of the storage housing, The one housing part is formed by a steel frame which is connected to a closing part made of a light metal material, in particular an aluminum material. In order to create a housing part which is optimized in terms of its weight and also in terms of simplicity and sealing, it is provided that the steel frame is designed as a single-piece shaped component made of a steel material.

Abstract: A process for the production of a fluorinated quartz glass including the steps of generating SiO2 particles in a synthesis burner; depositing the resulting SiO2 particles into a body; and vitrifying the resulting body, wherein a fluorinating agent having a boiling point greater than or equal to ?10° C. is supplied to the synthesis burner.

Abstract: Methods are known for producing an anti-resonant hollow-core fiber which has a hollow core extending along a fiber longitudinal axis and an inner jacket region that surrounds the hollow core, said jacket region comprising multiple anti-resonant elements. The known methods have the steps of: providing a cladding tube that has a cladding tube inner bore and a cladding tube longitudinal axis along which a cladding tube wall extends that is delimited by an interior and an exterior; providing a number of tubular anti-resonant element preforms; arranging the anti-resonant element preforms at target positions of the interior of the cladding tube wall, thereby forming a primary preform which has a hollow core region and an inner jacket region; further processing the primary preform in order to form a secondary preform, including an elongation process; and drawing the secondary preform in order to form the hollow-core fiber.

Abstract: The present invention concerns antigen binding proteins directed against PRAME protein-derived antigens. The invention in particular provides antigen binding proteins which are specific for the tumor expressed antigen PRAME, wherein the tumor antigen comprises or consists of SEQ ID NO: 50 and is in a complex with a major histocompatibility complex (MHC) protein. The antigen binding proteins of the invention contain, in particular, the complementary determining regions (CDRs) of novel engineered T cell receptors (TCRs) that specifically bind to said PRAME peptide. The antigen binding proteins of the invention are for use in the diagnosis, treatment and prevention of PRAME expressing cancerous diseases. Further provided are nucleic acids encoding the antigen binding proteins of the invention, vectors comprising said nucleic acids, recombinant cells expressing the antigen binding proteins and pharmaceutical compositions comprising the antigen binding proteins of the invention.

Abstract: A modular system is provided for an energy storage device floor assembly for an electrically operatable passenger car, including a cross-design variant floor assembly which has a main floor and a rear floor. In a first design variant for a passenger car with a solely electric drive, an energy storage device is provided which extends both below the main floor as well as the rear floor, and in a second design variant for a passenger car with a hybrid drive, an energy storage device, which extends solely below the main floor, and a fuel tank, which extends below the rear floor, are provided. A method is disclosed for producing such an energy storage device floor assembly.

Abstract: An energy-store floor assembly for an electrically drivable passenger car, the energy-store floor assembly having a floor assembly, on the bottom side of which an energy storage device of an electric drive of the passenger car is fixed. Lateral side receptacles, in the region of which a separate fastening point is located to which the energy storage device can be fastened, are positioned on the floor assembly. A modular system for manufacturing such an energy-store floor assembly is provided.

Abstract: A securing assembly secures a vehicle battery on a vehicle body, and includes a securing element for securing to a housing of the vehicle battery and a securing unit for detachably securing to a body part of the vehicle body. The securing element and the securing unit are configured so as to be integrally, interlockingly or force-lockingly connected to one another when bringing the vehicle battery into a mounting position.

Abstract: A line arrangement for assembly, for at least partial insertion inside a component and/or for guiding through the inside of a component, particularly a chamber of a bodywork component of a vehicle, includes at least one line which is designed in a non-rigid manner with a plurality of rigid segments and with flexible connection elements that connect to the rigid segments.

Abstract: A line arrangement for assembly, for at least partial insertion inside a component and/or for guiding through the inside of a component, particularly a chamber of a bodywork component of a vehicle, includes at least one line which is designed in a non-rigid manner with a plurality of rigid segments and with flexible connection elements that connect to the rigid segments.

Abstract: A battery storage arrangement for a working device, in particular for a vehicle, includes a battery storage and a carrier. The carrier has a monolithic screwing area having a thread. The battery storage is fastened to the carrier by way of a threaded fastener via the screwing area.

Abstract: A securing assembly secures a vehicle battery on a vehicle body, and includes a securing element for securing to a housing of the vehicle battery and a securing unit for detachably securing to a body part of the vehicle body. The securing element and the securing unit are configured so as to be integrally, interlockingly or force-lockingly connected to one another when bringing the vehicle battery into a mounting position.

