Patents by Inventor Martine Barth

Martine Barth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEAR RECEPTOR MODULATORS
    Publication number: 20230066771
    Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.
    Type: Application
    Filed: July 23, 2021
    Publication date: March 2, 2023
    Inventors: Maria A. Argiriadi, Eric C. Breinlinger, Kevin P. Cusack, Adrian D. Hobson, Dominique Potin, Martine Barth, Jerome Amaudrut, Olivia Poupardin, Laurent Mounier, Michael E. Kort
  • INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF CANCER
    Publication number: 20210323982
    Abstract: The invention relates to compounds of formula (I): wherein R1, R2, R3, R4, R5 and are as defined in the description.
    Type: Application
    Filed: October 2, 2019
    Publication date: October 21, 2021
    Inventors: Martine BARTH, Sylvie CONTAL, Jean-Louis JUNIEN, Christine MASSARDIER, Christian MONTALBETTI, Anne SOUDE
  • NUCLEAR RECEPTOR MODULATORS
    Publication number: 20210130293
    Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.
    Type: Application
    Filed: October 16, 2019
    Publication date: May 6, 2021
    Inventors: Maria A. Argiriadi, Eric C. Breinlinger, Kevin P. Cusack, Adrian D. Hobson, Dominique Potin, Martine Barth, Jerome Amaudrut, Olivia Poupardin, Laurent Mounier, Michael E. Kort
  • NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
    Publication number: 20200115353
    Abstract: The invention relates to compounds of formula: wherein R1 to R7 are as defined in the description. These compounds are useful as inhibitors of the YAP/TAZ-TEAD interaction.
    Type: Application
    Filed: April 6, 2018
    Publication date: April 16, 2020
    Inventors: Martine BARTH, Slyvie CONTAL, Jean-Louis JUNIEN, Christine MASSARDIER, Christian MONTALBETTI, Anne SOUDE
  • Compounds as inhibitors of the YAP/TAZ-TEAD interaction and their use in the treatment of malignant mesothelioma
    Patent number: 10414739
    Abstract: The invention relates to compounds of formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined in the description. The compounds of formula (I) are inhibitors of the YAP/TAZ-TEAD interaction.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: September 17, 2019
    Assignee: INVENTIVA
    Inventors: Martine Barth, Sylvie Contal, Christian Montalbetti, Luc Spitzer
  • NUCLEAR RECEPTOR MODULATORS
    Publication number: 20190055196
    Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.
    Type: Application
    Filed: August 22, 2018
    Publication date: February 21, 2019
    Inventors: Maria A. Argiriadi, Eric C. Breinlinger, Kevin P. Cusack, Adrian D. Hobson, Dominique Potin, Martine Barth, Jerome Amaudrut, Olivia Poupardin, Laurent Mounier, Michael E. Kort
  • Nuclear receptor modulators
    Patent number: 10106501
    Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: October 23, 2018
    Assignee: AbbVie Inc.
    Inventors: Maria A. Argiriadi, Eric C. Breinlinger, Kevin P. Cusack, Adrian D. Hobson, Dominique Potin, Martine Barth, Jerome Amaudrut, Olivia Poupardin, Laurent Mounier, Michael E. Kort
  • NEW COMPOUNDS INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF MALIGNANT MESOTHELIOMA
    Publication number: 20180297964
    Abstract: The invention relates to compounds of formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined in the description. The compounds of formula (I) are inhibitors of the YAP/TAZ-TEAD interaction.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 18, 2018
    Inventors: Martine BARTH, Sylvie CONTAL, Christian MONTALBETTI, Luc SPITZER
  • NUCLEAR RECEPTOR MODULATORS
    Publication number: 20160362370
    Abstract: The invention provides compounds of Formula (I) pharmaceutically acceptable salts, thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological conditions.
    Type: Application
    Filed: June 8, 2016
    Publication date: December 15, 2016
    Applicant: AbbVie Inc.
    Inventors: Maria A. Argiriadi, Eric C. Breinlinger, Kevin P. Cusack, Adrian D. Hobson, Dominique Potin, Martine Barth, Jerome Amaudrut, Olivia Poupardin, Laurent Mounier, Michael E. Kort
  • Substituted 2,10-dihydro-9-oxa-1,2,4A-triazaphenanthren-3-ones and uses thereof
    Patent number: 9115151
    Abstract: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: August 25, 2015
    Assignee: AbbVie Inc.
    Inventors: Dawn M. George, Maria A. Argiriadi, Martine Barth, Dominique Bonafoux, Eric C. Breinlinger, Linlin Dai, Jeremy Edmunds, Michael M. Friedman, Fabrice Guillier, Adrian D. Hobson, Dominique Potin, Didier Thomas, Jianfei Wang, Wentao Wu, Yang Zhang
  • TRIAZINONE COMPOUNDS
    Publication number: 20140206663
    Abstract: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
    Type: Application
    Filed: March 19, 2014
    Publication date: July 24, 2014
    Inventors: Jianfei Wang, Eric C. Breinlinger, Martine Barth, Michael M. Friedman, Fabrice Guillier, Maria A. Argiriadi, Jeremy Edmunds, Dominique Potin, Adrian D. Hobson, Wentao Wu, Dominique Bonafoux, Didier Thomas, Dawn M. George, Linlin Dai, Yang Zhang
  • Method of treating conditions involving PPAR-receptors with indole compounds
    Patent number: 8436040
    Abstract: Indole compounds corresponding to the formula (I): as defined in the claims, pharmaceutically acceptable addition salts of such compounds, pharmaceutical compositions containing such compounds, the process for their preparation, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular disease, inflammatory disease and neurodegeneration.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: May 7, 2013
    Assignee: Laboratoires Fournier S.A.
