Patents by Inventor Marvin M. Hoehn
Marvin M. Hoehn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5239064Abstract: A novel antibiotic complex, A59770, individual factors and derivatives thereof, are provided. The A59770 compounds are useful as pesticides, particularly as rodenticides. Further provided are methods for reducing a rodent population, rodenticidal compositions, and an A59770-producing Amycolatopsis orientalis culture.Type: GrantFiled: April 11, 1990Date of Patent: August 24, 1993Assignee: Eli Lilly and CompanyInventors: Marvin M. Hoehn, Karl H. Michel, Raymond C. Yao
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Patent number: 4994270Abstract: New peptide antibiotic A54145, individual A54145 components A, A.sub.1, B, B.sub.1, C, D, E and F and their pharmaceutically acceptable salts, are useful antibacterial agents which also improve growth performance in animals, especially poultry. Biologically pure cultures of the A54145-producing Streptomyces fradiae cultures NRRL 18158, NRRL 18159 and NRRL 18160 cultures and methods of making antibiotic A54145 using those cultures are also provided.Type: GrantFiled: April 11, 1988Date of Patent: February 19, 1991Assignee: Eli Lilly and CompanyInventors: LaVerne D. Boeck, David S. Fukuda, Jon S. Mynderse, Marvin M. Hoehn, Ralph E. Kastner, Harold R. Papiska
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Patent number: 4717714Abstract: The novel glycopeptide antibiotic A-51568B is produced by submerged, aerobic fermentation of Nocardia orientalis NRRL 15232. A-51568B demonstrates antibiotic activity against gram-positive bacteria.Type: GrantFiled: September 12, 1986Date of Patent: January 5, 1988Assignee: Eli Lilly and CompanyInventors: LaVerne D. Boeck, Gary G. Marconi, Marvin M. Hoehn
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Patent number: 4558009Abstract: Antibiotic A-51568 is produced by submerged, aerobic fermentation of new Nocardia orientalis NRRL 15232. The antibiotic is effective against gram-positive organisms.Type: GrantFiled: December 27, 1983Date of Patent: December 10, 1985Assignee: Eli Lilly and CompanyInventors: LaVerne D. Boeck, Marvin M. Hoehn, Gary G. Marconi
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Patent number: 4558008Abstract: The novel glycopeptide antibiotic A-51568B is produced by submerged, aerobic fermentation of Nocardia orientalis NRRL 15232. A-51568B demonstrates antibiotic activity against gram-positive bacteria.Type: GrantFiled: December 13, 1983Date of Patent: December 10, 1985Assignee: Eli Lilly and CompanyInventors: LaVerne D. Boeck, Gary G. Marconi, Marvin M. Hoehn
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Patent number: 4495179Abstract: Antibiotic A51568 is produced by submerged, aerobic fermentation of new Nocardia orientalis NRRL 15232. The antibiotic is gram-positive.Type: GrantFiled: December 16, 1983Date of Patent: January 22, 1985Assignee: Eli Lilly and CompanyInventors: Marvin M. Hoehn, Gary G. Marconi
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Patent number: 4431809Abstract: Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic and the diacetyl and triacetyl derivatives thereof disclosed herein have shown antibacterial activity against Staphylococcus and Streptococcus species which are penicillin resistant. In addition, the antibiotic and its tetraacetyl derivative have shown antiviral and antitrichomonal activity in vitro.Type: GrantFiled: May 7, 1982Date of Patent: February 14, 1984Assignee: Eli Lilly and CompanyInventors: Marvin M. Hoehn, Karl H. Michel
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Patent number: 4400510Abstract: Antibiotic A-32256 which is produced by submerged, aerobic fermentation of a Streptomyces sp. NRRL 12067. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus and various anaerobic species. In addition, the antibiotic has shown antitrichomonas activity in vitro, as well as activity for improving ruminant feed efficency and as a mosquito larvacide.Type: GrantFiled: September 21, 1981Date of Patent: August 23, 1983Assignee: Eli Lilly and CompanyInventors: Karl H. Michel, Marvin M. Hoehn
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Patent number: 4375462Abstract: Antibiotic A-32724 complex, comprising microbiologically-active, related factors A, B and C, is produced by submerged, aerobic fermentation of a strain of Chaetomella raphigera Swift NRRL 12331. The A-32724 antibiotics are closely related antibiotics. The individual A-32724 factors are separated by chromatography. In addition to their antibacterial activity, the A-32724 factors inhibit certain enzymes and exhibit antihypertensive properties.Type: GrantFiled: September 16, 1981Date of Patent: March 1, 1983Assignee: Eli Lilly and CompanyInventors: David H. Berg, Marvin M. Hoehn
