Patents by Inventor Marvin M. Hoehn

Marvin M. Hoehn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotics A6888C and A6888X
    Patent number: 4252898
    Abstract: Antibiotic compounds of the formula: ##STR1## wherein R' is ##STR2## or --CH.sub.2 OH, and the non-toxic pharmaceutically acceptable acid addition salts thereof, are produced by culturing Streptomyces flocculus NRRL 11459. Techniques for isolating the compounds are also described. Cirramycin A.sub.1 and cirramycin B are coproduced.
    Type: Grant
    Filed: May 23, 1979
    Date of Patent: February 24, 1981
    Assignee: Eli Lilly and Company
    Inventors: Stephen M. Nash, Kay F. Koch, Marvin M. Hoehn
  • A-21978 Antibiotics and process for their production
    Patent number: 4208403
    Abstract: Antibiotic A-21978 complexes, in particular the A-21978C complex, comprising microbiologically active, related factors C.sub.0, C.sub.1, C.sub.2, C.sub.3, C.sub.4, and C.sub.5. A-21978 complex and A-21978C complex are produced by submerged aerobic fermentation of Streptomyces roseosporus NRRL 11379. The individual A-29178C factors are separated and isolated by chromatography. The A-21978 and A-21978C complexes; the A-21978C factors; and pharmaceutically acceptable salts thereof are antibacterial agents and improve growth promotion in poultry.
    Type: Grant
    Filed: October 16, 1978
    Date of Patent: June 17, 1980
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, Marvin M. Hoehn
  • Antibiotic A-32887 and process for production thereof
    Patent number: 4133876
    Abstract: Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109. A-32887 is an antibacterial, antiprotozoal, anticoccidial, and insecticidal agent. A-32887 also increases feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: May 31, 1977
    Date of Patent: January 9, 1979
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, Marvin M. Hoehn
  • Antibiotic A-32887
    Patent number: 4132778
    Abstract: Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109. A-32887 is an antibacterial, antiprotozoal, anticoccidial, and insecticidal agent. A-32887 also increases feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: October 3, 1977
    Date of Patent: January 2, 1979
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, Marvin M. Hoehn
  • Method of increasing feed utilization
    Patent number: 4085224
    Abstract: Antibiotic A-28086 complex, comprising microbiologically active, structurally related factors A, B, and D, produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 5758. Individual factors A, B, and D are separated and isolated by chromatography. The A-28086 antibiotics are antibacterial, antifungal, antiviral, anti-PPLO, anticoccidial, insecticidal and acaricidal agents and also increase feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: September 2, 1976
    Date of Patent: April 18, 1978
    Assignee: Eli Lilly and Company
    Inventors: David H. Berg, Robert L. Hamill, Marvin M. Hoehn
  • 7-(5-Amino-5-carboxyvaleramido)-7-methoxycephalosporanic acid
    Patent number: 4054564
    Abstract: Antibiotic A16884 and its salts, having antibacterial and anthelmintic activity, prepared by fermentation of Streptomyces lipmanii NRRL 3584.
    Type: Grant
    Filed: May 8, 1972
    Date of Patent: October 18, 1977
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, Calvin E. Higgens, Marvin M. Hoehn
  • Antibiotic A-28086 and process for production thereof
    Patent number: 4038384
    Abstract: Antibiotic A-28086 complex, comprising microbiologically active, structurally related factors A, B, and D, produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 5758. Individual factors A, B, and D are separated and isolated by chromatography. The A-28086 antibiotics are antibacterial, antifungal, antiviral, anti-PPLO, anticoccidial, insecticidal and acaricidal agents and also increase feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: April 21, 1975
    Date of Patent: July 26, 1977
    Assignee: Eli Lilly and Company
    Inventors: David H. Berg, Robert L. Hamill, Marvin M. Hoehn
  • Antibiotic A-28086 and process for production thereof
    Patent number: 4035481
    Abstract: Antibiotic A-28086 complex, comprising microbiologically active, structurally related factors A, B, and D, produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 5758. Individual factors A, B, and D are separated and isolated by chromatography. The A-28086 antibiotics are antibacterial, antifungal, antiviral, anti-PPLO, anticoccidial, insecticidal and acaricidal agents and also increase feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: May 10, 1976
    Date of Patent: July 12, 1977
    Assignee: Eli Lilly and Company
    Inventors: David H. Berg, Robert L. Hamill, Marvin M. Hoehn
  • Antibiotic A-30912 and process for production thereof
    Patent number: 4024245
    Abstract: Antibiotic A-30912 complex, comprising microbiologically active, structurally related factors A, B, C, D, E, F and G, is produced by submerged aerobic fermentation of Aspergillus rugulosus NRRL 8113. The A-30912 factors A, B, C, D, E, F, and G are separated from the A-30912 complex by chromatography. The A-30912 complex and individual factors A, B, C, D, E, F, and G are antifungal agents.