    Inventors: Jean Binet, Benaiessa Boubia, Pierre Dodey, Christiane Legendre, Martine Barth, Olivia Poupardin-Olivier
  • Method of Treating Conditions Involving PPAR-Receptors with Indole Compounds
    Publication number: 20100286137
    Abstract: Indole compounds corresponding to the formula (I): as defined in the claims, pharmaceutically acceptable addition salts of such compounds, pharmaceutical compositions containing such compounds, the process for their preparation, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular disease, inflammatory disease and neurodegeneration.
    Type: Application
    Filed: June 7, 2010
    Publication date: November 11, 2010
    Applicant: Laboratories Fournier S.A.
    Inventors: Jean BINET, Benaïssa Boubia, Pierre Dodey, Christiane Legendre, Martine Barth, Olivia Poupardin-Olivier
  • Indole compounds, method of preparing them and uses thereof
    Patent number: 7795297
    Abstract: Indole compounds corresponding to the formula (I): as defined in the claims, pharmaceutically acceptable addition salts of such compounds, pharmaceutical compositions containing such compounds, the process for their preparation, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular disease, inflammatory disease and neurodegeneration.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: September 14, 2010
    Assignee: Laboratories Fournier S.A.
    Inventors: Jean Binet, Benaiessa Boubia, Pierre Dodey, Christiane Legendre, Martine Barth, Olivia Poupardin-Olivier
  • Use of pyrrolopyridine compounds for activating PPAR receptors and treatment of conditions involving such receptors
    Patent number: 7728002
    Abstract: A method of activating PPAR receptors in a subject, said method comprising administering to said subject an effective PPAR receptor activating amount of a pyrrolopyridine compound corresponding to formula (I): wherein R, R1, R2, R3, R4, X, Ar and n have defined meanings, or a pharmaceutically acceptable salt thereof, particularly as part of the treatment of a disorder or disease state selected from the group consisting of atherosclerosis, myocardial infarction, hypertension, and cerebral vascular disease.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: June 1, 2010
    Assignee: Laboratoires Fournier S.A.
    Inventors: Benaïssa Boubia, Martine Barth, Jean Binet, Pierre Dodey, Christiane Legendre, Olivia Poupardin-Olivier
  • Use of Pyrrolopyridine Compounds for Activating PPAR Receptors and Treatment of Conditions Involving Such Receptors
    Publication number: 20090239856
    Abstract: A method of activating PPAR receptors in a subject, said method comprising administering to said subject an effective PPAR receptor activating amount of a pyrrolopyridine compound corresponding to formula (I): wherein R, R1, R2, R3, R4, X, Ar and n have defined meanings, or a pharmaceutically acceptable salt thereof, particularly as part of the treatment of a disorder or disease state selected from the group consisting of atherosclerosis, myocardial infarction, hypertension, and cerebral vascular disease.
    Type: Application
    Filed: June 2, 2009
    Publication date: September 24, 2009
    Applicant: LABORATOIRES FOURNIER S.A.
    Inventors: Benaissa Boubia, Martine Barth, Jean Binet, Pierre Dodey, Christiane Legendre, Olivia Poupardin-Olivier
  • Pyrrolopyridine compounds, method of making them and uses thereof
    Patent number: 7557122
    Abstract: Pyrrolopyridine compounds corresponding to formula (I): as defined in the claims, pharmaceutically acceptable salts thereof, the process for preparing such compounds, pharmaceutical compositions containing such compounds, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular diseases, inflammatory diseases and neurodegenerative diseases.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: July 7, 2009
    Assignee: Laboratoires Fournier S.A.
    Inventors: Benaïssa Boubia, Martine Barth, Jean Binet, Pierre Dodey, Christiane Legendre, Olivia Poupardin-Olivier
  • Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain
    Patent number: 7538111
    Abstract: The present invention concerns novel benzenesulphonamide compounds, defined by formula I. Therapeutic compositions comprising the benzenesulphonamide compounds of the invention or salts thereof and methods for producing the benzenesulphonamide compounds of the invention are also disclosed. The benzenesulphonamide compounds of the invention or salts thereof are useful for treating pain, such as hyperalgesia and major algesia.
    Type: Grant
    Filed: March 24, 2004
    Date of Patent: May 26, 2009
    Assignee: Laboratoires Fournier S.A.
    Inventors: Martine Barth, Michel Bondoux, Pierre Dodey, Christine Massardier, Didier Thomas, Jean-Michel Luccarini
  • Pyrrolopyridine Compounds, Method of Making Them and Uses Thereof
    Publication number: 20080200495
    Abstract: Pyrrolopyridine compounds corresponding to formula (I): as defined in the claims, pharmaceutically acceptable salts thereof, the process for preparing such compounds, pharmaceutical compositions containing such compounds, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular diseases, inflammatory diseases and neurodegenerative diseases.
    Type: Application
    Filed: February 29, 2008
    Publication date: August 21, 2008
    Applicant: LABORATOIRES FOURNIER S.A.
    Inventors: Benaissa Boubia, Martine Barth, Jean Binet, Pierre Dodey, Christiane Legendre, Olivia Poupardin-Olivier
  • Indole Compounds, Method of Preparing Them and Uses Thereof
    Publication number: 20080153816
    Abstract: Indole compounds corresponding to the formula (I): as defined in the claims, pharmaceutically acceptable addition salts of such compounds, pharmaceutical compositions containing such compounds, the process for their preparation, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular disease, inflammatory disease and neurodegeneration.
    Type: Application
    Filed: February 28, 2008
    Publication date: June 26, 2008
    Applicant: Laboratoires Fournier S.A.
    Inventors: Jean BINET, Benaissa Boubia, Pierre Dodey, Christiane Legendre, Martine Barth, Olivia Poupardin-Olivier