Abstract: A system for maintaining patency of a body lumen may include a first endoprosthesis configured to shift from a straightened configuration to a helical configuration defining a plurality of loops, and a second endoprosthesis configured to shift from a radially collapsed configuration toward a radially expanded configuration. The plurality of loops defines a passage having an inner diameter. At least a portion of the second endoprosthesis is disposed within the passage in the radially expanded configuration. A method of maintaining patency of a body lumen may include advancing a first endoprosthesis into a first body lumen in a straightened configuration, deploying the first endoprosthesis within the first body lumen in a helical configuration defining a plurality of loops, advancing a second endoprosthesis into the first body lumen in a radially collapsed configuration, and shifting the second endoprosthesis to a radially expanded configuration within the plurality of loops.

Abstract: A mandrel for forming a stent with a tapered profile and one or more anti-migration features includes a first stent shaping segment having a first diameter, a second stent shaping segment having a second diameter less than the first diameter and a tapered segment disposed therebetween. A third stent shaping segment is releasably securable to the second stent shaping segment and has a third diameter greater than the second diameter. One or more movable pins are outwardly extendable from corresponding apertures formed within the tapered segment. An actuation element is engagable with the first stent shaping segment and includes a tapered surface configured to engage the one or more movable pins and support the one or more movable pins extended from the corresponding apertures.

Abstract: An illustrative endoluminal implant having an elongated tubular member. The elongated tubular member having a stent and a retrieval suture interwoven with the stent. The retrieval suture including a first suture loop extending about a circumference of the stent and adjacent to a suture retrieval loop and a second suture loop extending about a circumference of the stent and longitudinally spaced from the first suture loop. The first and second suture loops coupled via one or more interconnecting segments. At least one of the first or second suture loops has an arc length of less than 270° of the circumference of the stent.

Abstract: An endoprosthesis may include an expandable framework configured to shift between a delivery configuration and a deployed configuration, and a covering including a plurality of polymeric cover segments disposed about at least a portion of the expandable framework. A portion of each of the plurality of polymeric cover segments may be fixedly attached to the expandable framework. The plurality of polymeric cover segments is longitudinally spaced apart from each other in the delivery configuration. The plurality of polymeric cover segments longitudinally overlaps each other in the deployed configuration.

Abstract: The disclosure provides a tissue lumen stent that has an elongated tubular configuration and a foreshortened configuration in which the upstream, the downstream, or both the upstream and downstream ends expand radially into flanged and/or flared structures while the region therebetween is generally cylindrical. The upstream flange structure has a larger maximum lateral dimension, axial width and/or axial radius than that of the downstream flange structure and may include an inclined portion having an axial length at least as long as a maximum diameter of the saddle region when the body is in the foreshortened configuration.

Abstract: A knitted stent extending along a central longitudinal axis may comprise a filament forming a plurality of cells arranged in a plurality of columns and a plurality of rows. The plurality of rows may extend parallel to the central longitudinal axis. The plurality of columns may extend circumferentially around the central longitudinal axis. The plurality of rows may include a plurality of loop rows and a plurality of rung rows interposed between adjacent loop rows. Each cell within the plurality of loop rows may include a circumferential loop element connected to two longitudinally oriented connector elements. The plurality of rung rows may include a plurality of circumferential rung elements connected to adjacent loop rows. A majority of the plurality of loop rows may include open cells having an open end. At least one of the plurality of loop rows may include a plurality of closed cells having a closed end.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to delivery systems configured to position a distal portion of a medical device within a restricted anatomical area. In one example, a delivery system may include a flexible elongate member with an inner member within a lumen of the flexible elongate member. A stent may be constrained therebetween. The stent may be configured to move between a first configuration to a second deployed configuration when unconstrained from the flexible elongate member. When the stent moves from the first configuration to the second configuration, the inner member may change from a first length to a second, shorter length. Other embodiments are contemplated.

Abstract: An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including first and second regions, each of the first and second regions include a plurality of interstices located therein. The medical device also includes a covering spanning each of the plurality of interstices of the first region. The second region is free of the covering. A biodegradable gripping material is disposed on an outer surface of the covering. Further, the expandable scaffold is configured to shift from a collapsed state to an expanded state and the second region is configured to contact an inner surface of the body lumen in the expanded state. Additionally, the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen.

Abstract: A mandrel for forming a stent with a tapered profile and one or more anti-migration features includes a first stent shaping segment having a first diameter, a second stent shaping segment having a second diameter less than the first diameter and a tapered segment disposed therebetween. A third stent shaping segment is releasably securable to the second stent shaping segment and has a third diameter greater than the second diameter. One or more movable pins are outwardly extendable from corresponding apertures formed within the tapered segment. An actuation element is engagable with the first stent shaping segment and includes a tapered surface configured to engage the one or more movable pins and support the one or more movable pins extended from the corresponding apertures.

Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member configured to move between a collapsed configuration and an expanded configuration. The elongated tubular member may comprise at least one twisted filament, such as a knitted filament having a plurality of twisted knit stitches with intermediate rung portions extending between adjacent twisted knit stitches, or a plurality of helical filaments twisted with a plurality of longitudinal filaments.

Abstract: An illustrative endoluminal implant having an elongated tubular member. The elongated tubular member having a stent and a retrieval suture interwoven with the stent. The retrieval suture including a first suture loop extending about a circumference of the stent and adjacent to a suture retrieval loop and a second suture loop extending about a circumference of the stent and longitudinally spaced from the first suture loop. The first and second suture loops coupled via one or more interconnecting segments. At least one of the first or second suture loops has an arc length of less than 270° of the circumference of the stent.

Abstract: A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.

Abstract: A medical device, comprising a tube having a sidewall defining a lumen within the tube, wherein a plurality of openings extend through a distal portion of the sidewall and are in fluid communication with the lumen; a support structure coupled to the distal portion of the sidewall, the support structure having a contracted configuration and an expanded configuration, and the support structure having support openings through a wall of the support structure; and a porous body over at least a portion of the support structure.

Abstract: A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.

Abstract: The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.

Abstract: A medical stent having a first end, a second end, and a central longitudinal axis extending from the first end to the second end, may include a plurality of first filaments each extending in a first helical path around the central longitudinal axis in a first direction and a plurality of second filaments each extending in a second helical path around the central longitudinal axis in a second direction. The plurality of first filaments may be interwoven with the plurality of second filaments. The first helical path of at least one of the plurality of first filaments may include a circumferential offset disposed between the first end and the second end.

Abstract: A stent including a tubular body formed of one or more interwoven wires, a first anchor member disposed adjacent the first open end of the stent, a second anchor member disposed adjacent the second open end of the stent, and at least one divider disposed between the first and second anchor members. The first and second anchor members and the divider extend radially outward from the tubular body to divide the tubular body into at least a first saddle region extending between the first anchor member and the divider and a second saddle region extending between the second anchor member and the divider.

Abstract: The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.

Abstract: The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Abstract: An illustrative endoluminal implant having an elongated tubular member. The elongate tubular member having a proximal stent, a distal stent and an interconnecting sleeve. The proximal stent tapers from a first outer diameter adjacent the proximal end region to a second smaller outer diameter adjacent the distal end region. The distal stent has an outer diameter less than the first outer diameter of the proximal stent. The interconnecting sleeve is collapsible in response to an applied radial force such that the sleeve is positionable across a natural valve or sphincter.