Abstract: System for endocardial injection are disclosed. An example system may include a first steerable catheter having a first lumen formed therein. A second steerable catheter may be disposed within the first lumen. The second steerable catheter may have a second lumen formed therein. An injection catheter may be disposed within the second lumen. The injection catheter may have a distal end region. The distal end region may include an imaging section and a needle section. The system may include an imaging device configured to be disposed within the imaging section.

Abstract: An esophageal stent configured to span a stricture may include a tubular body configured to shift between a delivery configuration and a deployed configuration, the tubular body having a first end and a second end. In the deployed configuration: the tubular body defines a first flange portion, a second flange portion, and a saddle portion extending from the first flange portion to the second flange portion; the tubular body further defining an overall longitudinal length extending from the first end to the second end; the first flange portion has a first outer radial extent, and the second flange portion has a second outer radial extent; the first outer radial extent and the second outer radial extent are greater than an outer radial extent of the saddle portion; and a longitudinal length of the saddle portion is at least 50% of the overall longitudinal length of the tubular body.

Abstract: Medical devices and related methods useful for EVAC procedures are described. The medical device may include a sponge. The sponge may include a plurality of perforations that form one or more tear surfaces. The one or more tear surfaces may define a predefined location for removing a first portion of the sponge from a second portion of the sponge. The one or more tear surfaces may form a boundary between a radially inner surface of the first portion and a radially outer surface of the second portion. The medical device may further include a tube coupled to a proximal portion of the sponge.

Abstract: A medical stent includes an elongate tubular body extending from a proximal end region to a distal end region. The distal end region of the elongate tubular body may be adapted to resist migration as a result of peristaltic force. The distal end region of the elongate tubular body may include two or more longitudinally-extending voids and two or more longitudinally-extending dynamic engagement features that are defined between adjacent longitudinally-extending voids. The two or more longitudinally-extending dynamic engagement features are adapted to splay radially outwardly in response to an applied peristaltic force, thereby dissipating the applied peristaltic force.

Abstract: The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.

Abstract: An example medical device is disclosed as an expandable stent. The stent includes a tubular scaffold having an inner surface, an outer surface, and a lumen extending therein. The expandable stent also includes a liner disposed within the lumen of the tubular scaffold. Further, the liner is radially spaced from a medial region of the tubular scaffold to define a tissue ingrowth region along an uncovered portion of the medial region. Additionally, the liner extending along the tissue ingrowth region is configured to limit the amount of tissue ingrowth along the medial region of the scaffold.

Abstract: A polymeric stent includes a polymeric tubular body extending from a distal region to a proximal region, the polymeric tubular body adapted to have a negative Poisson's ratio. A distal engagement feature is formed within the distal region and a proximal engagement feature is formed within the proximal region. A delivery device for the polymeric stent includes a tubular body having an outer surface adapted to accommodate the polymeric stent thereover. A distal stent engagement member is secured relative to the tubular body and is adapted to releasably engage the distal engagement feature. A proximal stent engagement member is secured relative to the tubular body and is adapted to releasably engage the proximal engagement feature. The tubular body is adapted to affect a change in a distance between the distal stent engagement member and the proximal stent engagement member, thereby changing a length of the polymeric stent.

Abstract: An implantable treatment device configured to facilitate removal thereof after tissue ingrowth into a portion thereof, such as into an enlarged region with a diameter greater than adjacent regions. A liner is positioned within a lumen of the treatment device, with a portion spaced from the enlarged region of the treatment device. A disruption zone in the liner facilitates controlled disruption of the liner's integrity to permit a portion of a removal device inserted within the liner to extend through the liner to interact with the treatment device. The treatment device may be part of a treatment system including a removal device with an enlarged region corresponding to the treatment device enlarged region. A method of treatment involves rupturing a rupture zone in a treatment device liner to allow a portion of a removal device to extend through the liner and into engagement with a portion of the treatment device.

Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member configured to move between a collapsed configuration and an expanded configuration. The elongated tubular member may comprise at least one twisted filament, such as a knitted filament having a plurality of twisted knit stitches with intermediate rung portions extending between adjacent twisted knit stitches, or a plurality of helical filaments twisted with a plurality of longitudinal filaments.

Abstract: A medical stent includes a central stent segment, a proximal stent segment adapted to be positioned over a proximal region of the central stent segment, and a distal stent segment adapted to be positioned over a distal region of the central stent segment. A polymeric coating extends over the proximal stent segment, the distal stent segment and at least a portion of the central stent segment, the polymeric coating adapted to allow the proximal stent segment to float over the proximal region of the central stent segment and to allow the distal stent segment to float over the distal region of the central stent segment. Upon implantation, the central stent segment is adapted to translate relative to the proximal stent segment and the distal stent segment in response to peristaltic forces.