Abstract: A wheel unit includes a rotating wheel, a wheel axle, and a location sensor. The rotating wheel rotates with respect to the wheel axle. The location sensor is disposed in a fixed position with respect to the wheel axle. The location sensor determines coordinates for a location of the wheel unit.

Abstract: First, an auxiliary cut-out (11, 16) is formed in a side wall (1) of a continuous casting mold. That cut-out extends, in the longitudinal direction, at least over the cut-out length (L) of the useful cut-out (10) and has an auxiliary cross-section orthogonal to the longitudinal direction. Then, an additional element (13, 14, 17) is inserted into the auxiliary cut-out (11, 16), and extends, in the longitudinal direction, at least over a cut-out length (L) of a later useful cut-out (10) and bounds the useful cut-out (10) orthogonally to the longitudinal direction at least over part of the periphery of the useful cut-out. The useful cut-out (10) is formed by inserting the additional element (13, 14, 17) into the auxiliary cut-out (11, 16). The useful cut-out (10) is closed all around orthogonally to the longitudinal direction. Orthogonally to the longitudinal direction, the useful cut-out has a (correspondingly small) useful cross-section and a maximum useful extent (d3).

Abstract: A monitoring device (6) records variables that are characteristic of operating parameters of a continuous casting mold (1) for casting a metal strand (2). The monitoring device (6) records at least some of the characteristic variables by independently performing measurements during the casting of the metal strand (2). The monitoring device (6) forms groups (G1, G2) of operating parameters and independently tests whether the operating parameters of the respective group (G1, G2) satisfy a respective predetermined stability criterion. The monitoring device (6) accepts the operating parameters into a database (12). The monitoring device (6) determines those data records (11) contained in the database (12) that coincide in their input variables with the basic operating parameters and determines admissible operating parameter ranges for supplementary operating parameters.

Abstract: A radial shaft seal is provided for sealing between high and low pressure sides in an annular space between a shaft and a static structural receiving part, wherein the shaft seal is rotationally symmetric and arranged coaxially to the shaft. A first sealing ring has an inner periphery bulging toward the low pressure side and forms a first sealing lip abutting the shaft. A spacer ring has first and second faces directed towards the high and low pressure sides, respectively. An elastic shaped part has an outer periphery abutting the second face of the spacer ring and an inner periphery bulging toward the high pressure side and abutting the first sealing lip. At least the spacer ring and elastic shaped part define a cavity subjected to the high pressure side or a control pressure which presses the first sealing lip against the shaft via the elastic shaped part.

Abstract: A wheel unit includes a rotating wheel, a wheel axle, and a location sensor. The rotating wheel rotates with respect to the wheel axle. The location sensor is disposed in a fixed position with respect to the wheel axle. The location sensor determines coordinates for a location of the wheel unit.

Abstract: A monitoring device (6) records variables that are characteristic of operating parameters of a continuous casting mold (1) for casting a metal strand (2). The monitoring device (6) records at least some of the characteristic variables by independently performing measurements during the casting of the metal strand (2). The monitoring device (6) forms groups (G1, G2) of operating parameters and independently tests whether the operating parameters of the respective group (G1, G2) satisfy a respective predetermined stability criterion. The monitoring device (6) accepts the operating parameters into a database (12). The monitoring device (6) determines those data records (11) contained in the database (12) that coincide in their input variables with the basic operating parameters and determines admissible operating parameter ranges for supplementary operating parameters.

Abstract: The invention relates to a battery comprising an electrode separator arrangement filled with an electrolyte, characterized in that the electrode separator arrangement is at least partially covered with a casting compound (FIG. 6a). The invention also relates to a method for producing such a battery.

Abstract: A noncontact object scanning system includes a horizontal table rotatable on a vertical axis, one or more scanners above the table and one or more scanners below the table. The table allows passage of radiant energy therethrough due to its transparency or construction as a nonreflective grid. A controller automatically steps the scanners through a scanning sequence, each scan associated with a segment of the object's exterior surface. Surface segments scanned from above the table and from below the table combine to provide a comprehensive scan of the entire exterior surface. Adjacent surface segments overlap one another to provide redundant data used to overcome shadowing effects from the grid and to accurately align and merge the segments into a three dimensional representation of the complete exterior shape of the object. The scanners can incorporate color responsive light detectors whereby the three dimensional representation portrays color and shape.