    Type: Grant
    Filed: August 25, 1976
    Date of Patent: May 17, 1977
    Assignee: Eli Lilly and Company
    Inventors: Marvin M. Hoehn, Karl H. Michel
  • Antibiotic A-30641 and process for production thereof
    Patent number: 4001086
    Abstract: Antibiotic A-30641, a new epidithiodiketopiperazine antifungal agent, is produced together with canadensolide in the A-30641 antibiotic complex by submerged aerobic fermentation of Aspergillus tamarii NRRL 8101.
    Type: Grant
    Filed: April 12, 1976
    Date of Patent: January 4, 1977
    Assignee: Eli Lilly and Company
    Inventors: David H. Berg, Robert L. Hamill, Marvin M. Hoehn
  • Antibiotic A-30641
    Patent number: 3991052
    Abstract: Antibiotic A-30641, a new epidithiodiketopiperazine antifungal agent, is produced together with canadensolide in the A-30641 antibiotic complex by submerged aerobic fermentation of Aspergillus tamarii NRRL 8101.
    Type: Grant
    Filed: July 18, 1975
    Date of Patent: November 9, 1976
    Assignee: Eli Lilly and Company
    Inventors: David H. Berg, Robert L. Hamill, Marvin M. Hoehn
  • Antibiotic A-32390 and process for preparation thereof
    Patent number: 3986928
    Abstract: Antibiotic A-32390 complex, comprising factor A and other structurally related factors, is produced by cultivation of Pyrenochaeta sp. NRRL 5786 under submerged aerobic conditions, and isolated by extraction of the broth. Individual A-32390 factor A is separated by chromatography. The A-32390 complex, individual factor A and acyl ester derivatives of factor A inhibit dopamine-.beta.-hydroxylase and have antifungal, antibacterial, and hypotensive activity.
    Type: Grant
    Filed: February 19, 1976
    Date of Patent: October 19, 1976
    Assignee: Eli Lilly and Company
    Inventors: Gary G. Marconi, Marvin M. Hoehn
  • 1,6-Di-O-(2-isocyano-3-methylcrotonyl)-D-mannitol compounds
    Patent number: 3979433
    Abstract: Antibiotic A-32390 complex, comprising factor A and other structurally related factors, is produced by cultivation of Pyrenochaeta sp. NRRL 5786 under submerged aerobic conditions, and isolated by extraction of the broth. Individual A-32390 factor A is separated by chromatography. The A-32390 complex, individual factor A and acyl ester derivatives of factor A inhibit dopamine-.beta.-hydroxylase and have antifungal, antibacterial, and hypotensive activity.
    Type: Grant
    Filed: July 18, 1972
    Date of Patent: September 7, 1976
    Assignee: Eli Lilly and Company
    Inventors: Gary G. Marconi, Marvin M. Hoehn
  • Antibiotic A16884
    Patent number: 3973015
    Abstract: Antibiotic A16884 and its salts, having antibacterial and anthelmintic activity, prepared by fermentation of Streptomyces lipmanii NRRL 3584.
    Type: Grant
    Filed: May 8, 1972
    Date of Patent: August 3, 1976
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, Calvin E. Higgens, Marvin M. Hoehn
  • Antibiotic A23187 and process for preparation thereof
    Patent number: 3960667
    Abstract: Antibiotic A23187 and process for production thereof by submerged aerobic culture of Streptomyces chartreusis NRRL 3882. The antibiotic demonstrates antimicrobial activity and exhibits ionophorous properties, with a specificity for divalent cations.
    Type: Grant
    Filed: July 8, 1975
    Date of Patent: June 1, 1976
    Assignee: Eli Lilly and Company
    Inventors: Richard M. Gale, Calvin E. Higgens, Marvin M. Hoehn
  • Antibiotic A-26771 factor
    Patent number: 3954972
    Abstract: Antibiotic mixture A-26771, comprising microbiologically active factors A, B and C, produced by fermentation of Penicillium turbatum Westling NRRL 5630, and isolation and separation of the individual factors thereof by extraction, chromatography and crystallization. The A-26771 mixture and factors A, B and C thereof have antifungal and broadspectrum antibacterial activity; factors A and C also have antiviral activity.
    Type: Grant
    Filed: January 17, 1975
    Date of Patent: May 4, 1976
    Assignee: Eli Lilly and Company
    Inventors: Karl H. Michel, Marvin M. Hoehn
  • Antibiotic A-26771 factors and process for production thereof
    Patent number: 3932219
    Abstract: Antibiotic mixture A-26771, comprising microbiologically active factors A, B and C, produced by fermentation of Penicillium turbatum Westling NRRL 5630, and isolation and separation of the individual factors thereof by extraction, chromatography and crystallization. The A-26771 mixture and factors A, B and C thereof have antifungal and broad-spectrum antibacterial activity; factors A and C also have antiviral activity.
    Type: Grant
    Filed: January 17, 1975
    Date of Patent: January 13, 1976
    Assignee: Eli Lilly and Company
    Inventors: Karl H. Michel, Marvin M. Hoehn