Abstract: An illustrative stent includes an elongated tubular member comprising at least one strut forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating may be disposed on the elongated tubular member and spanning at least some of the plurality of cells. One or more magnetic components may be disposed on or within the coating.

Abstract: Devices, systems, and methods for deploying a biliary stent. A biliary stent has lobes and creases to expand between contracted and expanded positions. The stent is delivered to a bile duct in a contracted position loaded on a shaft of a delivery device. When the shaft is retracted through the stent, wings on the shaft force the stent outward into the larger expanded position. In the expanded position, the creases form drainage channels to reduce blockage over the life of the stent.

Abstract: Example medical stents are disclosed. An example stent includes a tubular framework including an inner surface, an outer surface and a lumen extending therethrough. Additionally, the stent includes a tissue ingrowth scaffold extending along a portion of the outer surface of the tubular framework, wherein the tissue ingrowth scaffold is spaced radially away from the outer surface of the tubular framework to define an expansion cavity therebetween and wherein the tissue ingrowth scaffold permits tissue ingrowth along a portion thereof. Further, the stent includes an expandable member positioned within at least a portion of the expansion cavity.

Abstract: The present disclosure provides medical devices such as self-expanding stents or tissue lumen stents with an overlapping layer. The medical devices can have a coating or cover disposed over all or a portion of the medical device. The overlapping layer define a doubled back portion at an end of the medical device that includes an elongate section to provide dynamic movement of the end of the medical device relative to a central portion of the medical device.

Abstract: A medical device including a distal body coupled to a distal end of a vacuum tube. The distal body may be in fluid communication with a lumen of the vacuum tube. The distal body may include a core having a plurality of openings and one or more layers surrounding the core.

Abstract: According to one aspect, an apparatus for treating tissue may include an elongate tube. The elongate tube may include a slot extending longitudinally along a first side of the elongate tube, a first elongate jaw member on a first side of the slot, and a second elongate jaw member on a second side of the slot. The apparatus may also include a shaft coupled to the elongate tube along a second side of the elongate tube. The first elongate jaw member may be movably coupled to the shaft, such that the first elongate jaw member may be movable toward the second elongate jaw member to converge tissue walls within the slot and cut the tissue walls within the slot.

Abstract: An implantable treatment device configured to facilitate removal thereof after tissue ingrowth into a portion thereof, such as into an enlarged region with a diameter greater than adjacent regions. A liner is positioned within a lumen of the treatment device, with a portion spaced from the enlarged region of the treatment device. A disruption zone in the liner facilitates controlled disruption of the liner's integrity to permit a portion of a removal device inserted within the liner to extend through the liner to interact with the treatment device. The treatment device may be part of a treatment system including a removal device with an enlarged region corresponding to the treatment device enlarged region. A method of treatment involves rupturing a rupture zone in a treatment device liner to allow a portion of a removal device to extend through the liner and into engagement with a portion of the treatment device.

Abstract: An illustrative endoluminal implant having an elongated tubular member. The elongate tubular member having a proximal stent, a distal stent and an interconnecting sleeve. The proximal stent tapers from a first outer diameter adjacent the proximal end region to a second smaller outer diameter adjacent the distal end region. The distal stent has an outer diameter less than the first outer diameter of the proximal stent. The interconnecting sleeve is collapsible in response to an applied radial force such that the sleeve is positionable across a natural valve or sphincter.

Abstract: A stent includes a tubular body formed of one or more interwoven wires, the tubular body having first and second opposing open ends and a lumen extending therebetween. The stent further includes a first anchor member disposed adjacent the first open end and a second anchor member disposed adjacent the second open end, the first and second anchor members each extending radially outward from the tubular body, the first and second anchor members each having an outer diameter larger than an outer diameter of the tubular body disposed between the first and second anchor members. A plurality of spacer members are disposed around the first open end and extending longitudinally beyond the first open end, wherein when a pulling force is applied to the spacer members, the outer diameter of the tubular body is not reduced.

Abstract: Example medical stents are disclosed. An example stent includes a tubular framework including an inner surface, an outer surface and a lumen extending therethrough. Additionally, the stent includes a tissue ingrowth scaffold extending along a portion of the outer surface of the tubular framework, wherein the tissue ingrowth scaffold is spaced radially away from the outer surface of the tubular framework to define an expansion cavity therebetween and wherein the tissue ingrowth scaffold permits tissue ingrowth along a portion thereof. Further, the stent includes an expandable member positioned within at least a portion of the expansion cavity.