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Patent number: 4358584Abstract: Antibiotic compounds of the formula: ##STR1## wherein R' is ##STR2## or --CH.sub.2 OH, and the non-toxic pharmaceutically acceptable acid addition salts thereof, are produced by culturing Streptomyces flocculus NRRL 11459. Techniques for isolating the compounds are also described. Cirramycin A.sub.1 and cirramycin B are coproduced.Type: GrantFiled: September 22, 1980Date of Patent: November 9, 1982Assignee: Eli Lilly and CompanyInventors: Stephen M. Nash, Kay F. Koch, Marvin M. Hoehn
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Patent number: 4336333Abstract: Tunicamycin is produced by the cultivation of Streptomyces chartreusis Calhoun and Johnson, 1956, NRRL 12338. Methods of recovering tunicamycin and for separating and isolating individual factors A.sub.1, A.sub.2, B.sub.1, B.sub.2, C.sub.1, C.sub.2, D.sub.1 and D.sub.2 from tunicamycin complex are described.Type: GrantFiled: March 13, 1981Date of Patent: June 22, 1982Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn, LaVerne D. Boeck
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Patent number: 4331594Abstract: Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors, C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes, the A-21978C factors, and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.Type: GrantFiled: November 14, 1980Date of Patent: May 25, 1982Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn
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Patent number: 4331658Abstract: Method and compositions for treatment of swine dysentery with antibiotic A-32887 (K-41). Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109.Type: GrantFiled: February 22, 1980Date of Patent: May 25, 1982Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn
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Patent number: 4329472Abstract: Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus species which are penicillin resistant. In addition, the antibiotic has shown antirival and antitrichomonal activity in vitro.Type: GrantFiled: April 13, 1981Date of Patent: May 11, 1982Assignee: Eli Lilly and CompanyInventors: Marvin M. Hoehn, Karl H. Michel
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Patent number: 4316959Abstract: Antibiotic A-32256 which is produced by submerged, aerobic fermentation of a Streptomyces sp. NRRL 12067. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus and various anaerobic species. In addition, the antibiotic has shown antitrichomonas activity in vitro, as well as activity for improving ruminant feed efficency and as a mosquito larvacide.Type: GrantFiled: April 28, 1980Date of Patent: February 23, 1982Assignee: Eli Lilly and CompanyInventors: Karl H. Michel, Marvin M. Hoehn
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Patent number: 4303647Abstract: Methods and compositions for treatment of coccidiosis in poultry with antibiotic A-32887 (K-41). Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109.Type: GrantFiled: February 22, 1980Date of Patent: December 1, 1981Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn
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Patent number: 4293649Abstract: Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus species which are penicillin resistant. In addition, the antibiotic has shown antiviral and antitrichomonal activity in vitro.Type: GrantFiled: February 21, 1980Date of Patent: October 6, 1981Assignee: Eli Lilly and CompanyInventors: Marvin M. Hoehn, Karl H. Michel
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Patent number: RE31396Abstract: Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes; the A-21978C factors; and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.Type: GrantFiled: July 19, 1982Date of Patent: September 27, 1983Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn
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Patent number: RE32333Abstract: Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes; the A-21978C factors; and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.Type: GrantFiled: September 26, 1985Date of Patent: January 20, 1987Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn
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Patent number: RE32455Abstract: Antibiotic A-21978C complexes, in particular the A-21978C complex, comprising microbiologically active, related factors, C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-21978C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes, the A-21978C factors, and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.Type: GrantFiled: September 26, 1985Date of Patent: July 7, 1987Assignee: Eli Lilly and CompanyInventors: Robert L. Hamill, Marvin M. Hoehn