Abstract: The present invention relates to a solid oral dosage form comprising an extended-release tablet core that is coated with an immediate-release coating, wherein said extended-release tablet core comprises at least one vitamin B12 depleting drug, and wherein said immediate-release coating comprises vitamin B12 or a spray dried formulation thereof. In a preferred embodiment, the vitamin B12 depleting drug is metformin or a pharmaceutically acceptable salt thereof.

Abstract: A method for processing images comprising: capturing a plurality of degraded images of a first real-world environment with a first sensor; processing each degraded image with a first, untrained convolutional neural network, via a Deep Image Prior approach, to obtain a plurality of clean images, wherein each clean image corresponds to a degraded image; pairing each clean image with its corresponding degraded image to create a plurality of degraded/clean image pairs; training, via a supervised learning approach, a machine learning model to learn a function for converting degraded images into restored images based on the plurality of degraded/clean image pairs; capturing a second plurality of degraded images of a second real-world environment; and using the trained machine learning model to convert the second plurality of degraded images into restored images based on the learned function.

Abstract: A codeless video game method may include receiving an arbitrary game image previously unknown to the computer system and containing object images, each object image corresponding to a game element of the video game, each game element associated with at least one property, and associating automatically each object image with a respective game element that corresponds thereto by identifying automatically, in the game image, each object image. Then a program of instructions is generated that is executable by the computer system, which defines behavior of game elements in the video game according to the at least one property associated with the game elements. During a playing of the video game, the program of instructions causes each game element to be represented in the display by the object image, which may be substantially identical to the game object images that were input as part of the overall game image.

Abstract: One disclosed example provides a head-mounted device configured to control a plurality of light sources of a handheld object and acquire image data comprising a sequence of environmental tracking exposures in which the plurality of light sources are controlled to have a lower integrated intensity and handheld object tracking exposures in which the plurality of light sources are controlled to have a higher integrated intensity. The instructions are further executable to detect, via an environmental tracking exposure, one or more features of the surrounding environment, determine a pose of the head-mounted device based upon the one or more features of the surrounding environment detected, detect via a handheld object tracking exposure the plurality of light sources of the handheld object, determine a pose of the handheld object relative to the head-mounted device based upon the plurality of light sources detected, and output the pose of the handheld object.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: A system and method is provided for controlling an automated warehouse or order fulfillment facility. The system includes a sequencing tower, which functions as a buffer for inbound items and shipping containers, and various pick/decant workstations which are connected between the sequencing tower and an automated storage and retrieval system (ASRS). The sequencing tower is adapted for receiving, storing, and releasing newly erected shipping containers and inbound vendor cases. The pick/decant workstations function as a hub between the sequencing tower and the ASRS, where operators at the pick/decant workstations pick order items to shipping containers to fulfil orders or pick inbound/vendor items to inventory containers to be stored in the ASRS. The system and methods synchronize the sequencing tower and ASRS to release items to arrive at the workstations simultaneously to optimize efficiency and throughput of the facility.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed for performing a machine learning operation using storage element pointers. An example computer readable medium comprises instructions that when executed, cause at least one processor to select, in response to a determination that a machine learning operation is to be performed, create first and second storage element pointers based on a type of machine learning operation to be performed, remap input tensor data of the input tensor based on the first storage element pointer without movement of the input tensor data in memory, cause execution of the machine learning operation with the remapped input tensor data to create intermediate tensor data, remap the intermediate tensor data based on the second storage element pointer without movement of the intermediate tensor data in memory, and provide the remapped intermediate tensor data as an output tensor.

Abstract: Systems and methods that employ an autonomous robotic vehicle (ARV) alone or in combination with a remote computing device during the installation of electronic shelf labels (ESLs) in a facility are discussed. The ARV may detect pre-existing product information from paper labels located on modular units prior to their removal and then detect the location of electronic shelf labels (ESLs) after installation. Pre-existing product information gleaned from the paper labels is associated with the corresponding ESLs. The ARV may also determine compliance or non-compliance of modular units to which an ESL is affixed with a planogram of the facility.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: A method for determining a sealing tightness of a fuel cell stack includes providing of fuel into a cathode space, sealed off gas-tight against further components of a cathode subsystem, formed at least partly by the fuel cell stack, and detecting of a value which is indicative of a pressure change in the cathode space, where a cathode test pressure in the cathode space is higher than a pressure outside the fuel cell stack.

Abstract: The present invention encompasses compounds of the formula I which are suitable for the treatment of diseases related to Vanin, and processes for making these compounds, pharmaceutical preparations containing these compounds, and their methods of use.

Abstract: A rotary steerable system (RSS) including an upper stabilizer connected to a collar of a drill string, an articulated section connected by a flexible joint to the collar, a drill bit connected to the articulated section opposite from the flexible joint, a lower stabilizer located proximate to the flexible joint and an actuator located with the articulated section and selectively operable to tilt an axis of the drill bit and the articulated section relative to the collar. A method includes drilling with the RSS a bias phase of a drilling cycle on a demand tool face and drilling a neutral phase of the drilling cycle on a 180 degree offset tool face from the demand tool face.

Abstract: The invention relates to the processing of fluid biological media, especially of culture media or cell- or virus suspensions, potentially containing active pathogens, with the aim of inactivating these pathogens and/or modifying ingredients in these biological media by thermal or radiological treatment.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed that increase utilization of neural network (NN) accelerator circuitry for shallow layers of an NN by reformatting one or more tensors. An example apparatus includes parameter determining circuitry to determine a width of a weight kernel and to determine a depth of a first tensor. The example apparatus also includes storage control circuitry to, starting at a first XY location of the first tensor, copy one or more Z values, up to the depth of the first tensor, of consecutive XY locations that overlap the width of the weight kernel and to load the one or more Z values consecutively in a first XY location of a second tensor.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed that increase data reuse for multiply and accumulate (MAC) operations. An example apparatus includes a MAC circuit to process a first context of a set of a first type of contexts stored in a first buffer and a first context of a set of a second type of contexts stored in a second buffer. The example apparatus also includes control logic circuitry to, in response to determining that there is an additional context of the second type to be processed in the set of the second type of contexts, maintain the first context of the first type in the first buffer. The control logic circuitry is also to, in response to determining that there is an additional context of the first type to be processed in the set of the first type of contexts maintain the first context of the second type in the second buffer and iterate a pointer of the second buffer from a first position to a next position in the second buffer.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed to debug a hardware accelerator such as a neural network accelerator for executing Artificial Intelligence computational workloads. An example apparatus includes a core with a core input and a core output to execute executable code based on a machine-learning model to generate a data output based on a data input, and debug circuitry coupled to the core. The debug circuitry is configured to detect a breakpoint associated with the machine-learning model, compile executable code based on at least one of the machine-learning model or the breakpoint. In response to the triggering of the breakpoint, the debug circuitry is to stop the execution of the executable code and output data such as the data input, data output and the breakpoint for debugging the hardware accelerator.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.

Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds.