Abstract: A saliva-based testing method that bypasses the need for RNA isolation/purification is described herein. In experiments with inactivated SARS-CoV-2 virus spiked into saliva, this method has a limit of detection of 500-1000 viral particles per mL, rivalling the standard NP swab method. Initial studies showed excellent performance with 100 clinical samples. This saliva-based process is operationally simple, utilizes readily available materials, and can be easily implemented by existing testing sites thus allowing for high-throughput, rapid, and repeat testing of large populations.

Abstract: An automatic valve actuator unit and method for use with an associated manual shutoff valve configured to permit or restrict the flow of fluid through an associated supply pipe. The unit comprises a housing, an attachment mechanism for securing the housing to at least one of the associated supply pipe or manual shutoff valve, and an actuator at least partially supported in the housing and having an output shaft extending from the housing. The output shaft includes a locating member supported at a distal end thereof for non-rotatingly engaging a surface of a valve handle of the associated manual shutoff valve adjacent a point of attachment of the handle to the associated manual shutoff valve, the locating member configured to center the output shaft over an axis of rotation of the handle of the associated manual shutoff valve.

Abstract: An automated method for performing an assay of the present disclosure can be performed in a microfluidic device that is a lateral flow device having numerous features to ensure correct operation of the device under gravity, such as vent pockets for enabling the flow of sample fluid from one chamber to the next when the vent pocket is unsealed. Each chamber can have a reagent recess proximal to an inlet end of the chamber. A reagent pellet formed in a reagent recess can be effectively mixed with a sample as the sample flows into the chamber. A flexible circuit with patterned metallic electrical components disposed on a heat stable material can be in direct contact with fluid in the chambers and has resistive heating elements aligned with, for example, a chamber for performing an amplification reaction.

Abstract: A lateral flow assay device of the present disclosure has numerous features to ensure correct operation of the device under gravity, such as vent pockets for enabling the flow of sample fluid from one chamber to the next when the vent pocket is unsealed. The vent pockets have protrusions to help prevent accidental resealing. The device also can have a gasket to ensure free air movement between open vent pockets. Flow control features that protrude horizontally into a chamber proximal to an outlet act to deflect the flow to the side of the chamber opposite from the outlet, prior to the flow entering the outlet. Such features can reduce the flow velocity of the sample fluid and increase the effective fluid flow path length, enhance mixing of reagents with a sample, and enabling more accurate control of fluid flow in the device.

Abstract: Systems and methods are described herein to control brightness based on image content or other inputs to a display system. A dual-control system may integrate both slow control operations and fast control operations into a cohesive brightness management system. By using both shorter-term (e.g., fast control) and longer-term (e.g., slow control) brightness adjustment operations, the electronic device may quickly respond to high luminance and high brightness situations that may cause burn-in into the display, image artifacts, or other damage. Responding quickly to these high consumption situations may prevent damage or perceivable upset to an ongoing process, among other benefits.

Abstract: Embodiments of golf club heads with energy storage characteristics are presented herein. In some embodiments, a golf club head comprises a hollow body comprising a strikeface, a heel region, a toe region opposite the heel region, a sole, a top rail and an inflection point. The inflection point provides increase bending of the strikeface thereby providing performance enhancement over clubs without an inflection point.

Abstract: A microelectronic device comprises a stack structure, a staircase structure, a first liner material, an etch stop structure, and conductive contact structures. The stack structure includes conductive structures and insulative structures arranged in tiers. The stack structure includes sidewalls horizontally bounding the staircase structure. The staircase structure has steps includes edges of tiers of the stack structure. The first liner material is on the steps and the sidewalls and includes horizontally extending portions on the steps and vertically extending portions on the sidewalls. The etch stop structure is on the horizontally extending portions of the first liner material, the vertically extending portions of the first liner material being free of the etch stop structure. The conductive contact structures extend through the etch stop structure and the first liner material and to the conductive structures.

Abstract: Narrow bandgap n-type small molecules are attracting attention in the near-infrared organic optoelectronics field, due to their easy tunable energy band with a molecular design flexibility. However, only a few reports demonstrate narrow bandgap non-fullerene acceptors (NFAs) that perform well in organic solar cells (OSCs), and the corresponding benefits of NFA photodiodes have not been well investigated in organic photodetectors (OPDs). Here, the ultra-narrow bandgap NFAs CO1-4F, CO1-4Cl and o-IO1 were designed and synthesized for the achieved efficient near-infrared organic photodiodes such as solar cells and photodetectors. Designing an asymmetrical CO1-4F by introducing two different ?-bridges including alkylthienyl and alkoxythienyl units ultimately provides an asymmetric A-D?-D-D?-A molecular configuration. This enables a delicate modulation in energy band structure as well as maintains an intense intramolecular charge transfer characteristic of the excited state.

Abstract: Spherical grains and sacrificial particles are mixed in a suspension. The sacrificial particles are larger than the spherical grains. The suspension is injected into a channel in a microfluidic chip, and the spherical grains form microporous structures in the channel. The microporous structures are sintered in the channel. A solvent is injected into the channel, and the solvent dissolves the sacrificial particles and forms macropores between at least some of the microporous structures, thereby forming a mixed-porosity microfluidic chip.

Abstract: A data structure comprising two or more sub data structures representing a given data set is maintained. Each of the two or more sub data structures comprises an array of bit positions and has a set of hash functions associated therewith. Each of the hash functions is operable to map an element of the given data set to at least one of the bit positions of the array. One of the two or more sub data structures is recognized as a master sub data structure and the others of the two or more sub data structures as slave sub data structures. Insertion and deletion of elements in the data structure is based on the recognition of each of the two or more sub data structures as the master sub data structure or one of the slave sub data structures.

Abstract: Systems and methods related to computer peripheral devices and mounts are described including device mounts with three linkages. A first linkage may include a body, an abutment piece approximately perpendicular to the body, and a device attachment mechanism disposed proximate to said abutment piece. A second linkage is rotatably connected to the first linkage and a third linkage is rotatably connected to the second linkage. The third linkage may at least partially overlaps the second linkage and extend beyond an end of the second linkage. A camera housing may also be attached to the first linkage, e.g. by a hinge or socket joint. The second linkage may be connected to the first linkage via a friction hinge, and the third linkage may be connected to the second linkage via another friction hinge. The third linkage may preferably include a substantially planar contact surface with a chamfered leading edge.

Abstract: Systems and methods related to computer peripheral devices and mounts are described including device mounts with three linkages. A first linkage may include a body, an abutment piece approximately perpendicular to the body, and a device attachment mechanism disposed proximate to said abutment piece. A second linkage is rotatably connected to the first linkage and a third linkage is rotatably connected to the second linkage. The third linkage may at least partially overlaps the second linkage and extend beyond an end of the second linkage. A camera housing may also be attached to the first linkage, e.g. by a hinge or socket joint. The second linkage may be connected to the first linkage via a friction hinge, and the third linkage may be connected to the second linkage via another friction hinge. The third linkage may preferably include a substantially planar contact surface with a chamfered leading edge.

Abstract: Poles for supporting electric transmission lines and a method for forming such poles are provided. An exemplary pole includes a center shaft and a first modular support shaft. The first modular support shaft surrounds more or less of the length of the center shaft and includes a plurality of first panels.

Abstract: A type of relief engraved doorplate, comprising an inside plate that is composed of a first Bakelite layer and a second Bakelite layer, said first Bakelite layer and second Bakelite layer being composed of coarse wood dust and fine wood powder respectively, the second Bakelite layer enveloping the exterior of the first Bakelite layer before they are subjected to heated compression molding to obtain the relief engraved pattern on the top and bottom panels of the inside plate; and, at least one pair of outside decorative plates, including at least a layer of thin wood plate and a layer of water-resistant paper, the water-resistant paper being glued onto the thin wood plate and put in a compression mold with a pattern that is opposite to that of the inside plate, to obtain a depressed pattern on one side of the outside decorative plate, which is opposite to the relief engraved pattern on the inside plate, and then it is fitted to the top and bottom panels of the inside plate and subjected to compression molding